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BMJ:研究表明类风湿性关节炎患者房颤和卒中风险高

2012-03-12 MedSci MedSci原创

近日,国际著名杂志《英国医学杂志》British Medical Journal上在线刊登了丹麦的一项全国队列研究,研究结果表明,与一般人群相比,类风湿性关节炎(RA)患者房颤风险增高40%,卒中风险增高30% 。 研究者、丹麦Hellerup市Gentofte医院心内科的研究员Jesper Lindhardsen医生指出,既往研究显示RA与心肌梗死风险增高之间具有相关性,但对卒中风险的研究

近日,国际著名杂志《英国医学杂志》British Medical Journal上在线刊登了丹麦的一项全国队列研究,研究结果表明,与一般人群相比,类风湿性关节炎(RA)患者房颤风险增高40%,卒中风险增高30% 。 研究者、丹麦Hellerup市Gentofte医院心内科的研究员Jesper Lindhardsen医生指出,既往研究显示RA与心肌梗死风险增高之间具有相关性,但对卒中风险的研究数据不一致。为此,他和同事回顾了一项全国性注册研究的数据,这项研究中纳入所有截至1997年1月1日年龄超过15岁的丹麦人,其中18,247人患有RA。 结果显示,在最长达13年的随访期间,共有156,484人被诊断患有房颤,其中包括774例RA患者,共有165,343人发生卒中,其中包括 718例RA患者。RA患者的房颤(卒中的一项可纠正危险因素)发生率为每8.2起事件/1,000(患者·年),而一般人群发生率为6起事件 /1,000(患者·年)。女性的风险略高于男性,并且最低年龄组的风险显著偏高。“RA引起的绝对风险在最高年龄组和最低年龄组分别为25%和70%,其他年龄组介于这两个数字之间”。RA

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    2013-02-18 gaoxiaoe
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    2012-03-14 lmm397
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