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JAHA:妊娠期间晕厥的发生率、时间趋势和结局

2019-05-15 xing.T 网络

由此可见,患有晕厥的孕妇,尤其是在妊娠早期发生晕厥事件时,出现不良妊娠结局的风险增加,以及心律失常和产后晕厥的发生率也增加。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在评估妊娠期间出现晕厥的女性趋势、时间和频率,以及在产后第一年出现的新生儿和产妇的不良结局。

这是一项2005年1月1日至2014年12月31日期间在加拿大艾伯塔省的孕妇中进行的回顾性研究。在481930例孕妇中,有4667例孕妇妊娠期间出现晕厥。泊松回归分析发现年龄校正的晕厥发生率增加5%/年(比率为1.05; 95%CI为1.04-1.06)。

总体而言,1506例(32.3%)孕妇晕厥首发于妊娠中期,2058例(44.1%)孕妇发生在妊娠中期,1103例(23.6%)孕妇发生在妊娠晚期;8%(n=377)的妊娠妇女有>1次晕厥发作。与没有晕厥的女性相比,经历晕厥的女性更年轻(年龄<25岁; 34.7% vs. 20.8%; P<0.001)和初产妇(52.1% vs. 42.4%; P<0.001)。与早期妊娠(15.8%)和妊娠晚期(14.2%)发生晕厥的孕妇以及无晕厥孕妇(15.0%; P<0.01)相比,妊娠早期发生晕厥的孕妇(18.3%)早产几率更高。妊娠期多发性晕厥发作孕妇所生儿童(4.9%)发生先天性异常的几率显著高于无晕厥孕妇所生儿童(2.9%; P<0.01)。分娩后1年内,妊娠期晕厥妇女的心律失常和晕厥发作率高于妊娠期无晕厥的妇女。 

由此可见,患有晕厥的孕妇,尤其是在妊娠早期发生晕厥事件时,出现不良妊娠结局的风险增加,以及心律失常和产后晕厥的发生率也增加。 

原始出处:

Safia Chatur.et al.Incidence of Syncope During Pregnancy: Temporal Trends and Outcomes.JAHA.2019.https://www.ahajournals.org/doi/full/10.1161/JAHA.118.011608

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    2019-05-17 zhaohui6731
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    2019-05-17 lily1616

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