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PLoS One:发现一种可遏制癌细胞转移的基因

2015-02-17 新华 新华网

日本名古屋市立大学的一个研究小组在新一期的美国在线科学杂志《公共科学图书馆综合卷》上报告说,他们发现人体内一种基因拥有遏制癌细胞转移的功能,这将有助于弄清癌细胞转移的机制并开发出新药。 该校研究生院教授今川正良率领的研究小组注意到,一种名为“fad104”的基因与细胞移动等有关,因此通过实验调查了其是否与癌细胞的转移有关。该基因能促进脂肪细胞分化,在肺的形成过程中,还对II型肺泡

癌细胞

日本名古屋市立大学的一个研究小组在新一期的美国在线科学杂志《公共科学图书馆综合卷》上报告说,他们发现人体内一种基因拥有遏制癌细胞转移的功能,这将有助于弄清癌细胞转移的机制并开发出新药。

该校研究生院教授今川正良率领的研究小组注意到,一种名为“fad104”的基因与细胞移动等有关,因此通过实验调查了其是否与癌细胞的转移有关。该基因能促进脂肪细胞分化,在肺的形成过程中,还对II型肺泡上皮细胞的分化和成熟以及骨骼的形成等发挥重要作用。

研究小组发现,癌细胞会借助血管等在体内移动。研究人员对人类恶性黑色素瘤的癌细胞进行处理,减弱了其中“fad104”基因的功能后发现,癌细胞更容易进入实验鼠的血管。相反,如果强化癌细胞中“fad104”基因的功能,并将这种癌细胞注射到实验鼠尾部,癌细胞向肺部的转移则急剧减少。

研究小组指出,这一发现促进了对癌细胞转移分子机制的认识,并有助于推动开发新的治疗药物。

原始出处:

Katoh D1, Nishizuka M1, Osada S1, Imagawa M1.Fad104, a Positive Regulator of Adipocyte Differentiation, Suppresses Invasion and Metastasis of Melanoma Cells by Inhibition of STAT3 Activity.PLoS One. 2015 Feb 11;10(2):e0117197. doi: 10.1371/journal.pone.0117197. eCollection 2015.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1789643, encodeId=d5b61e896432d, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Sep 07 12:16:00 CST 2015, time=2015-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23697, encodeId=467b2369e7a, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:29:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23676, encodeId=5e97236e6a5, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:25:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16570, encodeId=e04d165e0dd, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Fri Feb 20 09:13:00 CST 2015, time=2015-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16557, encodeId=bf011655eff, content=?学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Thu Feb 19 23:30:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252020, encodeId=36501252020e3, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455897, encodeId=b1d5145589e57, content=<a href='/topic/show?id=2920e8036d8' target=_blank style='color:#2F92EE;'>#细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78036, encryptionId=2920e8036d8, topicName=细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3415750271, createdName=zz72, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595901, encodeId=f1851595901a7, content=<a href='/topic/show?id=bdcfe153376' target=_blank style='color:#2F92EE;'>#癌细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71533, encryptionId=bdcfe153376, topicName=癌细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=365518309389, createdName=yinhl1984, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16378, encodeId=ab6f163e832, content=Good, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Wed Feb 18 17:42:00 CST 2015, time=2015-02-18, status=1, ipAttribution=)]
    2015-05-16 ljjj1053

    很不错学习了

    0

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    2015-05-16 ljjj1053

    很不错学习了

    0

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    2015-02-20 orthoW

    很不错

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1789643, encodeId=d5b61e896432d, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Sep 07 12:16:00 CST 2015, time=2015-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23697, encodeId=467b2369e7a, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:29:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23676, encodeId=5e97236e6a5, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:25:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16570, encodeId=e04d165e0dd, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Fri Feb 20 09:13:00 CST 2015, time=2015-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16557, encodeId=bf011655eff, content=?学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Thu Feb 19 23:30:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252020, encodeId=36501252020e3, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455897, encodeId=b1d5145589e57, content=<a href='/topic/show?id=2920e8036d8' target=_blank style='color:#2F92EE;'>#细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78036, encryptionId=2920e8036d8, topicName=细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3415750271, createdName=zz72, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595901, encodeId=f1851595901a7, content=<a href='/topic/show?id=bdcfe153376' target=_blank style='color:#2F92EE;'>#癌细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71533, encryptionId=bdcfe153376, topicName=癌细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=365518309389, createdName=yinhl1984, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16378, encodeId=ab6f163e832, content=Good, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Wed Feb 18 17:42:00 CST 2015, time=2015-02-18, status=1, ipAttribution=)]
    2015-02-19 orthoW

