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JACC:严格控制血压可减少心血管事件的发生(SPRINT 标准 VS 2014高血压指南)

2016-07-09 phylis 译 MedSci原创

背景:根据第八届国家联合委员会2014高血压(HTN)推荐指南血压控制目标,与APRINT(收缩期血压干预试验)的血压(BP)控制目标不同。目标: 本研究的目的评估高血压成年人达到SPRINT血压控制目标,及2014推荐指南控制目标的比例,及对心血管疾病的发病率和死亡率的影响。方法: 研究者使用2008至2013年韩国国家健康和营养检查调查(N = 13346),以及2007年韩国国民健康保险服务

背景:根据第八届国家联合委员会2014高血压(HTN)推荐指南血压控制目标,与APRINT(收缩期血压干预试验)的血压(BP)控制目标不同。

目标: 本研究的目的评估高血压成年人达到SPRINT血压控制目标,及2014推荐指南控制目标的比例,及对心血管疾病的发病率和死亡率的影响。

方法: 研究者使用2008至2013年韩国国家健康和营养检查调查(N = 13346),以及2007年韩国国民健康保险服务队列的(n = 67965)的数据,评估满足每个标准的比例,受试者符合血压目标的每一个标准。根据2007年韩国国家健康保险服务队列的数据(N = 67965),比较不同血压控制目标,主要心血管事件(非致死性心肌梗死的风险,非致死性卒中或心血管死亡的复合)发生的风险。

结果: 与满足2014年高血压指南的标准相比,满足SPRINT标准的高血压受试者的比例较低(11.9% vs 70.8%)。强化降压组(低SPRINT血压控制目标)10年预测的心血管风险最低,中等程度降压组(高于SPRINT血压控制值,但低于2014年指南推荐目标值)受试者风险居中,而未控制组(高于2014年指南推荐目标值),心血管风险最高(分别为6.15%,7.65%,和9.39%)。多变量校正后,中等程度和未控制组比强化降压组,发生主要心血管事件(HR分别为1.17和1.62)的风险更高。

结论:满足APRINT血压控制目标值的高血压人群低于满足2014年指南血压控制值。严格控制血压与主要心血管事件风险降低相关。

原始出处:

Ko MJ, Jo AJ, et al. Level of Blood Pressure Control and Cardiovascular Events: SPRIN.J Am Coll Cardiol. 2016 Jun 21;67(24):2821-31. 


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    2017-03-03 hbwxf
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    2016-12-18 kalseyzl
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    2016-10-12 1e0ece0dm09(暂无匿称)

    谢谢分享学习

    0

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    2016-10-11 ylzr123

    学习了,好文值得点赞!

    0

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    2016-07-14 owlhealth

    这个挺不错的

    0

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  9. [GetPortalCommentsPageByObjectIdResponse(id=1853547, encodeId=72d3185354e54, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Mar 03 00:03:00 CST 2017, time=2017-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643416, encodeId=52951643416be, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Sat Jul 16 11:03:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1927532, encodeId=7887192e532d5, content=<a href='/topic/show?id=5194166480e' target=_blank style='color:#2F92EE;'>#SPRINT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16648, encryptionId=5194166480e, topicName=SPRINT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c77e138, createdName=kalseyzl, createdTime=Sun Dec 18 03:03:00 CST 2016, time=2016-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988323, encodeId=7b1b1988323b0, content=<a href='/topic/show?id=5a5c56e3945' target=_blank style='color:#2F92EE;'>#控制血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56739, encryptionId=5a5c56e3945, topicName=控制血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Wed Mar 22 07:03:00 CST 2017, time=2017-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146963, encodeId=47ad146963f9, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Wed Oct 12 16:13:02 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145854, encodeId=d409145854bc, content=学习了,好文值得点赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Oct 11 22:16:26 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93107, encodeId=545f9310e6c, content=这个挺不错的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Jul 14 18:36:00 CST 2016, time=2016-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325263, encodeId=21ea1325263e5, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Mon Jul 11 02:03:00 CST 2016, time=2016-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604118, encodeId=4b2d1604118b9, content=<a href='/topic/show?id=c2651026824e' target=_blank style='color:#2F92EE;'>#高血压指南#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102682, encryptionId=c2651026824e, topicName=高血压指南)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Mon Jul 11 02:03:00 CST 2016, time=2016-07-11, status=1, ipAttribution=)]

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