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Eur Radiol:那种基础病会加速肺癌的进展,特发性间质性肺炎?慢性阻塞性肺疾病?

2017-11-20 shaosai MedSci原创

本研究旨在评价特发性间质性肺炎(IIP)与慢性阻塞性肺疾病(COPD)患者中利用容积倍增时间(VDT)比较肺癌的进展速度,并将结果发表在Eur Radiol上。

本研究旨在评价特发性间质性肺炎(IIP)与慢性阻塞性肺疾病(COPD)患者中利用容积倍增时间(VDT)比较肺癌的进展速度,并将结果发表在Eur Radiol上。

本研究共纳入了61例患者(IIP32例,COPD29例)。由一名放射科医生手动对肺癌进行三维分割。计算VDTs并在两组中进行比较。利用Logistic回归分析验证与肿瘤快速生长的相关性因子(VDT< 90天)。

在IIP患者中肺癌中位VDT(78.2天)要明显短于COPD的肺癌患者(126.1天; p=0.004)。在IIP患者中鳞状细胞癌(SqCC)是肺癌中最常见的亚型,其次是小细胞肺癌(SCLC)。在COPD患者中,SqCC是最常见的亚型,其次是腺癌。肿瘤快速生长在IIP及COPD中分别为20例、9例(p=0.021)。SCLC与肿瘤快速生长具有显着相关性(p=0.038)。多变量分析表明IIP的基础病是肿瘤快速生长的独立预测因子(p = 0.016;OR, 3.7)。

本研究表明,在IIP中的肺癌生长更快,中位VDT< 90天。因此,在IIP并怀疑肺癌的患者中,当进行CT随访时,随访间期应该更加频繁(<90天)。

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    2018-07-25 tomyang96
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    2017-11-20 天涯183

    非常好的文章.学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1815766, encodeId=8e941815e6691, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Sun Sep 16 20:25:00 CST 2018, time=2018-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1705157, encodeId=b2b21e05157b9, content=<a href='/topic/show?id=d8a66e9084d' target=_blank style='color:#2F92EE;'>#特发性间质性肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67908, encryptionId=d8a66e9084d, topicName=特发性间质性肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d2c630942744, createdName=jmtang, createdTime=Mon Jul 23 10:25:00 CST 2018, time=2018-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1894636, encodeId=2d3c189463686, content=<a href='/topic/show?id=e45b6e859f3' target=_blank style='color:#2F92EE;'>#特发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67859, encryptionId=e45b6e859f3, topicName=特发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Mon Jun 11 09:25:00 CST 2018, time=2018-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696782, encodeId=68f31696e82d4, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Jul 25 07:25:00 CST 2018, time=2018-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262854, encodeId=94e426285457, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Mon Nov 20 14:03:23 CST 2017, time=2017-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262847, encodeId=8d4126284e8b, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Nov 20 13:16:00 CST 2017, time=2017-11-20, status=1, ipAttribution=)]
    2017-11-20 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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