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JACC:空气污染与心脏移植后死亡风险呈相关性

2019-12-13 不详 MedSci原创

接受心脏移植的患者死亡风险较高,传统的风险评分在预测移植后存活率方面表现一般,强调了尚未确定的因素在决定预后方面的重要性。本研究的目的旨在评估PM2.5的暴露与心脏移植死亡风险的相关性。本研究纳入分析了UNOS数据库中的21800名接受了心脏移植的患者,随访时间是86713人年,接受心脏移植时的平均年龄为52.6 ± 12.6岁,男性占75%,白种人占69%,39%有缺血性心力衰竭病因。平均对PM

接受心脏移植的患者死亡风险较高,传统的风险评分在预测移植后存活率方面表现一般,强调了尚未确定的因素在决定预后方面的重要性。本研究的目的旨在评估PM2.5的暴露与心脏移植死亡风险的相关性。

本研究纳入分析了UNOS数据库中的21800名接受了心脏移植的患者,随访时间是86713人年,接受心脏移植时的平均年龄为52.6 ± 12.6岁,男性占75%,白种人占69%,39%有缺血性心力衰竭病因。平均对PM2.5的暴露为10.6 ± 2.3 μg/m3。经过平均4.8年时间的随访,有5208名(23.9%)患者出现死亡,PM2.5的暴露每增加10 μg/m3,患者的死亡风险会增加1.43(95% Cl:1.21-1.49),且这种相关性在各亚组之间是一致的。

研究结果显示,空气污染与心脏移植后的死亡风险呈相关性。

原始出处:

本文系梅斯医学(MedSci)原创编译整理,转载需授权


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    2020-06-27 hbwxf
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    2019-12-13 dong8372

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