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J Biomed Mater Res B Appl Biomater：种植4年失败，氧化锆植体周围的骨组织学分析

2019-01-02 MedSci MedSci原创

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评估骨组织对从人体取回的表面改性氧化锆植体的反应。29个一段式氧化锆植体显示出边缘骨丢失的持续性增加，并且对治疗没有反应。使用环钻针移除后，对其中22个植体进行骨活组织检查，立即浸入福尔马林中两周。随后，回收的样本进行组织学准备，并对骨整合区域进行骨-植入物接触（BIC）和骨密度的检测。所有移除的植体原位平均植入47.7个月。移除后，可在顶端区域观察到致密骨。附着在植体上的剩余骨包含具有骨和骨细胞

评估骨组织对从人体取回的表面改性氧化锆植体的反应。

29个一段式氧化锆植体显示出边缘骨丢失的持续性增加，并且对治疗没有反应。使用环钻针移除后，对其中22个植体进行骨活组织检查，立即浸入福尔马林中两周。随后，回收的样本进行组织学准备，并对骨整合区域进行骨-植入物接触（BIC）和骨密度的检测。

所有移除的植体原位平均植入47.7个月。移除后，可在顶端区域观察到致密骨。附着在植体上的剩余骨包含具有骨和骨细胞的规则层状结构。BIC范围为58.1％至93.7％（平均值：76.5％），植体螺纹内的骨面积/密度范围为57％至97.2％（平均值：84.8％）。

表明多孔氧化锆植体在骨骼仍附着的区域显示出足够的BIC。尽管由于骨质丧失增加而必须移除植体，但氧化锆植体表面本身似乎具有较好的骨整合效果。

原始出处：

Kohal RJ, Schwindling FS, et al., Peri-implant bone response to retrieved human zirconia oral implants after a 4-year loadingperiod: A histologic and histomorphometric evaluation of 22 cases. J Biomed Mater Res B Appl Biomater. 2016 Nov;104(8):1622-1631. doi: 10.1002/jbm.b.33512. Epub 2015 Aug 31.

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    2019-04-30 huangdf

    #种植#

    0

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    2019-01-30 bnurmamat

    #组织学#

    0

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    2019-10-16 sunylz

    #Bio#

    0

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    2019-02-04 diushouji

    #骨组织#

    0

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    2019-11-29 119337457

    #组织学分析#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1702048, encodeId=a3741e0204857, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Tue Apr 30 21:36:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926249, encodeId=3d391926249f2, content=<a href='/topic/show?id=9238e767680' target=_blank style='color:#2F92EE;'>#组织学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77676, encryptionId=9238e767680, topicName=组织学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Wed Jan 30 21:36:00 CST 2019, time=2019-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918452, encodeId=1f151918452fe, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 16 10:36:00 CST 2019, time=2019-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076354, encodeId=d9fd20e635468, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Feb 04 19:36:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804847, encodeId=14cf180484e13, content=<a href='/topic/show?id=175fe767713' target=_blank style='color:#2F92EE;'>#组织学分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77677, encryptionId=175fe767713, topicName=组织学分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Nov 29 17:36:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459729, encodeId=db021459e29d1, content=<a href='/topic/show?id=00da63996ea' target=_blank style='color:#2F92EE;'>#氧化锆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63996, encryptionId=00da63996ea, topicName=氧化锆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=facd6195692, createdName=medsci248, createdTime=Fri Jan 04 12:36:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609449, encodeId=6c1f16094495e, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Jan 04 12:36:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=357020, encodeId=0acb35e020f9, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Wed Jan 02 22:45:24 CST 2019, time=2019-01-02, status=1, ipAttribution=)]
    2019-01-04 medsci248

    #氧化锆#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1702048, encodeId=a3741e0204857, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Tue Apr 30 21:36:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926249, encodeId=3d391926249f2, content=<a href='/topic/show?id=9238e767680' target=_blank style='color:#2F92EE;'>#组织学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77676, encryptionId=9238e767680, topicName=组织学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Wed Jan 30 21:36:00 CST 2019, time=2019-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918452, encodeId=1f151918452fe, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 16 10:36:00 CST 2019, time=2019-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076354, encodeId=d9fd20e635468, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Feb 04 19:36:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804847, encodeId=14cf180484e13, content=<a href='/topic/show?id=175fe767713' target=_blank style='color:#2F92EE;'>#组织学分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77677, encryptionId=175fe767713, topicName=组织学分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Nov 29 17:36:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459729, encodeId=db021459e29d1, content=<a href='/topic/show?id=00da63996ea' target=_blank style='color:#2F92EE;'>#氧化锆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63996, encryptionId=00da63996ea, topicName=氧化锆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=facd6195692, createdName=medsci248, createdTime=Fri Jan 04 12:36:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609449, encodeId=6c1f16094495e, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Jan 04 12:36:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=357020, encodeId=0acb35e020f9, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Wed Jan 02 22:45:24 CST 2019, time=2019-01-02, status=1, ipAttribution=)]
    2019-01-04 ms3994565386320060

    #Med#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1702048, encodeId=a3741e0204857, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Tue Apr 30 21:36:00 CST 2019, time=2019-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926249, encodeId=3d391926249f2, content=<a href='/topic/show?id=9238e767680' target=_blank style='color:#2F92EE;'>#组织学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77676, encryptionId=9238e767680, topicName=组织学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Wed Jan 30 21:36:00 CST 2019, time=2019-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918452, encodeId=1f151918452fe, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed Oct 16 10:36:00 CST 2019, time=2019-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2076354, encodeId=d9fd20e635468, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Feb 04 19:36:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804847, encodeId=14cf180484e13, content=<a href='/topic/show?id=175fe767713' target=_blank style='color:#2F92EE;'>#组织学分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77677, encryptionId=175fe767713, topicName=组织学分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Fri Nov 29 17:36:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1459729, encodeId=db021459e29d1, content=<a href='/topic/show?id=00da63996ea' target=_blank style='color:#2F92EE;'>#氧化锆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63996, encryptionId=00da63996ea, topicName=氧化锆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=facd6195692, createdName=medsci248, createdTime=Fri Jan 04 12:36:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609449, encodeId=6c1f16094495e, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Jan 04 12:36:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=357020, encodeId=0acb35e020f9, content=认真学习，不断进步，把经验分享给同好。点赞了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Wed Jan 02 22:45:24 CST 2019, time=2019-01-02, status=1, ipAttribution=)]
    2019-01-02 lietome2

    认真学习，不断进步，把经验分享给同好。点赞了！

    0

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