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JAMA Pediatr:母乳喂养对婴儿肠道菌群的影响

2017-05-10 zhangfan MedSci原创

母乳中的细菌犹如是婴儿肠道中的种子,对婴儿肠道菌群构建和发展至关重要,该研究再次强调了母乳喂养的重要性

婴儿时期建立肠道菌群对健康和免疫产生终生的影响。研究发现母乳喂养婴儿的肠道菌群与非母乳喂养婴儿不同,这种差异从婴幼儿期持续至成年后。母乳中含有多种多样的细菌,但是很少有人知道细菌是如何通过母乳喂养由母亲向婴儿垂直转移的。近日研究人员就乳汁和乳晕皮肤与婴儿肠道细菌群落之间的关系进行了研究。

研究在2010年至2015年间进行,研究人员利用16S核糖体RNA基因测序技术确定了母乳,乳晕皮肤和107名健康婴儿的粪便样本的细菌组成并确定每日母乳喂养的数量和持续时间以及固体食物引进的时机对婴儿肠道细菌的影响。

在107对健康的母亲和婴儿中,试验时婴儿平均月龄40天,52名(43.0%)为男婴。研究发现母乳、乳晕皮肤和粪便的细菌群落在组成和多样性方面存在差异。婴儿肠道微生物群落与其母亲的乳汁和皮肤细菌接近,与他人差异较大(平均Bray-Curtis差异系数,0.012生母,0.014他人,P<0.001)。源跟踪分析评估母乳和乳晕皮肤微生物对婴儿肠道菌群的贡献发现,在出生后的前30天,母乳喂养占总摄入量75%以上的婴儿,有平均27.7%的细菌来自母乳,平均10.3%的细菌来自乳晕皮肤。细菌多样性和组成变化与每日母乳摄入量的比例呈剂量依赖性,即使在引入固体食物之后也是如此。

研究表明,母乳中的细菌犹如是婴儿肠道中的种子,对婴儿肠道菌群构建和发展至关重要,该研究再次强调了母乳喂养的重要性。

原始出处:


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    2017-08-08 feather89
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    2017-05-31 I come

    母乳喂养重要

    0

  5. 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encodeId=1b661962e84f, content=学习了,可是没办法不得不放弃母乳喂养, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Wed May 10 15:42:33 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196234, encodeId=69f519623400, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 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    2017-05-20 I come

    学习了,谢谢分享

    0

  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Fri May 12 05:04:00 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392247, encodeId=802a139224e0b, content=<a href='/topic/show?id=223081e33b6' target=_blank style='color:#2F92EE;'>#肠道菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81733, encryptionId=223081e33b6, topicName=肠道菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa292500107, createdName=1249897bm37(暂无昵称), createdTime=Fri May 12 05:04:00 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196278, encodeId=1b661962e84f, content=学习了,可是没办法不得不放弃母乳喂养, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Wed May 10 15:42:33 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196234, encodeId=69f519623400, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 10 14:14:46 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-12 villahu
  7. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf1b289, createdName=villahu, createdTime=Fri May 12 05:04:00 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392247, encodeId=802a139224e0b, content=<a href='/topic/show?id=223081e33b6' target=_blank style='color:#2F92EE;'>#肠道菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81733, encryptionId=223081e33b6, topicName=肠道菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa292500107, createdName=1249897bm37(暂无昵称), createdTime=Fri May 12 05:04:00 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196278, 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10 14:14:46 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1637730, encodeId=4321163e73057, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Tue Dec 12 15:04:00 CST 2017, time=2017-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665013, encodeId=eadd1665013bb, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, 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    2017-05-10 1dd8aa01m06(暂无匿称)

    学习了,可是没办法不得不放弃母乳喂养

    0

  9. 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encodeId=1b661962e84f, content=学习了,可是没办法不得不放弃母乳喂养, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Wed May 10 15:42:33 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196234, encodeId=69f519623400, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 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    2017-05-10 三生有幸9135

    学习一下谢谢分享

    0

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