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PLOS ONE:青少年妊娠期体重增加与新生儿健康的关系

2018-07-14 海北 MedSci原创

医学研究所(IOM)的妊娠期体重增加建议是基于体重指数(BMI)状态的,使用所有年龄段女性的成人截止点,但是对于青少年有特定的标准,如世界卫生组织(WHO)和疾病预防控制中心(IMO)的标准,因此青少年可能获得不充分的体重增加建议。

医学研究所(IOM)的妊娠期体重增加建议是基于体重指数(BMI)状态的,使用所有年龄段女性的成人截止点,但是对于青少年有特定的标准,如世界卫生组织(WHO)和疾病预防控制中心(IMO)的标准,因此青少年可能获得不充分的体重增加建议。
最近,研究人员估计怀孕前BMI状况的三个标准(WHO,CDC和IOM)之间的分类差异比例,并根据使用三个标准的孕前BMI的体重增加推荐来分析新生儿结局。
这是一项在怀孕青少年中的随访研究。研究人员获得了社会人口统计学,人体测量学和妊娠数据。怀孕前BMI分类差异的百分比是在三个标准之间计算的。根据IOM,妊娠期体重增加分为足够,低和高。回归模型用于分析负新生儿结果。
该研究共包括601名怀孕青少年,平均年龄为16±1.4岁。对于孕前BMI分类,使用IOM与WHO相比,28.5%具有分类差异,而在比较IOM与CDC时,具有分类差异的比例为14%。随着BMI的增加,观察到更大的分类差异。
当使用WHO类别时,体重增加较高与体重较轻的婴儿的风险增加有关(OR:1.91,95% CI:1.03-3.53)。对于CDC标准,低体重增加与早产儿的风险增加相关(OR:2.65; 95% CI:1.16-6.08),高体重增加与低出生体重有关(OR:2.10; 95% CI:1.10-4.01)。对于IOM标准,体重增加低或高与低出生体重和早产的风险增加有关。
与成人标准相比,使用青少年标准存在孕前BMI分类差异。然而,根据世卫组织和疾病预防控制中心的标准,只有高妊娠期体重增加才有可能导致新生儿阴性结果。重要的是为青少年建立BMI分类系统,以更好地预测新生儿结局。

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