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中国研究登ASCO更佳!中山大学马骏团队等提出治疗鼻咽癌新方法,能把3年死亡风险降低57%

2019-06-02 普外科曾医生 今日头条

中国研究登ASCO最佳!中山大学马骏团队等提出治疗鼻咽癌新方法,能把3年死亡风险降低57%北京时间6月1日凌晨,举世瞩目的美国临床肿瘤学会(ASCO)2019年会在芝加哥(比北京时间慢13个小时)正式开幕。来自中山大学肿瘤防治中心的马骏教授,在大会上口头报告了由中国医生和科学家主导、研究对象为中国肿瘤患者的临床研究成果。在这项研究成果中,马骏和孙颖教授等开创新地在同期标准放化疗前,增加利用吉西他滨

中国研究登ASCO最佳!中山大学马骏团队等提出治疗鼻咽癌新方法,能把3年死亡风险降低57%

北京时间6月1日凌晨,举世瞩目的美国临床肿瘤学会(ASCO)2019年会在芝加哥(比北京时间慢13个小时)正式开幕。

来自中山大学肿瘤防治中心的马骏教授,在大会上口头报告了由中国医生和科学家主导、研究对象为中国肿瘤患者的临床研究成果。

在这项研究成果中,马骏和孙颖教授等开创新地在同期标准放化疗前,增加利用吉西他滨+顺铂(简称GP)方案诱导化疗治疗局部晚期鼻咽癌。

与标准治疗组相比,增加GP诱导化疗能把患者的3年无瘤生存率从76.5%提高到85.3%,复发或死亡风险降低49%;3年总生存率从90.3%提高到94.6%,死亡风险降低57%。

据悉,这是首次有大型前瞻性Ⅲ期临床试验证实,吉西他滨+顺铂(简称GP)方案诱导化疗治疗局部晚期鼻咽癌有效。

此外,这项重要的研究成果不仅获得ASCO的最佳研究(Best of ASCO)殊荣,还同步刊登在顶级医学期刊《新英格兰医学期刊》(NEJM)上[1]。这也是中国内地学者主导的肿瘤学研究第一次问鼎该杂志,以及第一次在ASCO会议期间同步发表的NEJM论文。

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