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Sleep:睡眠呼吸暂停与男性卒中风险的关系

2016-03-06 MedSci MedSci原创

目的男士若出现睡眠呼吸障碍(SDB)导致夜间血氧不足、睡眠不足,则他们卒中的风险增加。该研究的目的在于探究老年SDB男性发生卒中的风险。 方法2872名生活在小区的老年男性参与研究,他们平均年龄为76岁。研究人员在美国6个临床医院进行实验,并从2003年-2005年收集数据,且使用夜间多导睡眠图测量参与者阻塞性通气指数、低通气指数、中枢呼吸暂停指数和夜间低氧血症发生率等数据信息。平均随访时长为7.

目的

男士若出现睡眠呼吸障碍(SDB)导致夜间血氧不足、睡眠不足,则他们卒中的风险增加。该研究的目的在于探究老年SDB男性发生卒中的风险。

方法

2872名生活在小区的老年男性参与研究,他们平均年龄为76岁。研究人员在美国6个临床医院进行实验,并从2003年-2005年收集数据,且使用夜间多导睡眠图测量参与者阻塞性通气指数、低通气指数、中枢呼吸暂停指数和夜间低氧血症发生率等数据信息。平均随访时长为7.3年。

结果

156名老人(5.4%)在随访时间内出现卒中。调整年龄、诊所地点、种族、BMI和吸烟状况等因素后,研究人员发现,相比没有夜间低氧血症的老人而言,有严重夜间低氧血症(SpO2<90%的夜晚数目超过10%)的老人发生卒中的风险增加1.8倍(相对风险=1.83;95%CI:1.12-2.98;P=0.02)。进一步调整男士卒中病史和其他变量后结论依旧成立。

结论

研究表明,有严重夜间低氧血症的老人出现卒中的风险显著增加。为老人检测夜间血氧饱和度比检测呼吸频率有助于更好地识别老年人卒中的风险。

原始出处:

Sleep Disordered Breathing and Risk of Stroke in Older Community-Dwelling Men,Katie L. Stone,et al,Mar,1,2016


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    2016-04-13 Wechat4343a314

    应该可信

    0

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    2016-03-08 飞翔的笨鸟

    学习了新知识

    0

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