    ?学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1789643, encodeId=d5b61e896432d, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Sep 07 12:16:00 CST 2015, time=2015-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23697, encodeId=467b2369e7a, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:29:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23676, encodeId=5e97236e6a5, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:25:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16570, encodeId=e04d165e0dd, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Fri Feb 20 09:13:00 CST 2015, time=2015-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16557, encodeId=bf011655eff, content=?学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Thu Feb 19 23:30:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252020, encodeId=36501252020e3, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455897, encodeId=b1d5145589e57, content=<a href='/topic/show?id=2920e8036d8' target=_blank style='color:#2F92EE;'>#细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78036, encryptionId=2920e8036d8, topicName=细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3415750271, createdName=zz72, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595901, encodeId=f1851595901a7, content=<a href='/topic/show?id=bdcfe153376' target=_blank style='color:#2F92EE;'>#癌细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71533, encryptionId=bdcfe153376, topicName=癌细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=365518309389, createdName=yinhl1984, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16378, encodeId=ab6f163e832, content=Good, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Wed Feb 18 17:42:00 CST 2015, time=2015-02-18, status=1, ipAttribution=)]
    2015-02-19 yxch36
  7. [GetPortalCommentsPageByObjectIdResponse(id=1789643, encodeId=d5b61e896432d, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Sep 07 12:16:00 CST 2015, time=2015-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23697, encodeId=467b2369e7a, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:29:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23676, encodeId=5e97236e6a5, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:25:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16570, encodeId=e04d165e0dd, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Fri Feb 20 09:13:00 CST 2015, time=2015-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16557, encodeId=bf011655eff, content=?学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Thu Feb 19 23:30:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252020, encodeId=36501252020e3, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455897, encodeId=b1d5145589e57, content=<a href='/topic/show?id=2920e8036d8' target=_blank style='color:#2F92EE;'>#细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78036, encryptionId=2920e8036d8, topicName=细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3415750271, createdName=zz72, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595901, encodeId=f1851595901a7, content=<a href='/topic/show?id=bdcfe153376' target=_blank style='color:#2F92EE;'>#癌细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71533, encryptionId=bdcfe153376, topicName=癌细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=365518309389, createdName=yinhl1984, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16378, encodeId=ab6f163e832, content=Good, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Wed Feb 18 17:42:00 CST 2015, time=2015-02-18, status=1, ipAttribution=)]
    2015-02-19 zz72
  8. [GetPortalCommentsPageByObjectIdResponse(id=1789643, encodeId=d5b61e896432d, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Sep 07 12:16:00 CST 2015, time=2015-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23697, encodeId=467b2369e7a, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:29:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23676, encodeId=5e97236e6a5, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:25:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16570, encodeId=e04d165e0dd, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Fri Feb 20 09:13:00 CST 2015, time=2015-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16557, encodeId=bf011655eff, content=?学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Thu Feb 19 23:30:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252020, encodeId=36501252020e3, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455897, encodeId=b1d5145589e57, content=<a href='/topic/show?id=2920e8036d8' target=_blank style='color:#2F92EE;'>#细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78036, encryptionId=2920e8036d8, topicName=细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3415750271, createdName=zz72, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595901, encodeId=f1851595901a7, content=<a href='/topic/show?id=bdcfe153376' target=_blank style='color:#2F92EE;'>#癌细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71533, encryptionId=bdcfe153376, topicName=癌细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=365518309389, createdName=yinhl1984, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16378, encodeId=ab6f163e832, content=Good, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Wed Feb 18 17:42:00 CST 2015, time=2015-02-18, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1789643, encodeId=d5b61e896432d, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Mon Sep 07 12:16:00 CST 2015, time=2015-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23697, encodeId=467b2369e7a, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:29:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23676, encodeId=5e97236e6a5, content=很不错学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Sat May 16 19:25:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16570, encodeId=e04d165e0dd, content=很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Fri Feb 20 09:13:00 CST 2015, time=2015-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16557, encodeId=bf011655eff, content=?学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Thu Feb 19 23:30:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252020, encodeId=36501252020e3, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455897, encodeId=b1d5145589e57, content=<a href='/topic/show?id=2920e8036d8' target=_blank style='color:#2F92EE;'>#细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78036, encryptionId=2920e8036d8, topicName=细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3415750271, createdName=zz72, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595901, encodeId=f1851595901a7, content=<a href='/topic/show?id=bdcfe153376' target=_blank style='color:#2F92EE;'>#癌细胞转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71533, encryptionId=bdcfe153376, topicName=癌细胞转移)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=365518309389, createdName=yinhl1984, createdTime=Thu Feb 19 01:16:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16378, encodeId=ab6f163e832, content=Good, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Wed Feb 18 17:42:00 CST 2015, time=2015-02-18, status=1, ipAttribution=)]
    2015-02-18 dearluodi

