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Lancet:周围动脉疾病已成全球性问题

2013-10-28 高晓方 译 医学论坛网

周围动脉疾病已成为全球性问题 吸烟仍为重要危险因素  英国一项系统综述表明,周围动脉疾病已成为全球性问题;中低收入国家的政府和非政府组织应明确周围动脉疾病的社会和经济影响,并评估最佳的预防和治疗策略。论文于10月19日在线发表于《柳叶刀》(Lancet)。  研究者检索了以踝臂指数(ABI)≤0.90定义周围动脉疾病且以社区为基础的相关文献。利用流行病学模型确定高收入国家(HIC)和中低

周围动脉疾病已成为全球性问题 吸烟仍为重要危险因素
  

英国一项系统综述表明,周围动脉疾病已成为全球性问题;中低收入国家的政府和非政府组织应明确周围动脉疾病的社会和经济影响,并评估最佳的预防和治疗策略。论文于10月19日在线发表于《柳叶刀》(Lancet)。【原文下载】
  
研究者检索了以踝臂指数(ABI)≤0.90定义周围动脉疾病且以社区为基础的相关文献。利用流行病学模型确定高收入国家(HIC)和中低收入国家(LMIC)的年龄和性别特异性周围动脉疾病患病率,并将其与联合国人口数相结合估算全球患病率。对15种周围动脉疾病的假定危险因素实施相关性比值比(OR)荟萃分析,并在8个WHO区域利用危险因素预测周围动脉疾病数。
  
结果显示,共有包括112027例受试者的34项研究符合纳入标准,其中9347例伴有周围动脉疾病。来自于HIC和LMIC的研究分别为22和12项。性别特异性患病率随年龄增加而升高;在男、女性以及HIC和LMIC中均基本相似。在HIC中,45~49岁男性和女性的患病率分别为5.28%和5.41%,85~89岁的男性和女性分别为18.83%和18.38%。LMIC男性的患病率低于HIC男性。在LMIC,女性发病率高于男性,尤其在女性年轻阶段(45—49岁)。
  
在HIC和LMIC,吸烟均为重要危险因素(当前吸烟的OR分别为2.72和1.42),其次为糖尿病高血压和高胆固醇血症。2010年,全球有2.02亿人伴有周围动脉疾病,其中69.7%生活在LMIC。在过去十年间,LMIC和HIC的周围动脉疾病患病人数分别增加28.7%和13.1%。

原文出处:

Fowkes FG, Rudan D, Rudan I, Aboyans V, Denenberg JO, McDermott MM, Norman PE, Sampson UK, Williams LJ, Mensah GA, Criqui MH.Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis.Lancet. 2013 Oct 19;382(9901):1329-40. doi: 10.1016/S0140-6736(13)61249-0.【原文下载】

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1827637, encodeId=432e182e63725, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 16 05:11:00 CST 2014, time=2014-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490447, encodeId=438a149044e78, content=<a href='/topic/show?id=633c39511f9' target=_blank style='color:#2F92EE;'>#周围动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39511, encryptionId=633c39511f9, topicName=周围动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b1c8754678, createdName=xiongliangxl, createdTime=Wed Oct 30 05:11:00 CST 2013, time=2013-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6252, encodeId=9da26252b7, content=lancet好有正义感啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=112.65.244.92, createdTime=Tue Oct 29 13:53:00 CST 2013, time=2013-10-29, status=1, ipAttribution=)]
    2014-04-16 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1827637, encodeId=432e182e63725, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 16 05:11:00 CST 2014, time=2014-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490447, encodeId=438a149044e78, content=<a href='/topic/show?id=633c39511f9' target=_blank style='color:#2F92EE;'>#周围动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39511, encryptionId=633c39511f9, topicName=周围动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b1c8754678, createdName=xiongliangxl, createdTime=Wed Oct 30 05:11:00 CST 2013, time=2013-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6252, encodeId=9da26252b7, content=lancet好有正义感啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=112.65.244.92, createdTime=Tue Oct 29 13:53:00 CST 2013, time=2013-10-29, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1827637, encodeId=432e182e63725, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 16 05:11:00 CST 2014, time=2014-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490447, encodeId=438a149044e78, content=<a href='/topic/show?id=633c39511f9' target=_blank style='color:#2F92EE;'>#周围动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39511, encryptionId=633c39511f9, topicName=周围动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b1c8754678, createdName=xiongliangxl, createdTime=Wed Oct 30 05:11:00 CST 2013, time=2013-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6252, encodeId=9da26252b7, content=lancet好有正义感啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=112.65.244.92, createdTime=Tue Oct 29 13:53:00 CST 2013, time=2013-10-29, status=1, ipAttribution=)]
    2013-10-29 112.65.244.92

    lancet好有正义感啊

    0

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