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Diabetes:糖尿病对脑卒中患者大脑皮层功能的影响!

2017-03-22 xing.T MedSci原创

这些结果表明糖尿病卒中后损伤侧皮质兴奋性的改变缺失,这表明受损的神经可塑性能力在这个大脑半球是一个“双重打击”现象的后果,因为在非卒中糖尿病患者皮质功能已经存在的改变。卒中后依赖损伤对侧皮质的重组可能会影响糖尿病患者脑卒中后的恢复。

糖尿病会损伤神经可塑性的能力,因此患者会经历一个缓慢和较差的卒中后恢复。近日,糖尿病领域权威杂志Diabetes上发表了一篇研究文章。该研究旨在探讨糖尿病卒中患者的皮质功能的变化,以确定这种合并症可能怎样影响脑卒中后皮质可塑性,从而促进功能恢复。

从一个57名参与者的队列中,阈值跟踪经颅磁刺激被用来评估7个糖尿病患者脑卒中后同侧和对侧半球皮质功能,并与12例脑卒中没有糖尿病的患者相比较。研究人员也评估了8例糖尿病无脑卒中患者和30例正常对照者的皮质功能。急性脑卒中后,与正常对照者相比,非糖尿病脑卒中患者的短间隔皮质内抑制(SICI)双侧运动皮层减少,而糖尿病脑卒中患者的SICI仅对侧运动皮层减少,但同侧不减少,相比于糖尿病对照者。此外,糖尿病对照者SICI显著降低,相比于正常对照者。

这些结果表明糖尿病卒中后损伤侧皮质兴奋性的改变缺失,这表明受损的神经可塑性能力在这个大脑半球是一个“双重打击”现象的后果,因为在非卒中糖尿病患者皮质功能已经存在的改变。卒中后依赖损伤对侧皮质的重组可能会影响糖尿病患者脑卒中后的恢复。

原始出处

William Huynh, et al. The Effect of Diabetes on Cortical Function in Stroke: Implications for Post-Stroke Plasticity..Diabetes 2017 Mar.https://doi.org/10.2337/db16-0961

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  6. 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  7. 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content=学习了增加知识了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu Mar 23 10:33:36 CST 2017, time=2017-03-23, status=1, ipAttribution=)]
    2017-03-24 1e10c84am36(暂无匿称)

    文章很好,值得分享

    0

  8. 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style='color:#2F92EE;'>#大脑皮层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43940, encryptionId=95dc4394037, topicName=大脑皮层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b93918842147, createdName=bettycmoon, createdTime=Fri Mar 24 13:49:00 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182372, encodeId=aed21823e271, content=文章很好,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Mar 24 09:37:22 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182299, encodeId=6c2418229938, content=谢谢啦,学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b5f2039852, createdName=嘿嘿哈哈嗯, createdTime=Fri Mar 24 02:25:18 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182294, encodeId=3f33182294c7, content=很好的文章,值得分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Fri Mar 24 01:03:55 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182150, encodeId=0080182150e0, content=学习了增加知识了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu Mar 23 10:33:36 CST 2017, time=2017-03-23, status=1, ipAttribution=)]
    2017-03-24 嘿嘿哈哈嗯

    谢谢啦,学习一下

    0

  9. 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style='color:#2F92EE;'>#大脑皮层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43940, encryptionId=95dc4394037, topicName=大脑皮层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b93918842147, createdName=bettycmoon, createdTime=Fri Mar 24 13:49:00 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182372, encodeId=aed21823e271, content=文章很好,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Mar 24 09:37:22 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182299, encodeId=6c2418229938, content=谢谢啦,学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b5f2039852, createdName=嘿嘿哈哈嗯, createdTime=Fri Mar 24 02:25:18 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182294, encodeId=3f33182294c7, content=很好的文章,值得分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Fri Mar 24 01:03:55 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182150, encodeId=0080182150e0, content=学习了增加知识了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu Mar 23 10:33:36 CST 2017, time=2017-03-23, status=1, ipAttribution=)]
    2017-03-24 明天会更好!

    很好的文章,值得分享!!

    0

  10. 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style='color:#2F92EE;'>#大脑皮层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43940, encryptionId=95dc4394037, topicName=大脑皮层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b93918842147, createdName=bettycmoon, createdTime=Fri Mar 24 13:49:00 CST 2017, time=2017-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182372, encodeId=aed21823e271, content=文章很好,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Mar 24 09:37:22 CST 2017, time=2017-03-24, status=1, ipAttribution=), 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content=学习了增加知识了谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu Mar 23 10:33:36 CST 2017, time=2017-03-23, status=1, ipAttribution=)]
    2017-03-23 大爰

    学习了增加知识了谢谢!

    0

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