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Nat Biotechnol:可穿戴汗液传感器问世

2019-12-09 佚名 中国科学报

近日,美国加州理工学院研究人员制备出一款可穿戴汗液传感器,通过修饰电极等方式,实现了酪氨酸等多种汗液中生物标记物的有效探测,为建立全面的健康管理辅助系统提供了新思路。相关研究结果发表于《自然—生物技术》。

近日,美国加州理工学院研究人员制备出一款可穿戴汗液传感器,通过修饰电极等方式,实现了酪氨酸等多种汗液中生物标记物的有效探测,为建立全面的健康管理辅助系统提供了新思路。相关研究结果发表于《自然—生物技术》。

汗液挥发较快且易受到污染,如何有效采集、准确检测汗液是科研人员面临的一大难题。因此,寻找一种实用性强、稳定性高、低成本、简易化的工艺手段是关键。

该论文通讯作者、加州理工学院医学工程系助理教授高伟介绍,汗液的有效采集与及时更新,需要借助微流道结构,而现阶段微流道结构的加工多采用光刻等复杂工艺,成本高、效率低,不利于大规模制备。

经过大量研究,高伟研究团队发现,CO2 激光加工有不同的工作模式,其中矢量模式下诱导产生的石墨烯具有多孔结构,可对外界的应变作出响应,将其作为压阻式传感器能够实现人体呼吸、心跳等生理信号的监测。在尝试不同的激光加工参数后,研究人员完成了微流道结构的设计,研发出灵敏度高、稳定性优异、可对多种物质进行有效探测的电化学传感器。

高伟表示,对于年龄偏大或者运动能力较弱的人群,通过运动出汗可能会导致身体不适,而通过无痛电刺激出汗,并辅助该传感贴片,能够非侵入式地持续对汗液中生物标记物进行检测。

原始出处:

Yang, Y., Song, Y., Bo, X. et al. A laser-engraved wearable sensor for sensitive detection of uric acid and tyrosine in sweat. Nat Biotechnol (2019) doi:10.1038/s41587-019-0321-x.

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    2020-02-13 sunylz
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    2020-04-19 cathymary
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    2020-03-13 shock_melon
  5. [GetPortalCommentsPageByObjectIdResponse(id=1918951, encodeId=59b819189519e, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Thu Feb 13 08:31:00 CST 2020, time=2020-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1925034, encodeId=190d1925034e2, content=<a href='/topic/show?id=732d64313b2' target=_blank style='color:#2F92EE;'>#汗液传感器#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64313, encryptionId=732d64313b2, topicName=汗液传感器)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbf451, createdName=陈吴1234, createdTime=Wed Sep 09 20:31:00 CST 2020, time=2020-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1927725, encodeId=cb67192e725a0, content=<a href='/topic/show?id=a59234e3b4' target=_blank style='color:#2F92EE;'>#Biotech#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3473, encryptionId=a59234e3b4, topicName=Biotech)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Sun Apr 19 16:31:00 CST 2020, time=2020-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1652389, encodeId=4bda1652389cb, content=<a href='/topic/show?id=13d01e24509' target=_blank style='color:#2F92EE;'>#TEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17245, encryptionId=13d01e24509, topicName=TEC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=852f24292001, createdName=shock_melon, createdTime=Fri Mar 13 01:31:00 CST 2020, time=2020-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884042, encodeId=18a31884042b1, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Tue Jan 21 00:31:00 CST 2020, time=2020-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1752715, encodeId=71711e52715c7, content=<a href='/topic/show?id=0b696431277' target=_blank style='color:#2F92EE;'>#汗液#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64312, encryptionId=0b696431277, topicName=汗液)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b8bd36554172, createdName=ewsr13, createdTime=Wed Dec 18 10:31:00 CST 2019, time=2019-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493691, encodeId=f1a114936910c, content=<a href='/topic/show?id=e3a72586595' target=_blank style='color:#2F92EE;'>#传感器#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25865, encryptionId=e3a72586595, topicName=传感器)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=06f59086560, createdName=mjldent, createdTime=Wed Dec 11 09:31:00 CST 2019, time=2019-12-11, status=1, ipAttribution=)]
    2020-01-21 liye789132251
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    2019-12-18 ewsr13
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    2019-12-11 mjldent

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