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Ann Surg:一般外科手术后,适合多少阿片类药物处方?

2016-09-27 MedSci MedSci原创

目的:调查一般外科手术后,阿片类药物的处方模式,并估计出理想的处方数量。背景:阿片类药物使用过量会导致死亡率的增加,关于一般外科手术后,阿片类药物处方的最佳剂量的数据是缺乏的。方法:我们对来自5个门诊部门的642例患者进行了评估:部分乳房切除术(PM)、部分乳房切除术+前哨淋巴结活检(PM SLNB)、腹腔镜胆囊切除术(LC)、腹腔镜腹股沟疝修补术(LiH)和开放式腹股沟疝修补术(IH)。获取患者

目的:调查一般外科手术后,阿片类药物的处方模式,并估计出理想的处方数量。

背景:阿片类药物使用过量会导致死亡率的增加,关于一般外科手术后,阿片类药物处方的最佳剂量的数据是缺乏的。

方法:我们对来自5个门诊部门的642例患者进行了评估:部分乳房切除术(PM)、部分乳房切除术+前哨淋巴结活检(PM SLNB)、腹腔镜胆囊切除术(LC)、腹腔镜腹股沟疝修补术(LiH)和开放式腹股沟疝修补术(IH)。获取患者术后阿片类药物处方使用情况,并进行了一次电话调查,以确定术后使用阿片类药物的数量。

结果:相同操作者进行的手术后,不同患者使用阿片类药物的数量差异很大。中位阿片类药物处方数量(范围):PM 20 (0-50)、PM SLNB 20 (0-60)、LC 30 (0-100)、LIH 30 (15-70)和IH 30 (15-120)。患者只服用了28%的处方药。不同手术方式后的处方药使用百分比不同: PM 15%、PM SLNB 25%、LC 33%、LIH 15%和IH 31%。不到2%的患者,得到了阿片类药物补充。

我们识别了能满足80%患者的阿片类药物数量:PM 5、PM SLNB 10、LC 15、LIH 15和IH 15。如果将将这些数量进行规定,那么首次开具阿片类药物的处方数量会是实际数量的43%。

结论:一般外科手术后,阿片类药物处方数量变化很大。许多情况下,阿片类药物是过量的。使用我们估计出来的理想阿片类药物处方数,外科医生不仅能合理管理患者的术后疼痛,还能显著降低阿片类药物处方数量。

原始出处:

Hill, Maureen V.et al.Wide Variation and Excessive Dosage of Opioid Prescriptions for Common General Surgical Procedures.Annals of Surgery: September 14, 2016

本文系梅斯医学(MedSci)原创编译整理,转载需授权! 

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    2016-10-12 1e10c84am36(暂无匿称)

    好文章,受益

    0

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    2016-09-29 lhlxtx
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