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BMC Cell Biol:英科学家找到神奇分子,衰老细胞重获新生,人类寿命可被延长

2017-11-09 Cell 佚名

【衰老新突破:新分子可以使衰老的细胞重获新生】埃克塞特大学分子遗传学小组发现了一种恢复不活跃衰老细胞的新方法。可以在几个小时之内,使衰老的细胞重新正常分裂。此次研究重点在于研究小分子调制剪接因子表达,从而救援细胞衰老问题,研究结果发表在《BMC细胞生物学》杂志中。

【衰老新突破:新分子可以使衰老的细胞重获新生】埃克塞特大学分子遗传学小组发现了一种恢复不活跃衰老细胞的新方法。可以在几个小时之内,使衰老的细胞重新正常分裂。此次研究重点在于研究小分子调制剪接因子表达,从而救援细胞衰老问题,研究结果发表在《BMC细胞生物学》杂志中。

埃克塞特大学的研究团队发现剪接因子可以重新激活化学物质,使衰老细胞不仅看起来年轻,而且还可以像年轻细胞似的开始分裂。在此次研究中,研究人员应用一种物质叫白藜芦醇的类似物,这种物质一般存在于红酒,黑巧克力,红葡萄和蓝莓中。拼接因素引起化学物质进行切换,把随着年龄逐渐关闭的细胞唤醒,数小时内,细胞看起来年轻了,并且开始进行正常的细胞分裂。

这一发现很可能带来更好的疗法,来帮助人们应对退行性衰老的影响。大多数人都会经历某种慢性疾病,这是随着年龄的增长引起的问题,比如说,老年人更容易中风,患心脏病和癌症。

研究人员表示:“此次研究的目的不仅希望延长人类的寿命,还希望人类可以健康的度过一生。我们的数据表明,使用化学物质来切换的主要类基因,可以让老旧的细胞恢复功能。当我看到培养皿中的细胞重获新生时,我也不敢相信自己的眼睛,因为速度真的是太快了,就像变魔术一样,这些衰老的细胞真的恢复了,因此,我又进行了反复的验证,多次重复实验的过程中,在每种情况下细胞都可以新生。”

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    2018-06-18 维他命
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    2018-10-20 sunylz

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