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JCEM:不孕妇女的睡眠习惯有何特点

2021-07-06 MedSci原创 MedSci原创

伴有PCOS的不孕妇女比UI的妇女更常发生睡眠障碍。胰岛素抵抗与阻塞性睡眠呼吸暂停、习惯性打鼾和睡眠时间短相关。阻塞性睡眠呼吸暂停的临床症状或睡眠时间短并不影响对生育治疗的反应。

睡眠在代谢和生殖功能中发挥着重要的作用,而多囊卵巢综合征(PCOS)与睡眠障碍相关,包括阻塞性睡眠呼吸暂停发生率增加。

近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,研究人员旨在评估多囊卵巢综合征的不孕妇女睡眠参数,并与不明原因的不孕妇女(UI)进行比较,以确定睡眠紊乱的危险因素。

研究人员对来自两个随机临床试验中诊断为PCOS或UI的女性进行了前瞻性队列研究。该研究的参与者为1603名不孕妇女,主要结局指标为自我报告的睡眠指标。

UI和PCOS妇女的睡眠习惯

相比于UI女性,PCOS女性睡眠时间短于6小时(6.1% vs. 2.7%;P<0.001)、习惯性打鼾(37.8% vs. 19.0%;P<0.001)以及嗜睡(12.0% vs. 8.6%;P<0.026)更为常见。校正协变量后,PCOS和空腹胰岛素升高与阻塞性睡眠呼吸暂停(OSA)的临床症状相关(p=0.010),而PCOS、胰岛素升高(p=0.003)、腰围超过88cm(p=0.003)和吸烟(p=0.012)与习惯性打鼾相关。临床抑郁评分(P<0.001)和PCOS诊断(p=0.002)与白天嗜睡相关。睡眠时间短和阻塞性睡眠呼吸暂停的临床症状与妊娠率和活产率无关。

由此可见,伴有PCOS的不孕妇女比UI的妇女更常发生睡眠障碍。胰岛素抵抗与阻塞性睡眠呼吸暂停、习惯性打鼾和睡眠时间短相关。阻塞性睡眠呼吸暂停的临床症状或睡眠时间短并不影响对生育治疗的反应。

原始出处:

Esther Eisenberg.et al.Sleep Habits of Women with Infertility.JCEM.2021.https://doi.org/10.1210/clinem/dgab474

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    2021-08-08 achengzhao
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    2021-11-18 smallant2015
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    2021-07-08 鲜嫩如花的小春

    受益匪浅

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2063458, encodeId=42e5206345851, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sun Aug 08 21:23:23 CST 2021, time=2021-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1949478, encodeId=793619494e802, content=<a href='/topic/show?id=af57e297647' target=_blank style='color:#2F92EE;'>#睡眠习惯#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72976, encryptionId=af57e297647, topicName=睡眠习惯)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sat Nov 13 14:23:23 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1778076, encodeId=eff71e780767f, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Thu Nov 18 21:23:23 CST 2021, time=2021-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997554, encodeId=ee0399e55496, content=受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53281706489, createdName=鲜嫩如花的小春, createdTime=Thu Jul 08 15:24:22 CST 2021, time=2021-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997343, encodeId=ddcb99e343d4, content=PCOS更容易发生睡眠障碍, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210618/d4b39622af1c46d4886da9fdbd48a3c3/c7f1cfe5950c4c3192d875e6c253548b.jpg, createdBy=2de02385971, createdName=maidoumengmeng, createdTime=Wed Jul 07 22:45:16 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997159, encodeId=fdab99e1597a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eca02558264, createdName=125580d4m44暂无昵称, createdTime=Wed Jul 07 13:22:04 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997074, encodeId=9bd099e074cc, content=受益匪浅<a href='/topic/show?id=1c1710265113' target=_blank style='color:#2F92EE;'>#高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102651, encryptionId=1c1710265113, topicName=高血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f1e5543438, createdName=纸老虎, createdTime=Wed Jul 07 11:09:20 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997068, encodeId=252699e0687b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2eb25542885, createdName=ms3000002052890081, createdTime=Wed Jul 07 10:59:34 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996959, encodeId=e08e9969593e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210624/3da0b4e87d244fc8964a8bc9c1f7d3b8/e4798d77bda342298fe093b744b40344.jpg, createdBy=e2623291388, createdName=Avigo, createdTime=Tue Jul 06 23:56:19 CST 2021, time=2021-07-06, status=1, ipAttribution=)]
    2021-07-07 maidoumengmeng

    PCOS更容易发生睡眠障碍

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2063458, encodeId=42e5206345851, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sun Aug 08 21:23:23 CST 2021, time=2021-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1949478, encodeId=793619494e802, content=<a href='/topic/show?id=af57e297647' target=_blank style='color:#2F92EE;'>#睡眠习惯#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72976, encryptionId=af57e297647, topicName=睡眠习惯)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c0050, createdName=lishiwen, createdTime=Sat Nov 13 14:23:23 CST 2021, time=2021-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1778076, encodeId=eff71e780767f, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Thu Nov 18 21:23:23 CST 2021, time=2021-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997554, encodeId=ee0399e55496, content=受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=53281706489, createdName=鲜嫩如花的小春, createdTime=Thu Jul 08 15:24:22 CST 2021, time=2021-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997343, encodeId=ddcb99e343d4, content=PCOS更容易发生睡眠障碍, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210618/d4b39622af1c46d4886da9fdbd48a3c3/c7f1cfe5950c4c3192d875e6c253548b.jpg, createdBy=2de02385971, createdName=maidoumengmeng, createdTime=Wed Jul 07 22:45:16 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997159, encodeId=fdab99e1597a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eca02558264, createdName=125580d4m44暂无昵称, createdTime=Wed Jul 07 13:22:04 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997074, encodeId=9bd099e074cc, content=受益匪浅<a href='/topic/show?id=1c1710265113' target=_blank style='color:#2F92EE;'>#高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102651, encryptionId=1c1710265113, topicName=高血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f1e5543438, createdName=纸老虎, createdTime=Wed Jul 07 11:09:20 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=997068, encodeId=252699e0687b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2eb25542885, createdName=ms3000002052890081, createdTime=Wed Jul 07 10:59:34 CST 2021, time=2021-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=996959, encodeId=e08e9969593e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210624/3da0b4e87d244fc8964a8bc9c1f7d3b8/e4798d77bda342298fe093b744b40344.jpg, createdBy=e2623291388, createdName=Avigo, createdTime=Tue Jul 06 23:56:19 CST 2021, time=2021-07-06, status=1, ipAttribution=)]
    2021-07-07 125580d4m44暂无昵称

    学习了

    0

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    2021-07-07 纸老虎

    受益匪浅#高血压#

    0

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    2021-07-07 ms3000002052890081

    学习

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    2021-07-06 Avigo

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