    Good

    0

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新西兰马拉格汉研究中心的迈克·贝里奇教授(Mike Berridge)领导的小组是世界上第一个发现线粒体DNA能在动物肿瘤细胞间移动的团队。他们的文章上周发表在《细胞》杂志的子刊《细胞-代谢》(Cell Metabolism)上。 “在除复制过程以外的时间里,高等生物的基因通常被认为是受限在胞内的。我们的发现颠覆了这一学说。事实上,线粒体基因在不同细胞之间的传递可能是一个普遍的生物现象。”贝里奇

绿茶或可杀死口腔内癌细胞

据英国《每日邮报》2月4日报道,经研究发现,绿茶中所含的混合物可杀死口腔癌细胞,而健康细胞不受影响。人们都知道喝绿茶可以抵抗疾病。科学家们正在研究研究其原因,确认破坏癌细胞的物质,从而找到治疗口腔癌的以及其他疾病的办法。 美国宾夕法尼亚大学的科学家们对绿茶混合物如何瞄准病变细胞进行了详细探索。早期研究表明绿茶中的混合物表没食子儿茶素没食子酸酯(简称EGCG)可杀死口腔癌细胞,而健康细胞不受影响。

科学家全新发现:注射细菌杀灭癌细胞!

近日,在好莱坞举办的年度临床介入肿瘤学研讨会上,来自Anderson癌症研究中心的研究人员通过研究揭示了,利用细菌或许可以帮助治疗癌症。研究人员将一种名为诺维氏芽孢杆菌-NT(Clostridium novyi-NT)的细菌的孢子注射入6位病人机体的肿瘤中,随后细菌就可以在肿瘤中生长并且杀灭癌细胞。 诺维氏芽孢杆菌-NT生活在土壤中,其和引发食物中毒的芽孢杆菌非常相似,在将诺维氏芽孢杆菌-NT注

PLoS Biol:特殊蛋白质如何杀灭癌细胞

可食用的平菇往往有着神奇的一面,它们可以通过一种特殊的蛋白“吃掉”蜘蛛和线虫;然而我们机体的免疫系统也有特殊的一面,通过破坏感染性细胞、癌细胞及细菌来保护机体不受侵害。近日,一篇发表于国际杂志PLoS Biology上的研究论文中,来自澳洲莫纳斯大学的研究人员通过研究揭示了免疫细胞保护机体不为人知的一面。 利用同步加速器和低温电子显微检查技术,研究者对名为侧耳溶血素(pleurotolysin)

注射细菌可杀灭癌细胞?

近日,在好莱坞举办的年度临床介入肿瘤学研讨会上,来自Anderson癌症研究中心的研究人员通过研究揭示了,利用细菌或许可以帮助治疗癌症。研究人员将一种名为诺维氏芽孢杆菌-NT(Clostridium novyi-NT)的细菌的孢子注射入6位患者机体的肿瘤中,随后细菌就可以在肿瘤中生长并且杀灭癌细胞。 诺维氏芽孢杆菌-NT生活在土壤中,其和引发食物中毒的芽孢杆菌非常相似,在将诺维氏芽

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