Circulation：吸烟与心力衰竭！

2018-04-16 xing.T MedSci原创

由此可见，在黑人中，调整了冠心病的影响，吸烟是左室肥厚、收缩功能障碍和因心衰住院的重要危险因素。

吸烟与心功能不全的一些因素有关。近日，心血管领域权威杂志Circulation上发表了一篇研究文章，研究人员假设吸烟与左心室（LV）结构和功能以及心力衰竭住院有关。

在杰克逊心脏研究中，研究人员调查了4129名（从不吸烟者n=2884，当前吸烟者n=503，以及既往吸烟者n=742）没有心衰或冠心病病史的黑人参与者（平均年龄为54岁，63%为女性）。研究人员在1092名参与者中评估了吸烟与通过心脏磁共振成像检查的左心室结构和功能之间的关系，以及在3325名参与者中评估了吸烟与脑钠肽水平之间的关系，并在3633名完整数据的参与者中评估了心衰住院率。

在调整混杂因素后，与不吸烟者相比，当前吸烟与较大的平均左室质量指数和较低的平均LV环周应变（P＜0.05）有关。吸烟状况、强度和负担与较高的平均脑钠肽水平有关（所有P＜0.05）。平均随访8年（7.7-8.0）期间，有147例受试者因心衰住院。将传统的危险因素以及冠心病事件调整后，与不吸烟者相比，当前吸烟（风险比为2.82；95%可信区间为1.71-4.64）、目前吸烟者的吸烟强度（≥20支/天：风险比为3.48；95%可信区间为1.65-7.32）、既往吸烟者的吸烟负担（≥15包年：风险比为2.06；95%可信区间为1.29-3.3）与心衰住院治疗显著相关。

由此可见，在黑人中，调整了冠心病的影响，吸烟是左室肥厚、收缩功能障碍和因心衰住院的重要危险因素。

原始出处：

Daisuke Kamimura,et al. Cigarette Smoking and Incident Heart Failure: Insights From the Jackson Heart Study. Circulation. 2018. https://doi.org/10.1161/CIRCULATIONAHA.117.031912

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[GetPortalCommentsPageByObjectIdResponse(id=306924, encodeId=0cfe30692430, content=这个毋庸置疑.吸烟还可引起血管的改变.从而导致心脏缺血.心肌功能的损害等等, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d96e2039706, createdName=lineenil, createdTime=Wed Apr 18 10:15:09 CST 2018, time=2018-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306781, encodeId=b6a4306e818e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=577e1645582, createdName=yaoran2008, createdTime=Wed Apr 18 04:59:39 CST 2018, time=2018-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306583, encodeId=863d30658321, content=研究数据不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff272028996, createdName=心驰, createdTime=Tue Apr 17 07:17:49 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306574, encodeId=c86b3065e46f, content=好文献.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Tue Apr 17 07:04:54 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306484, encodeId=62a7306484e7, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Tue Apr 17 05:05:47 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306451, encodeId=07933064519e, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Apr 16 23:43:03 CST 2018, time=2018-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306436, encodeId=59fb30643654, content=学习了.长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Apr 16 23:24:11 CST 2018, time=2018-04-16, status=1, ipAttribution=)]
2018-04-18 lineenil

这个毋庸置疑.吸烟还可引起血管的改变.从而导致心脏缺血.心肌功能的损害等等

121 0
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2018-04-18 yaoran2008

学习了

130 0
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2018-04-17 心驰

研究数据不错

110 0
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2018-04-17 张新亮1853311252142e2fm

好文献.学习了

122 0
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2018-04-17 秀红

学习了

125 0
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2018-04-16 清风拂面

谢谢分享学习

87 0
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2018-04-16 1ddf0692m34(暂无匿称)

学习了.长知识

81 0

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