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INGREZZA治疗迟发性运动障碍的长期有效性

2019-10-03 Allan MedSci原创

Neurocrine生物科技公司近日宣布,每日一次的INGREZZA能够改善迟发性运动障碍(TD)患者的长期症状。

Neurocrine生物科技公司近日宣布,每日一次的INGREZZA能够改善迟发性运动障碍(TD)患者的长期症状。这项临床研究(RE-KINECT试验)是临床医生在TD患者中进行的最大规模研究。这些数据将在2019103日至6日在圣地亚哥举行的2019年年度心理大会上发表。

迟发性运动障碍(Tardive dyskinesia, TD)是长期使用多巴胺受体阻滞剂后迟发发作的一种多动性运动障碍,这些阻滞剂主要是抗精神病药物以及止吐药甲氧氯普胺。TD的临床表现多种多样,包括舞蹈病、手足徐动症、肌张力障碍、静坐不能、刻板行为,罕见情况下还包括震颤。术语迟发性将这些运动障碍与急性运动障碍、帕金森综合征以及静坐不能相鉴别,后三者在使用抗精神病药后很快出现。


原始出处:

http://www.firstwordpharma.com/node/1670894#axzz611EW3gzs

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    2020-01-06 canlab
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    2019-10-03 一天没事干

    很好的学习机会

    0

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2019年帕金森病及相关疾病世界大会(IAPRD):INGREZZA和Opicapone的全新数据

Neurocrine生物医学近日宣布,它将在IAPRD上展示其两项运动障碍实验的数据,以验证INGREZZA(缬氨苄嗪,美国FDA批准用于治疗迟发性运动障碍的首款药物)和opicapone(帕金森病研究性辅助治疗药物)的有效性和安全性。

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