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JBJS:戒烟可减轻腰背痛患者的疼痛

2012-12-11 JBJS: JBJS:

       许多研究表明吸烟与腰痛、腰椎间盘突出症、患者术后预后不良的风险增加具有关。骨与关节外科杂志(JBJS)2012年12月发表的一项最新研究还发现,患脊柱疾病和相关腰背部疼痛的吸烟者,与在8个月治疗期停止吸烟的脊柱疾病患者相比,不适感更为显著。        几乎所有的成年人都可能在某段时间内因背部疼痛或其

       许多研究表明吸烟与腰痛、腰椎间盘突出症、患者术后预后不良的风险增加具有关。骨与关节外科杂志(JBJS)2012年12月发表的一项最新研究还发现,患脊柱疾病和相关腰背部疼痛的吸烟者,与在8个月治疗期停止吸烟的脊柱疾病患者相比,不适感更为显著。


       
几乎所有的成年人都可能在某段时间内因背部疼痛或其他疼痛性脊柱疾患而就诊。吸烟已被确定为慢性疼痛性疾病一个可改变的危险因素,因此研究人员回顾了8个月内5300多例接受手术或非手术治疗的腰背部或腿部神经根性疼痛的脊柱疾病患者的吸烟史并监测患者自我报告的疼痛情况。

       在进入研究时,从未吸烟者和已戒烟患者疼痛明显比目前吸烟者和在研究期间戒烟的患者更轻。当前吸烟患者在(VAS)疼痛评分报告最差,当前和平均每周疼痛评分均显示,目前吸烟者较从未吸烟者疼痛更严重。

       其他主要调查结果:
       治疗过程中戒烟的患者与继续吸烟者相比,背部疼痛改善更显著。
       非吸烟者VAS疼痛评分平均改善具有临床显著性。
       治疗过程中继续吸烟患者报告的疼痛无临床显著性改善。
       从未吸烟者与目前吸烟者相比,Oswestry功能障碍指数(腰背疼痛评估最常用的测量指标)的平均改善更显著。

       “我们知道,尼古丁可使疼痛加剧,该项研究发现,如果在治疗过程中戒烟,预后更好;如果继续吸烟,无论接受何种治疗均不能显著改善疼痛症状。如果吸烟,则手术或非手术改善症状的可能性会显著下降。”罗切斯特大学骨科Glenn R. Rechtine博士说。“这项研究发现疼痛性脊柱疾病患者的疼痛改善与戒烟之间存在强相关,腰背痛患者有必要戒烟。” 




Background: 
Smoking is associated with low back pain, intervertebral disc disease, inferior patient outcomes following surgical interventions, and increased rates of postoperative complications. The purpose of the present study was to examine the effect of smoking and smoking cessation on pain and disability in patients with painful spinal disorders.
Methods: 
We examined a prospectively maintained database of records for 5333 patients with axial or radicular pain from a spinal disorder with regard to smoking history and the patient assessment of pain on four visual analog scales during the course of care. Confounding factors, including secondary gain, sex, age, and body mass index, were also examined. The mean duration of follow-up was eight months. Multivariate statistical analysis was performed with variables including smoking status, secondary gain status, sex, depression, and age as predictors of pain and disability.
Results: 
Compared with patients who had never smoked, patients who were current smokers reported significantly greater pain in all visual analog scale pain ratings (p < 0.001). The mean improvement in reported pain over the course of care was significantly different between nonsmokers and current smokers (p <0.001). Compared with patients who had continued to smoke, those who had quit smoking during the course of care reported significantly greater improvement in pain in visual analog scale pain ratings for worst (p = 0.013), current (p < 0.05), and average weekly pain (p = 0.024). The mean improvement in the visual analog scale pain ratings was clinically important in patients in all three groups of nonsmokers. As a group, those who had continued smoking during treatment had no clinically important improvement in reported pain.
Conclusions: 
Given a strong association between improved patient-reported pain and smoking cessation, this study supports the need for smoking cessation programs for patients with a painful spinal disorder.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=5214, encodeId=ad505214d1, content=好文章,是不是以后门诊也可以这么建议腰背痛患者, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4ebe74199, createdName=zcf0806, createdTime=Sun Dec 16 19:20:00 CST 2012, time=2012-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1342016, encodeId=6f41134201621, content=<a href='/topic/show?id=c0b8835e6c5' target=_blank style='color:#2F92EE;'>#背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83576, encryptionId=c0b8835e6c5, topicName=背痛)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/xkicoVBAnV4HxvdCqC1viaW8wdLQdN9hVP9icgqqDsxC6UVPjfhogdfc2iaU1xNUMVlFl5QicicWrjWQBTsVye5ngOQQ/132, createdBy=f92f2500185, createdName=ms7405317358118777, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424941, encodeId=75af14249417a, content=<a href='/topic/show?id=798c8548e1c' target=_blank style='color:#2F92EE;'>#腰背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85487, encryptionId=798c8548e1c, topicName=腰背痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a0f3933653, createdName=feather79, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598820, encodeId=a4a6159882061, content=<a href='/topic/show?id=0b8e102617c' target=_blank style='color:#2F92EE;'>#JBJS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10261, encryptionId=0b8e102617c, topicName=JBJS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef5818636905, createdName=qingrejiedu, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=)]
    2012-12-16 zcf0806

