Baidu
map

J Urol:青春期精索静脉曲张男性的总能动精子数与激素水平和睾丸总体积有关

2020-10-29 AlexYang MedSci原创

患有精索静脉曲张青少年中,关于未来不育的风险因素存在争议,且对激素水平和精液参数之间的关系知之甚少。精液分析(SA)可能是最接近生育能力的标志物,但在一些男孩中可能难以获得,主要是因为一些个人、家庭或

患有精索静脉曲张青少年中,关于未来不育的风险因素存在争议,且对激素水平和精液参数之间的关系知之甚少。精液分析(SA)可能是最接近生育能力的标志物,但在一些男孩中可能难以获得,主要是因为一些个人、家庭或宗教原因。确定异常精液参数的其他临床替代物能够为评估这些男孩的精索静脉曲张严重程度提供选择。最近,有研究人员假设了激素水平和TTV可以预测TMSC的异常。

研究包括了78名男孩(中位年龄17.5岁)。研究发现,LH、AMH和总睾酮与任何SA参数均无相关性。FSH与TMSC之间呈现负相关关系(ρ=-0.35,p=0.004),抑制素B与TMSC之间呈现正相关关系(ρ=0.50,p<0.001)。另外,TTV与TMSC显著正相关(ρ=0.35,p=0.01)。ROC分析显示,预测异常TMSC的最佳FSH截断值为2.9,最佳inhibinB截断值为204,最佳TTV截止值为34.4cc。

与异常TMSC相关的3种风险因素最终优化截断值

最后,研究人员指出,TMSC与FSH水平成反比,与抑制素B水平和TTV直接相关。血清FSH、抑制素B和TTV的优化截断值可以成为因个人或宗教/文化原因推迟SA男孩TMSC的合理代用指标。

原始出处:

Jason P Van Batavia , Elizabeth Lawton , Jennifer R Frazier et al. Total Motile Sperm Count in Adolescent Boys with Varicocele is Associated with Hormone Levels and Total Testicular Volume. J Urol. Oct 2020

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1998332, encodeId=dfba1998332b2, content=<a href='/topic/show?id=499c6683554' target=_blank style='color:#2F92EE;'>#激素水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66835, encryptionId=499c6683554, topicName=激素水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Sat Jan 02 08:35:46 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647464, encodeId=8d53164e46496, content=<a href='/topic/show?id=09aae659182' target=_blank style='color:#2F92EE;'>#精索静脉曲张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76591, encryptionId=09aae659182, topicName=精索静脉曲张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a3c23418627, createdName=minlingfeng, createdTime=Tue Jun 22 21:35:46 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698159, encodeId=f0ad1698159ed, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Tue Apr 06 05:35:46 CST 2021, time=2021-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275549, encodeId=147912e5549ba, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368402, encodeId=e5f113684023f, content=<a href='/topic/show?id=2fa7e3068b9' target=_blank style='color:#2F92EE;'>#睾丸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73068, encryptionId=2fa7e3068b9, topicName=睾丸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1998332, encodeId=dfba1998332b2, content=<a href='/topic/show?id=499c6683554' target=_blank style='color:#2F92EE;'>#激素水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66835, encryptionId=499c6683554, topicName=激素水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Sat Jan 02 08:35:46 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647464, encodeId=8d53164e46496, content=<a href='/topic/show?id=09aae659182' target=_blank style='color:#2F92EE;'>#精索静脉曲张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76591, encryptionId=09aae659182, topicName=精索静脉曲张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a3c23418627, createdName=minlingfeng, createdTime=Tue Jun 22 21:35:46 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698159, encodeId=f0ad1698159ed, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Tue Apr 06 05:35:46 CST 2021, time=2021-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275549, encodeId=147912e5549ba, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368402, encodeId=e5f113684023f, content=<a href='/topic/show?id=2fa7e3068b9' target=_blank style='color:#2F92EE;'>#睾丸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73068, encryptionId=2fa7e3068b9, topicName=睾丸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1998332, encodeId=dfba1998332b2, content=<a href='/topic/show?id=499c6683554' target=_blank style='color:#2F92EE;'>#激素水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66835, encryptionId=499c6683554, topicName=激素水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Sat Jan 02 08:35:46 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647464, encodeId=8d53164e46496, content=<a href='/topic/show?id=09aae659182' target=_blank style='color:#2F92EE;'>#精索静脉曲张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76591, encryptionId=09aae659182, topicName=精索静脉曲张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a3c23418627, createdName=minlingfeng, createdTime=Tue Jun 22 21:35:46 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698159, encodeId=f0ad1698159ed, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Tue Apr 06 05:35:46 CST 2021, time=2021-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275549, encodeId=147912e5549ba, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368402, encodeId=e5f113684023f, content=<a href='/topic/show?id=2fa7e3068b9' target=_blank style='color:#2F92EE;'>#睾丸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73068, encryptionId=2fa7e3068b9, topicName=睾丸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
    2021-04-06 fusion
  4. [GetPortalCommentsPageByObjectIdResponse(id=1998332, encodeId=dfba1998332b2, content=<a href='/topic/show?id=499c6683554' target=_blank style='color:#2F92EE;'>#激素水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66835, encryptionId=499c6683554, topicName=激素水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Sat Jan 02 08:35:46 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647464, encodeId=8d53164e46496, content=<a href='/topic/show?id=09aae659182' target=_blank style='color:#2F92EE;'>#精索静脉曲张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76591, encryptionId=09aae659182, topicName=精索静脉曲张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a3c23418627, createdName=minlingfeng, createdTime=Tue Jun 22 21:35:46 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698159, encodeId=f0ad1698159ed, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Tue Apr 06 05:35:46 CST 2021, time=2021-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275549, encodeId=147912e5549ba, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368402, encodeId=e5f113684023f, content=<a href='/topic/show?id=2fa7e3068b9' target=_blank style='color:#2F92EE;'>#睾丸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73068, encryptionId=2fa7e3068b9, topicName=睾丸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1998332, encodeId=dfba1998332b2, content=<a href='/topic/show?id=499c6683554' target=_blank style='color:#2F92EE;'>#激素水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66835, encryptionId=499c6683554, topicName=激素水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Sat Jan 02 08:35:46 CST 2021, time=2021-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1647464, encodeId=8d53164e46496, content=<a href='/topic/show?id=09aae659182' target=_blank style='color:#2F92EE;'>#精索静脉曲张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76591, encryptionId=09aae659182, topicName=精索静脉曲张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a3c23418627, createdName=minlingfeng, createdTime=Tue Jun 22 21:35:46 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1698159, encodeId=f0ad1698159ed, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Tue Apr 06 05:35:46 CST 2021, time=2021-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275549, encodeId=147912e5549ba, content=<a href='/topic/show?id=5d0299032b9' target=_blank style='color:#2F92EE;'>#青春期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99032, encryptionId=5d0299032b9, topicName=青春期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368402, encodeId=e5f113684023f, content=<a href='/topic/show?id=2fa7e3068b9' target=_blank style='color:#2F92EE;'>#睾丸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73068, encryptionId=2fa7e3068b9, topicName=睾丸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Sat Oct 31 04:35:46 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
    2020-10-31 zhangph

