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JNCI：豆浆并非人人都能喝

2014-09-11 佚名 生物探索

豆浆雌激素乳腺癌
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大豆已经成为很多国家的主要主粮，但大豆中富含植物雌激素，人在食用这些豆制类食物后，这些激素就会在体内模拟雌激素，过多食用可能会导致体内激素紊乱，而如果患有相关疾病如乳腺癌，则可能会进一步加重乳腺癌患病情况。尽管一些研究显示亚洲人的摄取大豆的比例在增加，乳腺癌的发生率却在下降，然而这并不能证实大豆对这些病患很友善。日前，一项对已经发生乳腺癌的女性进行研究发现，食用大豆能加重乳腺癌患者的患病情况。相关

大豆已经成为很多国家的主要主粮，但大豆中富含植物雌激素，人在食用这些豆制类食物后，这些激素就会在体内模拟雌激素，过多食用可能会导致体内激素紊乱，而如果患有相关疾病如乳腺癌，则可能会进一步加重乳腺癌患病情况。


尽管一些研究显示亚洲人的摄取大豆的比例在增加，乳腺癌的发生率却在下降，然而这并不能证实大豆对这些病患很友善。

日前，一项对已经发生乳腺癌的女性进行研究发现，食用大豆能加重乳腺癌患者的患病情况。相关研究发表在 Journal of the National Cancer Institute杂志上。

这项研究对140位女性乳腺癌患者进行研究，一组只让她们饮用牛奶，另一组只让她们引用豆浆，研究人员发现，那些饮用豆浆的乳腺癌患者其体内的乳腺癌过度表达，这表明这些患者体内的乳腺癌基因在雌激素的刺激下，非常活跃。而饮用牛奶的患者并没有疾病加重的情况出现。

这可能是乳腺癌与雌激素表面的受体进行结合，从而导致疾病恶化。所以通常来说，女性在患有乳腺癌后，医生都会警告她们远离雌激素，而且她们还会经常服用他莫昔芬等药物来调节雌激素。

“在乳腺癌治疗中，雌激素不是什么好东西。”来自华盛顿乔治敦大学癌症中心的克雷格·乔丹说在一次电话采访中说。

当然这项研究只是发现基因表达如何改变肿瘤，并没有深入了解乳腺癌是如何出现的以及为什么在一些女性中并不会出现这种现象的特例情况。

原始出处：

Shike M1, Doane AS2, Russo L2, Cabal R2, Reis-Filo J2, Gerald W2, Cody H2, Khanin R2, Bromberg J2, Norton L2.The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study.J Natl Cancer Inst. 2014 Sep 4;106(9). pii: dju189. doi: 10.1093/jnci/dju189. Print 2014 Sep.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1933676, encodeId=382919336e6d1, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Wed Sep 17 23:48:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11677, encodeId=5725116e70c, content=不知道在更年期和非更年期患者中有没有分组比较？..., beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ae6b39541, createdName=yuhong979, createdTime=Thu Sep 18 10:15:00 CST 2014, time=2014-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1559933, encodeId=70011559933f1, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f83d15047337, createdName=gostraight, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565942, encodeId=31e31565942d5, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11625, encodeId=fa5f11625e8, content=蜂胶制品也促发乳腺癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.100.152.214, createdTime=Sat Sep 13 00:37:00 CST 2014, time=2014-09-13, status=1, ipAttribution=)]
    2014-09-17 lanyan20020086

    #NCI#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1933676, encodeId=382919336e6d1, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Wed Sep 17 23:48:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11677, encodeId=5725116e70c, content=不知道在更年期和非更年期患者中有没有分组比较？..., beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ae6b39541, createdName=yuhong979, createdTime=Thu Sep 18 10:15:00 CST 2014, time=2014-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1559933, encodeId=70011559933f1, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f83d15047337, createdName=gostraight, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565942, encodeId=31e31565942d5, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11625, encodeId=fa5f11625e8, content=蜂胶制品也促发乳腺癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.100.152.214, createdTime=Sat Sep 13 00:37:00 CST 2014, time=2014-09-13, status=1, ipAttribution=)]
    2014-09-18 yuhong979

    不知道在更年期和非更年期患者中有没有分组比较？...

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1933676, encodeId=382919336e6d1, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Wed Sep 17 23:48:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11677, encodeId=5725116e70c, content=不知道在更年期和非更年期患者中有没有分组比较？..., beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ae6b39541, createdName=yuhong979, createdTime=Thu Sep 18 10:15:00 CST 2014, time=2014-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1559933, encodeId=70011559933f1, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f83d15047337, createdName=gostraight, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565942, encodeId=31e31565942d5, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11625, encodeId=fa5f11625e8, content=蜂胶制品也促发乳腺癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.100.152.214, createdTime=Sat Sep 13 00:37:00 CST 2014, time=2014-09-13, status=1, ipAttribution=)]
    2014-09-13 gostraight

    #豆浆#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1933676, encodeId=382919336e6d1, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Wed Sep 17 23:48:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11677, encodeId=5725116e70c, content=不知道在更年期和非更年期患者中有没有分组比较？..., beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ae6b39541, createdName=yuhong979, createdTime=Thu Sep 18 10:15:00 CST 2014, time=2014-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1559933, encodeId=70011559933f1, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f83d15047337, createdName=gostraight, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565942, encodeId=31e31565942d5, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11625, encodeId=fa5f11625e8, content=蜂胶制品也促发乳腺癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.100.152.214, createdTime=Sat Sep 13 00:37:00 CST 2014, time=2014-09-13, status=1, ipAttribution=)]
    2014-09-13 智智灵药

    #豆浆#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1933676, encodeId=382919336e6d1, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Wed Sep 17 23:48:00 CST 2014, time=2014-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11677, encodeId=5725116e70c, content=不知道在更年期和非更年期患者中有没有分组比较？..., beContent=null, objectType=article, channel=null, level=null, likeNumber=193, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ae6b39541, createdName=yuhong979, createdTime=Thu Sep 18 10:15:00 CST 2014, time=2014-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1559933, encodeId=70011559933f1, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f83d15047337, createdName=gostraight, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1565942, encodeId=31e31565942d5, content=<a href='/topic/show?id=468192183fb' target=_blank style='color:#2F92EE;'>#豆浆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92183, encryptionId=468192183fb, topicName=豆浆)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Sep 13 06:48:00 CST 2014, time=2014-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=11625, encodeId=fa5f11625e8, content=蜂胶制品也促发乳腺癌, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.100.152.214, createdTime=Sat Sep 13 00:37:00 CST 2014, time=2014-09-13, status=1, ipAttribution=)]
    2014-09-13 114.100.152.214

    蜂胶制品也促发乳腺癌

    0

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