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BMC Cancer:胆石症会大大增加肝内胆管癌风险

2015-11-04 Mechront 译 MedSci原创

目前肝内胆管癌 (ICC) 病因并不明确,大部分认可肝内胆管结石会增加ICC风险,那么肝外胆道结石呢?目前众说纷纭,结论并不一致。研究者进行了荟萃分析,探究胆总管结石和胆囊结石与ICC风险间关系。研究者检索了PubMed, Embase, Web of Science等数据库,关于胆总管结石和胆囊结石与ICC风险间关系的队列和病例对照研究。最终该研究纳入了7篇病例对照研究,涉及123,771名参与

目前肝内胆管癌 (ICC) 病因并不明确,大部分认可肝内胆管结石会增加ICC风险,那么肝外胆道结石呢?目前众说纷纭,结论并不一致。研究者进行了荟萃分析,探究胆总管结石和胆囊结石与ICC风险间关系。

研究者检索了PubMed, Embase, Web of Science等数据库,关于胆总管结石和胆囊结石与ICC风险间关系的队列和病例对照研究。

最终该研究纳入了7篇病例对照研究,涉及123,771名参与者,其中4763 (3.85 %)为ICC患者,119,008 名为非癌症对照组患者。研究数据显示,预先存在的胆管结石(胆总管结石或胆总管结石伴肝内胆管结石)会增加ICC风险(OR17.64, 95%CI 11.14-27.95)。单独存在的胆总管结石也会大大增加ICC风险(OR11.79, 95%CI4.17-33.35)。胆囊结石会小幅度的增加ICC风险 (OR 2.00, 95 % CI 1.16-3.42),不过研究间异质性很大(I (2) = 78.5 %)。

研究结果表明,胆管结石包括胆总管结石,是肝内胆管癌的重要的危险因素,临床上应该对胆石症患者提高警惕,进行必要的监测。

原始出处:

Cai H, Kong WT,et al.Cholelithiasis and the risk of intrahepatic cholangiocarcinoma: a meta-analysis of observational studies.BMC Cancer. 2015 Nov 2;15:831.


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    2024-01-17 ms5000000630421490 来自山西省

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    2016-05-08 sjq027
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  4. [GetPortalCommentsPageByObjectIdResponse(id=2182147, encodeId=f3d5218214e15, content=标记, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ffa08580074, createdName=ms5000000630421490, createdTime=Wed Jan 17 10:10:26 CST 2024, time=2024-01-17, status=1, ipAttribution=山西省), GetPortalCommentsPageByObjectIdResponse(id=2061488, encodeId=bc9c206148801, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun May 08 05:54:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935993, encodeId=d1811935993dd, content=<a href='/topic/show?id=37da8349471' target=_blank style='color:#2F92EE;'>#胆石症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83494, encryptionId=37da8349471, topicName=胆石症)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Mon Feb 29 23:54:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974631, encodeId=e09919e463145, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Dec 23 20:54:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74002, encodeId=6114e400271, content=meta分析也能发这么高分的杂志,666, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=109f1616069, createdName=DoctorTao1991, createdTime=Sun Mar 27 18:47:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=43546, encodeId=73e943546dc, content=原来是meta, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cad31998, createdName=dwtouxx, createdTime=Sun Nov 22 10:43:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42679, encodeId=0280426e9f3, content=是篇荟萃分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Nov 06 20:02:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296018, encodeId=ed321296018d1, content=<a href='/topic/show?id=ef11811e363' target=_blank style='color:#2F92EE;'>#肝内胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81173, encryptionId=ef11811e363, topicName=肝内胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb3a261, createdName=liuxiaona, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628256, encodeId=f59d16282561f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2182147, encodeId=f3d5218214e15, content=标记, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ffa08580074, createdName=ms5000000630421490, createdTime=Wed Jan 17 10:10:26 CST 2024, time=2024-01-17, status=1, ipAttribution=山西省), GetPortalCommentsPageByObjectIdResponse(id=2061488, encodeId=bc9c206148801, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun May 08 05:54:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935993, encodeId=d1811935993dd, content=<a href='/topic/show?id=37da8349471' target=_blank style='color:#2F92EE;'>#胆石症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83494, encryptionId=37da8349471, topicName=胆石症)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Mon Feb 29 23:54:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974631, encodeId=e09919e463145, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Dec 23 20:54:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74002, encodeId=6114e400271, content=meta分析也能发这么高分的杂志,666, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=109f1616069, createdName=DoctorTao1991, createdTime=Sun Mar 27 18:47:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=43546, encodeId=73e943546dc, content=原来是meta, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cad31998, createdName=dwtouxx, createdTime=Sun Nov 22 10:43:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42679, encodeId=0280426e9f3, content=是篇荟萃分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Nov 06 20:02:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296018, encodeId=ed321296018d1, content=<a href='/topic/show?id=ef11811e363' target=_blank style='color:#2F92EE;'>#肝内胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81173, encryptionId=ef11811e363, topicName=肝内胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb3a261, createdName=liuxiaona, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628256, encodeId=f59d16282561f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
    2016-03-27 DoctorTao1991

