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BMJ:轻中度饮酒量也会增加患癌风险

2015-08-20 MedSci 译 MedSci原创

美国国家酒精滥用与酒精中毒研究所(NIAAA)定义:轻至中度的酒精摄入量为女性1杯/天,男性2杯/天。但根据发表在BMJ杂志的最新研究,即使饮酒达到如此程度仍然会增加民众患癌症的风险。既往的研究内容大多是酗酒会增加民众患某些癌症的风险,包括乳腺癌、结肠癌、肝癌和口腔癌等。但是根据哈佛大学公共卫生学院的Edward Giovannucci博士和他的同事调查发现,轻中度饮酒量也会增加民众的患癌风险。

美国国家酒精滥用与酒精中毒研究所(NIAAA)定义:轻至中度的酒精摄入量为女性1杯/天,男性2杯/天。但根据发表在BMJ杂志的最新研究,即使饮酒达到如此程度仍然会增加民众患癌症的风险。


既往的研究内容大多是酗酒会增加民众患某些癌症的风险,包括乳腺癌结肠癌、肝癌和口腔癌等。

但是根据哈佛大学公共卫生学院的Edward Giovannucci博士和他的同事调查发现,轻中度饮酒量也会增加民众的患癌风险。 且研究者认为,如今单独探究饮酒量(不探究民众的吸烟问题)对民众患癌风险影响的研究少之又少。在饮酒导致癌症的患者中,吸烟往往起协同作用,因为饮酒者往往都会吸烟。因此在探究饮酒量对民众患癌影响的研究中,吸烟是一个混杂因素。

因此Giovannucci博士和他的同事开始探究轻中度饮酒是否会导致民众增加患癌风险,并且钻研对不吸烟的饮酒者而言,饮酒如何危害其自身健康。 

研究人员对美国88084位女性和47881位男士进行了大规模的研究,研究时长达30年之久。参与人员每4年完成一份关于饮酒量的问卷调查,并积极配合随访。

轻中度饮酒的定义为:女性饮酒量为1标准杯/天或15g/天;男性为2标准杯/天或30g/天。一标准杯的定义为饮用葡萄酒118ml或啤酒355ml。同时研究人员定时评估参与者的患癌风险,包括总体的患癌风险和某些肿瘤的患癌风险(包括结肠癌、直肠癌、肝癌、乳腺癌、口腔、咽和食管癌等)。

在30年的随访过程中,被诊断为罹患癌症的女士和男士分别为19269 位和7571 位。研究人员发现,不考虑他们的吸烟史后,轻中度饮酒量的参与者总体的患癌风险并未显著增加,只是轻微影响。但是饮酒量为轻中度的女性患乳腺癌的几率明显增大,而不论其吸烟与否;对轻中度饮酒的男士而言,只有吸烟者才会明显增加其患癌风险。

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    2016-05-21 huangdf
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    2016-04-20 gaoxiaoe
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    2015-09-06 sjq027
  5. [GetPortalCommentsPageByObjectIdResponse(id=1943478, encodeId=9d0819434e8b7, content=<a href='/topic/show?id=0f2122153ec' target=_blank style='color:#2F92EE;'>#中度饮酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22153, encryptionId=0f2122153ec, topicName=中度饮酒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c2b4297, createdName=徐岩, createdTime=Thu Feb 11 16:40:00 CST 2016, time=2016-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952975, encodeId=5b7f19529e5f7, content=<a href='/topic/show?id=6d061012155a' target=_blank style='color:#2F92EE;'>#饮酒量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101215, encryptionId=6d061012155a, topicName=饮酒量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sat May 21 12:40:00 CST 2016, time=2016-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847702, encodeId=5e1a184e702d5, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Apr 20 10:40:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061476, encodeId=3b7520614e6f4, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun Sep 06 09:40:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35968, encodeId=59283596846, content=不错。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sun Aug 23 00:20:00 CST 2015, time=2015-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413431, encodeId=2e6b14134317c, content=<a href='/topic/show?id=3f225299942' target=_blank style='color:#2F92EE;'>#患癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52999, encryptionId=3f225299942, topicName=患癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b2c2959841, createdName=zzc2212, createdTime=Sat Aug 22 10:40:00 CST 2015, time=2015-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601354, encodeId=e83316013540d, content=<a href='/topic/show?id=5baa5299111' target=_blank style='color:#2F92EE;'>#患癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52991, encryptionId=5baa5299111, topicName=患癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat Aug 22 10:40:00 CST 2015, time=2015-08-22, status=1, ipAttribution=)]
    2015-08-23 lecoo

    不错。

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=1943478, encodeId=9d0819434e8b7, content=<a href='/topic/show?id=0f2122153ec' target=_blank style='color:#2F92EE;'>#中度饮酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22153, encryptionId=0f2122153ec, topicName=中度饮酒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c2b4297, createdName=徐岩, createdTime=Thu Feb 11 16:40:00 CST 2016, time=2016-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952975, encodeId=5b7f19529e5f7, content=<a href='/topic/show?id=6d061012155a' target=_blank style='color:#2F92EE;'>#饮酒量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101215, encryptionId=6d061012155a, topicName=饮酒量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Sat May 21 12:40:00 CST 2016, time=2016-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847702, encodeId=5e1a184e702d5, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Apr 20 10:40:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061476, encodeId=3b7520614e6f4, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun Sep 06 09:40:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35968, encodeId=59283596846, content=不错。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sun Aug 23 00:20:00 CST 2015, time=2015-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413431, encodeId=2e6b14134317c, content=<a href='/topic/show?id=3f225299942' target=_blank style='color:#2F92EE;'>#患癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52999, encryptionId=3f225299942, topicName=患癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b2c2959841, createdName=zzc2212, createdTime=Sat Aug 22 10:40:00 CST 2015, time=2015-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601354, encodeId=e83316013540d, content=<a href='/topic/show?id=5baa5299111' target=_blank style='color:#2F92EE;'>#患癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52991, encryptionId=5baa5299111, topicName=患癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat Aug 22 10:40:00 CST 2015, time=2015-08-22, status=1, ipAttribution=)]
    2015-08-22 zhaojie88

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