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JAHA:与消防员职责所致心源性死亡相关的病理解剖学结果

2018-09-05 xing.T MedSci原创

由此可见,大多数心脏病死亡个体有证据表明存在冠心病和心脏质量增加,并且每种疾病都与心脏病死亡风险显著升高有关。应考虑有针对性地筛查冠心病、增加的心脏质量和既往心肌梗死的证据,以减少消防员发生与职责相关的心源性死亡。

心脏猝死在美国消防员中与职务相关死亡的人数中占最大比例。需要更多地了解心源性猝死的病理原因以及与潜在心脏病相关的风险,以制定基于证据的筛查建议。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,这项回顾性病例对照研究使用了1999年至2014年期间发生的与职务相关消防员死亡的尸检数据,并对心脏相关原因死亡的18至65岁男性消防员与非心脏创伤相关死亡者的心脏检查结果进行了比较。

研究人员分析了276例心脏病例和351例非心脏创伤对照者的数据。在心脏病例中,最常见的(82%)潜在病理性机制是合并的冠心病和心脏肥大/左心室肥大。心脏相关患者心脏肥大(心脏重量>450g)、左心室肥厚(左心室壁厚度≥1.2cm)和严重的冠状动脉狭窄(≥75%)的发生率高于创伤对照组(所有P<0.001)。在多变量分析中,心脏重量>450g、冠状动脉狭窄≥75%,以及既往心肌梗死的证据是心脏死亡强有力的独立预测因子,比值比分别为6.1(95%可信区间为3.6-10.4)、9.3(95%置信区间为5.3-16.1)和6.2(95%置信区间为3.4-11.3)。

由此可见,大多数心脏病死亡个体有证据表明存在冠心病和心脏质量增加,并且每种疾病都与心脏病死亡风险显著升高有关。应考虑有针对性地筛查冠心病、增加的心脏质量和既往心肌梗死的证据,以减少消防员发生与职责相关的心源性死亡。

原始出处:

Denise L. Smith.et al. Pathoanatomic Findings Associated With Duty‐Related Cardiac Death in US Firefighters: A Case–Control Study.JAHA.2018. https://www.ahajournals.org/doi/full/10.1161/JAHA.118.009446

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    2018-09-07 zhaohui6731
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    2018-09-07 mhm295
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    2018-09-06 一一一多

    学习学习

    0

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    2018-09-05 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

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