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Am J Prev Med:儿童期不良经历可致成年危险行为及共发病

2015-10-29 phylis 译 MedSci原创

背景:不良儿童体验(ACEs)与早期死亡率与发病率相关。这篇研究评估了ACEs与健康行为高风险及共存病的相关性,及ACE个部分的独立影响作用。方法:分析2011年的行为风险因素检测系统调查美国五个州48526名成人的相关数据。暴露因素包括心理的,身体的及性虐待的形式,及家庭功能障碍如物质滥用,精神疾病,暴力及监禁。主要的预后指标包括危险行为和发病情况:狂欢性饮酒,酗酒,吸烟,高危HIV行为,肥胖,

背景:儿童期不良经历(ACEs)与早期死亡率与发病率相关。这篇研究评估了ACEs与健康行为高风险及共存病的相关性,及ACE个体部分的独立影响作用。

方法:分析2011年的行为风险因素检测系统调查美国五个州48526名成人的相关数据。暴露因素包括心理的、身体的虐待及性虐待的形式,及家庭功能障碍如物质滥用、精神疾病、暴力及监禁。主要的预后指标包括危险行为和发病情况:狂欢式的饮酒、酗酒、吸烟、高危HIV行为、肥胖、糖尿病、心肌梗死、冠心病、卒中、抑郁及因健康状况引起的残疾,和由于残疾特殊设备的使用。应用多元Logistic回归分析评估ACE分数和危险行为/共发病的相关性,并且控制协变量后,评估各个ACE元素与危险行为/共发病的关系。

结果:54%的受试者经历过至少一次的儿童期不良经历,13.7的受试者经历过四次甚至更多儿童期不良经历。ACE大于等于4与狂欢式的饮酒、酗酒、抽烟、高危HIV行为、糖尿病、心肌梗死、冠心病、卒中、抑郁及因健康状况引起的残疾,和由于残疾特殊设备的使用相关。另外,不同的ACE对危险行为和共发病有着不同的作用。

结论:控制混杂因素后,儿童期不良经历对成人危险行为、发病及残疾有着不同的影响。

原文出处:

Campbell JA, Walker RJ, Egede LE. Associations Between Adverse Childhood Experiences, High-Risk Behaviors, and Morbidity in Adulthood. Am J Prev Med. 2015,Oct 13.


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  1. [GetPortalCommentsPageByObjectIdResponse(id=2080440, encodeId=b4c8208044011, content=<a href='/topic/show?id=6df629993ee' target=_blank style='color:#2F92EE;'>#共发病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29993, encryptionId=6df629993ee, topicName=共发病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2a44345, createdName=yulin2006, createdTime=Sat Feb 20 19:04:00 CST 2016, time=2016-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606685, encodeId=ab23160668558, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Oct 31 07:04:00 CST 2015, time=2015-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41991, encodeId=1e2b41991fc, content=很感兴趣这个怎么做分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Fri Oct 30 21:52:00 CST 2015, time=2015-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41988, encodeId=9a9d41988de, content=嗯,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Fri Oct 30 21:51:00 CST 2015, time=2015-10-30, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2080440, encodeId=b4c8208044011, content=<a href='/topic/show?id=6df629993ee' target=_blank style='color:#2F92EE;'>#共发病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29993, encryptionId=6df629993ee, topicName=共发病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2a44345, createdName=yulin2006, createdTime=Sat Feb 20 19:04:00 CST 2016, time=2016-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606685, encodeId=ab23160668558, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Oct 31 07:04:00 CST 2015, time=2015-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41991, encodeId=1e2b41991fc, content=很感兴趣这个怎么做分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Fri Oct 30 21:52:00 CST 2015, time=2015-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41988, encodeId=9a9d41988de, content=嗯,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Fri Oct 30 21:51:00 CST 2015, time=2015-10-30, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2080440, encodeId=b4c8208044011, content=<a href='/topic/show?id=6df629993ee' target=_blank style='color:#2F92EE;'>#共发病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29993, encryptionId=6df629993ee, topicName=共发病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2a44345, createdName=yulin2006, createdTime=Sat Feb 20 19:04:00 CST 2016, time=2016-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606685, encodeId=ab23160668558, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Oct 31 07:04:00 CST 2015, time=2015-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41991, encodeId=1e2b41991fc, content=很感兴趣这个怎么做分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Fri Oct 30 21:52:00 CST 2015, time=2015-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41988, encodeId=9a9d41988de, content=嗯,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Fri Oct 30 21:51:00 CST 2015, time=2015-10-30, status=1, ipAttribution=)]
    2015-10-30 三三五五

    很感兴趣这个怎么做分析

    0

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    2015-10-30 三三五五

    嗯,好

    0

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