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Obstet Gynecol:45岁以上女性双胎妊娠结局如何?

2017-04-11 xing.T MedSci原创

在超过45岁的双胎妊娠健康妇女人群中,分娩时,这些孕妇剖宫产、先兆子痫和妊娠糖尿病发生率较高,但总体结局良好。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章,研究人员旨在调查45岁以上女性双胎妊娠结局。

这是一项在139名双胎妊娠孕妇中进行的回顾性队列研究,她们分娩时至少45岁。这些参与者于2005年至2016年期间在二级转诊中心接受过治疗。分析包括基础特征和妊娠结局,包括分娩方式、分娩时孕周、妊娠期高血压疾病、妊娠糖尿病和胎儿生长受限。研究人员采用单变量分析评估了患者特征和结局之间的相关性。

产妇平均年龄为47.3±1.9岁,其中99.3%的受试者接受了体外受精,95%的受试者使用供体卵细胞。另外,患者的基础高血压(7.2%)、肥胖(9.5%)和孕前糖尿病(1.4%)发生均较低。分娩时平均孕周为35.4孕周;在妊娠34周之前分娩的占22.3%。剖宫产(93.5%,95%可信区间为87.7-96.8%)、先兆子痫(44.6%,95%可信区间为36.3-53.3%)和妊娠糖尿病(19%,95%可信区间为13.0-26.8%)的发生率较高。50.5%的初产妇发生先兆子痫,而30.5%的孕妇发生早产(P=0.028)。白种人孕妇发生妊娠少于34周的早产儿的几率为18.1%,而非白种人的女性为30.3%(P=0.036)。

在超过45岁的双胎妊娠健康妇女人群中,分娩时,这些孕妇剖宫产、先兆子痫和妊娠糖尿病发生率较高,但总体结局良好。

原始出处:

Gerber, Rachel S, et al. Outcomes of Twin Pregnancies in Women 45 Years of Age or Older.Obstetrics & Gynecology.2017. http://journals.lww.com/greenjournal/Abstract/publishahead/Outcomes_of_Twin_Pregnancies_in_Women_45_Years_of.98447.aspx

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    2017-05-20 zhmscau
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    2017-10-29 yhy100200
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    2017-04-14 wei834766788

    学习了!!!!

    0

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    2017-04-12 lemon985

    大龄的还是不要生太危险

    0

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    2017-04-12 lyh994

    国外与国内差距这么大吗?

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2043952, encodeId=e0b22043952d3, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon May 29 01:43:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2058148, encodeId=0177205814869, content=<a href='/topic/show?id=5e4d1348d5' target=_blank style='color:#2F92EE;'>#45岁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1348, encryptionId=5e4d1348d5, topicName=45岁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e94174, createdName=zhmscau, createdTime=Sat May 20 10:43:00 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011288, encodeId=6d1620112884e, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sun Oct 29 21:43:00 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187345, encodeId=129d18e345c2, content=学习了!!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Fri Apr 14 13:28:33 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392915, encodeId=886e1392915e9, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Thu Apr 13 11:43:00 CST 2017, time=2017-04-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186871, encodeId=ef191868e1f6, content=大龄的还是不要生太危险, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca432042642, createdName=lemon985, createdTime=Wed Apr 12 10:58:06 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186834, encodeId=0c8018683437, content=国外与国内差距这么大吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Wed Apr 12 09:19:27 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186829, encodeId=70701868294a, content=技术进步,高龄双胎也可以搞定。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kym1A9qicflExZYSdibSZBHDyicKZZj37w4jR44fPa9DI3mVLObHAxzntpTAbwxeHvviclcw8coNrDge/0, createdBy=6dc22001775, createdName=春暖花开8785, createdTime=Wed Apr 12 08:48:36 CST 2017, time=2017-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186730, encodeId=1535186e30d7, content=可以怀孕双胞胎,但是注意羊水栓塞症, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Apr 11 21:46:54 CST 2017, time=2017-04-11, status=1, ipAttribution=)]
    2017-04-12 春暖花开8785

    技术进步,高龄双胎也可以搞定。

    0

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    2017-04-11 有备才能无患

    可以怀孕双胞胎,但是注意羊水栓塞症

    0

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