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职业健康丨护士患COPD?或许与消毒剂的使用不无关系!

2017-10-29 刘金淑 赵博 陈志锦 SIFIC感染官微

根据在美国超过5.5万名护士中发现该疾病的新研究,经常使用消毒剂与诱发慢性阻塞性肺疾病(COPD)的较高风险相关。

根据在美国超过5.5万名护士中发现该疾病的新研究,经常使用消毒剂与诱发慢性阻塞性肺疾病(COPD)的较高风险相关。

法国维勒瑞夫岛国家健康与医学研究院的奥里安·杜马斯博士,欲将在欧洲呼吸学会的国际会议上阐述,由于消毒剂中存在的特殊化学物质,某些涉及到经常暴露于消毒剂的工作,如表面清洁消毒,与COPD发生风险增加22%-32%有关。

杜马和她的同事们分析了在1989年开始的美国护士健康研究II登记的55185名注册护士的数据。他们研究那些2009年未患COPD且一直从事护理工作的护士,对她们进行为期8年的追踪研究,直到2017年5月。在此期间,663名护士被诊断患有COPD。护士暴露于消毒剂的评估是通过问卷形式和工作或任务分配所建立的暴露模型进行。结果调整考虑了可能影响评估结果的因素,如吸烟、年龄、体重指数和种族等。

杜马斯说:“我们发现,经常使用消毒剂清洁表面的护士(至少每周使用一次)患COPD的风险增加了22%。但是建议每周使用消毒剂来清洁仪器在统计学上并没有意义。”

研究人员还研究了特定消毒剂的暴露:戊二醛(一种用于医疗器械的高效消毒剂)、漂白剂、过氧化氢、酒精和季铵盐类化合物(亦称为“季铵盐”,主要用于地板和家具等表面的低水平消毒)。所有这些都与患COPD的风险增加24%—32%有关。

杜马斯补充说:“在我们的研究中,37%的护士每周使用消毒剂清洁物表,19%的护士每周使用消毒剂清洁医疗器械。”

以往的研究已经将消毒剂与卫生保健工作者中的哮喘等呼吸问题联系起来。她接着说:“接触消毒剂对COPD的潜在不利影响受到的关注较少,尽管最近在欧洲的两项研究表明,保洁工作者患COPD的风险更高。但据我们所知,我们是首个报道医务工作者患COPD和使用消毒剂之间的联系,同时也对可能导致两者关联性的特定化学成分进行研究。我们的研究结果进一步证明了接触消毒剂对呼吸系统疾病的影响,并强调了将职业健康因素纳入医院等卫生保健机构清洁和消毒指导方案的紧迫性。这些都是初步的发现,还需要进行更多的研究。特别是,我们需要调查终身职业接触化合物对COPD的影响,并阐明每种特定消毒剂的作用。我们希望得到疾病和预防控制中心(CDC)的资助,以继续这项重要工作。其中一些消毒剂,如漂白剂和季铵盐,常用于普通家庭,而家用消毒剂对COPD发展的潜在影响尚不清楚。早期研究发现,哮喘和接触家用清洁产品和消毒剂有关系,例如漂白剂和喷雾剂,因此进一步的研究是非常重要的。”

杜马斯强调,因为这是一项观察性研究,研究结果并不能说明消毒剂引致COPD,只是有些消毒剂和该疾病的发展有关。

原始出处:
European Lung Foundation. Nurses' regular use of disinfectants is associated with developing COPD. Science Daily. September 2017.

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    2018-04-12 871538379

    申报职业病

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    2017-11-01 杏林一叶

    建议研究者开展消毒剂生产人员COPD发病率研究.如果结果阳性.则更有说服力.

    0

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    2017-10-31 yfjms

    学习了

    0

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    2017-10-31 huperzia
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    2017-10-29 天涯183

    非常好的文章.学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=304971, encodeId=ae033049e170, content=申报职业病, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35e76003, createdName=871538379, createdTime=Thu Apr 12 06:02:48 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2058942, encodeId=c1fa2058942ec, content=<a href='/topic/show?id=c4dd805e09d' target=_blank style='color:#2F92EE;'>#职业健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80570, encryptionId=c4dd805e09d, topicName=职业健康)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c64275, createdName=piaojinhua, createdTime=Thu Jan 25 20:38:00 CST 2018, time=2018-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257870, encodeId=9b7c25e8706b, content=建议研究者开展消毒剂生产人员COPD发病率研究.如果结果阳性.则更有说服力., beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dbbe2184942, createdName=杏林一叶, createdTime=Wed Nov 01 20:05:59 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257501, encodeId=8b8525e50165, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Oct 31 12:09:24 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489423, encodeId=1dde148942305, content=<a href='/topic/show?id=a66865e9926' target=_blank style='color:#2F92EE;'>#消毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65799, encryptionId=a66865e9926, topicName=消毒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71d48549435, createdName=huperzia, createdTime=Tue Oct 31 02:38:00 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500043, encodeId=fcc9150004353, content=<a href='/topic/show?id=61876580359' target=_blank style='color:#2F92EE;'>#消毒剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65803, encryptionId=61876580359, topicName=消毒剂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3529418442, createdName=listen321, createdTime=Tue Oct 31 02:38:00 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256983, encodeId=9c0e256983f0, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Oct 29 15:42:45 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256969, encodeId=4331256969ab, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sun Oct 29 13:49:49 CST 2017, time=2017-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=256933, encodeId=c15f25693343, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Oct 29 11:52:23 CST 2017, time=2017-10-29, status=1, ipAttribution=)]
    2017-10-29 戒馋,懒,贪

    谢谢分享.学习了

    0

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    2017-10-29 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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