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Diabetes Care:急性高血糖对1型糖尿病青少年空间工作记忆能力的影响

2020-06-01 MedSci原创 MedSci原创

急性高血糖对T1D青少年的sWM能力会产生负面影响,这与受试者的日常功能和学习成绩有关。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,这项研究旨在调查急性高血糖对1型糖尿病(T1D)青少年脑功能的影响。

20名T1D参与者(年龄为14.64±1.78岁)和20名年龄相匹配的健康对照受试者(年龄为14.40±2.82岁)进行了两次功能性MRI检查。T1D参与者在正常血糖下进行第一次检查,在高血糖钳制下(20 mmol/L[360 mg/dL])进行第二次检查。

研究人员观察到T1D受试者急性高血糖期间空间工作记忆(sWM)能力较低,并且在sWM任务的不同阶段中,感兴趣的脑区激活程度存在显著差异(P=0.014)。

由此可见,急性高血糖对T1D青少年的sWM能力会产生负面影响,这与受试者的日常功能和学习成绩有关。

原始出处:

Jasna Šuput Omladič,et al.Acute Hyperglycemia and Spatial Working Memory in Adolescents With Type 1 Diabetes.Diabetes Care.2020.https://doi.org/10.2337/dc20-0171

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    2020-06-03 hbwxf
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    2020-06-01 misszhang

    谢谢MedSci提供最新的资讯

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在青春期和成年早期被诊断出癌症的幸存者的治疗预后未从在儿童时期被诊断出癌症的幸存者的特征中独立分离出来。本研究拟对早期青少年和青年癌症幸存者的长期健康和全因及特殊原因的死亡率进行评估。儿童癌症调查研究(CCSS)是一个回顾性的队列研究,对1970年至1999年期间美国和加拿大27个学术机构中21岁以前诊断为癌症的5年幸存者进行纵向随访。评估了早期青少年和青年癌症幸存者(15-20岁时确诊)和15岁

BMJ:母亲患有精神疾病对婴儿青少年时期受伤风险的影响

本项研究旨在确定父母心理疾病与后代受伤风险之间的关系。

Hypertension:儿童期或青少年期血压升高与成年时心血管疾病结局

总之,该系统评价和荟萃分析证实,儿童或青少年BP升高与成年时心血管疾病的一些中间指标和直接结局有关。这些发现强调了维持儿童和青少年血压正常的重要性。

Stroke:青少年脑卒中患者局灶性脑动脉病

局灶性脑动脉病是一种年轻人动脉缺血性卒中罕见的病因。随访颅内成像检查对鉴别进展性动脉病变至关重要。

Diabetes Care:青少年肥胖症与早发2型糖尿病

严重肥胖显著增加了成年男性和女性T2D发生的风险。青少年严重肥胖症患病率的上升可能会在未来几十年内增加年轻人的糖尿病发病率。

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