相关资讯

Eur Urol:精索静脉曲张会导致健康男性精液质量降低

研究人员指出,精索静脉曲张会导致健康男性的精液质量降低,并改变男性雄激素水平。欧洲泌尿协会指出,约15%的成年男性会出现精索静脉曲张,导致男性出现原发性不孕(35-44%)或继发性不孕症(45-81%)的风险增加。 丹麦哥本哈根大学的Niels Joergensen博士和同事们对7000多名欧洲青年进行精索静脉曲张、睾丸功能测试、精液和机体雄激素水平分析等数据进行了探究。他们指出,超过六分之一的男

精索静脉曲张4种术式的临床疗效比较

本文转载自《中华男科学杂志》2016,22(4):311-314 原文作者:李虎、文艳玲、董超雄、何祖强、蒋涛、曾繁英、王锋锋 作者单位:广州市白云区第一人民医院泌尿外科、广州中山大学附属第六医院超声科 精索静脉曲张是青年男性最常见的泌尿系统疾病之一,在男性不育症患者的发病率(30%~40%)显著高于一般人群(15%~20%),也是男性不育症中最宜手术矫正的病因。对于症状严重、已经影响到

Sci Rep:精索静脉曲张分级中,调查彩色多普勒超声回流模式作用的新方法

精索静脉曲张是造成不育的最为常见的起因,并且可以修复。彩色多普勒超声(CDUS)对该条件下对精索静脉曲张的诊断结果具有97%的敏感度和94%的特异性。最近,有研究人员提出了一种新的阴囊多普勒模式,来预测精索静脉曲张的严重度。研究在2016年1月到2017年1月进行,且为一项观察性的研究。研究包括了120个测试单元和60名患者。研究人员对所有参与者进行了阴囊CDUS和精液分析,并对回流模式、蔓状静脉

精索静脉曲张手术治疗安全共识

原发性精索静脉曲张(VC)的治疗总体上根据患者静脉曲张程度、有无临床症状、伴或不伴不育或精液质量异常,以及有无其他并发症等情况区别对待。治疗方法包括手术治疗和非手术治疗,多数文献报道以手术治疗为主。手术方法包括传统开放手术、显微外科手术、腹腔镜手术及介入栓塞术等。非手术方法包括药物治疗、阴囊托法、降温疗法、饮食调节、心理干预等。为规范VC的手术治疗,与会专家依据最新的循证医学资料以及临床诊治经验,

阴囊上的“蚯蚓”吃掉生育力

张先生今年32岁,最近总感觉左下腹部和阴囊坠胀不适,摸起来阴囊里面有鼓鼓囊囊的东西,特别是在长时间走路的情况下症状更加严重。张先生从网上了解到这种情况有可能是精索静脉曲张,而且这种病会造成不能生育。虽然张先生婚后已经有了一个活泼可爱的宝宝,但是想要二胎的想法依然使他非常担忧,因此他来到医院就诊。医生给他做了体检和B超检查,明确诊断为精索静脉曲张(中度),而且精液分析结果异常。医生建议张先生采用手术

NEJM:一例肾癌致急性精索静脉曲张的案例报道

男性患者,65岁,因4周前左侧睾丸开始出现肿胀而到泌尿外科门诊就诊,既往没有相关的泌尿外科病史。

Baidu
map
Baidu
map
Baidu
map