    好文章,是不是以后门诊也可以这么建议腰背痛患者

    0

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  3. [GetPortalCommentsPageByObjectIdResponse(id=5214, encodeId=ad505214d1, content=好文章,是不是以后门诊也可以这么建议腰背痛患者, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4ebe74199, createdName=zcf0806, createdTime=Sun Dec 16 19:20:00 CST 2012, time=2012-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1342016, encodeId=6f41134201621, content=<a href='/topic/show?id=c0b8835e6c5' target=_blank style='color:#2F92EE;'>#背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83576, encryptionId=c0b8835e6c5, topicName=背痛)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/xkicoVBAnV4HxvdCqC1viaW8wdLQdN9hVP9icgqqDsxC6UVPjfhogdfc2iaU1xNUMVlFl5QicicWrjWQBTsVye5ngOQQ/132, createdBy=f92f2500185, createdName=ms7405317358118777, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424941, encodeId=75af14249417a, content=<a href='/topic/show?id=798c8548e1c' target=_blank style='color:#2F92EE;'>#腰背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85487, encryptionId=798c8548e1c, topicName=腰背痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a0f3933653, createdName=feather79, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598820, encodeId=a4a6159882061, content=<a href='/topic/show?id=0b8e102617c' target=_blank style='color:#2F92EE;'>#JBJS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10261, encryptionId=0b8e102617c, topicName=JBJS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef5818636905, createdName=qingrejiedu, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=5214, encodeId=ad505214d1, content=好文章,是不是以后门诊也可以这么建议腰背痛患者, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4ebe74199, createdName=zcf0806, createdTime=Sun Dec 16 19:20:00 CST 2012, time=2012-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1342016, encodeId=6f41134201621, content=<a href='/topic/show?id=c0b8835e6c5' target=_blank style='color:#2F92EE;'>#背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83576, encryptionId=c0b8835e6c5, topicName=背痛)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/xkicoVBAnV4HxvdCqC1viaW8wdLQdN9hVP9icgqqDsxC6UVPjfhogdfc2iaU1xNUMVlFl5QicicWrjWQBTsVye5ngOQQ/132, createdBy=f92f2500185, createdName=ms7405317358118777, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424941, encodeId=75af14249417a, content=<a href='/topic/show?id=798c8548e1c' target=_blank style='color:#2F92EE;'>#腰背痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85487, encryptionId=798c8548e1c, topicName=腰背痛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a0f3933653, createdName=feather79, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598820, encodeId=a4a6159882061, content=<a href='/topic/show?id=0b8e102617c' target=_blank style='color:#2F92EE;'>#JBJS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10261, encryptionId=0b8e102617c, topicName=JBJS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef5818636905, createdName=qingrejiedu, createdTime=Wed Dec 12 15:00:00 CST 2012, time=2012-12-12, status=1, ipAttribution=)]
    2012-12-12 qingrejiedu

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病例讨论: 腰背痛、全身皮肤进行性变硬

来源:中国医学论坛报 上海交通大学医学院附属仁济医院 丁慧华   ■ 病史简介   患者男,58岁,主因“腰背痛伴全身皮肤变硬8年”入院。8年前,患者无明显诱因出现腰背部疼痛,在当地医院行磁共振成像(MRI)检查提示腰椎间盘突出,对症治疗后可缓解。后逐渐出现双手指间、指蹼皮肤发白变硬,伴皮肤紧绷感;双侧肘膝关节屈侧及小腿皮肤变硬紧绷,尚未影响肢体运动;无面部皮疹,关节肿胀、强直,雷诺现象

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