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Neurology:卒中和TIA后睡眠呼吸紊乱的患病率

2019-01-12 xing.T MedSci原创

随着时间的推移,卒中和TIA后SDB的高患病率仍然持续存在,因为根据最近的研究报告了在该临床环境中SDB治疗的可行性和疗效。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员旨在对卒中后睡眠呼吸障碍(SDB)的患病率进行系统评价和荟萃分析。

研究人员检索了PubMed、Embase(Ovid)、Cochrane图书馆和CINAHL(检索日期从数据库成立至2017年4月7日),查找了报道了卒中或TIA后SDB患病率和/或严重程度的临床研究。只有使用美国睡眠医学学会I-IV类的全多导睡眠图和诊断设备进行的睡眠呼吸暂停检测的研究纳入了分析。研究人员进行了随机效应荟萃分析。PROSPERO注册号为CRD42017072339。

初步检索确定了5211项研究,89项研究(包括7096名患者)符合纳入标准。在卒中后(不到1个月)急性期进行了54项研究,在亚急性期(1-3个月后)进行了23项研究,在慢性期(超过3个月后)进行了12项研究。平均呼吸暂停-低通气指数为26.0/h(SD为21.7-31.2)。呼吸暂停低通气指数大于5/h且大于30/h的SDB患病率分别为71%(95%置信区间为66.6%-74.8%)和30%(95%置信区间为24.4%-35.5%)。无论所进行的睡眠呼吸暂停检查的类型如何,在卒中后的所有检查阶段,SDB的严重程度和患病率相似。研究之间的异质性(I2)大多数都很高。

随着时间的推移,卒中和TIA后SDB的高患病率仍然持续存在,因为根据最近的研究报告了在该临床环境中SDB治疗的可行性和疗效。

原始出处:


Andrea Seiler,et al.Prevalence of sleep-disordered breathing after stroke and TIA A meta-analysis.Neurology. 2019.http://n.neurology.org/content/early/2019/01/11/WNL.0000000000006904

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    2019-06-28 yinhl1978
  2. [GetPortalCommentsPageByObjectIdResponse(id=2000678, encodeId=166d20006e899, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Jun 28 00:24:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989117, encodeId=ed69198911eed, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Jun 08 06:24:00 CST 2019, time=2019-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358468, encodeId=911c35846865, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Jan 17 20:23:13 CST 2019, time=2019-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250600, encodeId=5b1112506005a, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Mon Jan 14 03:24:00 CST 2019, time=2019-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026264, encodeId=97171026264a1, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Jan 12 15:24:00 CST 2019, time=2019-01-12, status=1, ipAttribution=)]
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    2019-01-17 wxl882001

    了解一下

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2000678, encodeId=166d20006e899, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Jun 28 00:24:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989117, encodeId=ed69198911eed, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Sat Jun 08 06:24:00 CST 2019, time=2019-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358468, encodeId=911c35846865, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Jan 17 20:23:13 CST 2019, time=2019-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250600, encodeId=5b1112506005a, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Mon Jan 14 03:24:00 CST 2019, time=2019-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026264, encodeId=97171026264a1, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Jan 12 15:24:00 CST 2019, time=2019-01-12, status=1, ipAttribution=)]
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    2019-01-12 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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