    meta分析也能发这么高分的杂志,666

    0

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    2015-11-22 dwtouxx

    原来是meta

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2182147, encodeId=f3d5218214e15, content=标记, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ffa08580074, createdName=ms5000000630421490, createdTime=Wed Jan 17 10:10:26 CST 2024, time=2024-01-17, status=1, ipAttribution=山西省), GetPortalCommentsPageByObjectIdResponse(id=2061488, encodeId=bc9c206148801, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun May 08 05:54:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935993, encodeId=d1811935993dd, content=<a href='/topic/show?id=37da8349471' target=_blank style='color:#2F92EE;'>#胆石症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83494, encryptionId=37da8349471, topicName=胆石症)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Mon Feb 29 23:54:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974631, encodeId=e09919e463145, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Dec 23 20:54:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74002, encodeId=6114e400271, content=meta分析也能发这么高分的杂志,666, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=109f1616069, createdName=DoctorTao1991, createdTime=Sun Mar 27 18:47:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=43546, encodeId=73e943546dc, content=原来是meta, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cad31998, createdName=dwtouxx, createdTime=Sun Nov 22 10:43:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42679, encodeId=0280426e9f3, content=是篇荟萃分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Nov 06 20:02:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296018, encodeId=ed321296018d1, content=<a href='/topic/show?id=ef11811e363' target=_blank style='color:#2F92EE;'>#肝内胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81173, encryptionId=ef11811e363, topicName=肝内胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb3a261, createdName=liuxiaona, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628256, encodeId=f59d16282561f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
    2015-11-06 jetleo

    是篇荟萃分析

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2182147, encodeId=f3d5218214e15, content=标记, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ffa08580074, createdName=ms5000000630421490, createdTime=Wed Jan 17 10:10:26 CST 2024, time=2024-01-17, status=1, ipAttribution=山西省), GetPortalCommentsPageByObjectIdResponse(id=2061488, encodeId=bc9c206148801, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun May 08 05:54:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935993, encodeId=d1811935993dd, content=<a href='/topic/show?id=37da8349471' target=_blank style='color:#2F92EE;'>#胆石症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83494, encryptionId=37da8349471, topicName=胆石症)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Mon Feb 29 23:54:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974631, encodeId=e09919e463145, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Dec 23 20:54:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74002, encodeId=6114e400271, content=meta分析也能发这么高分的杂志,666, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=109f1616069, createdName=DoctorTao1991, createdTime=Sun Mar 27 18:47:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=43546, encodeId=73e943546dc, content=原来是meta, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cad31998, createdName=dwtouxx, createdTime=Sun Nov 22 10:43:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42679, encodeId=0280426e9f3, content=是篇荟萃分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Nov 06 20:02:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296018, encodeId=ed321296018d1, content=<a href='/topic/show?id=ef11811e363' target=_blank style='color:#2F92EE;'>#肝内胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81173, encryptionId=ef11811e363, topicName=肝内胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb3a261, createdName=liuxiaona, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628256, encodeId=f59d16282561f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=2182147, encodeId=f3d5218214e15, content=标记, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ffa08580074, createdName=ms5000000630421490, createdTime=Wed Jan 17 10:10:26 CST 2024, time=2024-01-17, status=1, ipAttribution=山西省), GetPortalCommentsPageByObjectIdResponse(id=2061488, encodeId=bc9c206148801, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sun May 08 05:54:00 CST 2016, time=2016-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935993, encodeId=d1811935993dd, content=<a href='/topic/show?id=37da8349471' target=_blank style='color:#2F92EE;'>#胆石症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83494, encryptionId=37da8349471, topicName=胆石症)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Mon Feb 29 23:54:00 CST 2016, time=2016-02-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974631, encodeId=e09919e463145, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Dec 23 20:54:00 CST 2015, time=2015-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74002, encodeId=6114e400271, content=meta分析也能发这么高分的杂志,666, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=109f1616069, createdName=DoctorTao1991, createdTime=Sun Mar 27 18:47:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=43546, encodeId=73e943546dc, content=原来是meta, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0cad31998, createdName=dwtouxx, createdTime=Sun Nov 22 10:43:00 CST 2015, time=2015-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42679, encodeId=0280426e9f3, content=是篇荟萃分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Nov 06 20:02:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296018, encodeId=ed321296018d1, content=<a href='/topic/show?id=ef11811e363' target=_blank style='color:#2F92EE;'>#肝内胆管癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81173, encryptionId=ef11811e363, topicName=肝内胆管癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cb3a261, createdName=liuxiaona, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1628256, encodeId=f59d16282561f, content=<a href='/topic/show?id=9a4e83503e4' target=_blank style='color:#2F92EE;'>#胆管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83503, encryptionId=9a4e83503e4, topicName=胆管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c21721182790, createdName=cmj15wellington, createdTime=Fri Nov 06 14:54:00 CST 2015, time=2015-11-06, status=1, ipAttribution=)]

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