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Immunotherapy:舌下免疫治疗对屋尘螨诱导的过敏性鼻炎和并发症的疗效分析

2019-10-22 AlexYang MedSci原创

最近,有研究人员调查了舌下免疫治疗对尘螨诱导的过敏性鼻炎和其过敏性并发症的影响。研究是一个前瞻性的案例对照研究,包括了120名患者(案例80,对照40),调查持续的时间为12个月。研究发现,舌下免疫治疗能够在尘螨诱导的过敏性鼻炎中减少53.65%的总鼻炎症状(p<0.0001),但在对照中不存在上述情况(-7.3%, p=0.99)。总症状评分中的并发哮喘评分从17.79减少到了8.8(p&

最近,有研究人员调查了舌下免疫治疗对尘螨诱导的过敏性鼻炎和其过敏性并发症的影响。

研究是一个前瞻性的案例对照研究,包括了120名患者(案例80,对照40),调查持续的时间为12个月。研究发现,舌下免疫治疗能够在尘螨诱导的过敏性鼻炎中减少53.65%的总鼻炎症状(p<0.0001),但在对照中不存在上述情况(-7.3%, p=0.99)。总症状评分中的并发哮喘评分从17.79减少到了8.8(p<0.0001);而过敏性结膜炎从20.89减少到了10.0(p=0.0002);过敏性皮肤炎从46.40减少到了29.38(p=0.0004),并且其中74.6%的患者停止使用鼻腔类固醇药物。另外,治疗有关的副作用反应均是轻微的且是自我可控的。

最后,研究人员指出,尽管舌下免疫治疗要比传统的治疗方法更贵,但是作为一种辅助治疗能够不仅仅改善过敏性鼻炎结果,而且可以改善预期共存的并发症。

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    2020-08-05 丁鹏鹏
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    2019-10-23 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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    2019-10-23 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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2019年欧洲肿瘤内科学会(ESMO)年会于西班牙巴塞罗那举行,该会议是欧洲最负盛名和最具影响力的肿瘤学会议,会议期间有大量肿瘤临床治疗相关的研究结果公布,为推动肿瘤诊疗发挥巨大作用。在本次ESMO大会上,肿瘤免疫治疗(IO)仍是会议的热点内容。在消化道肿瘤领域,特别是食管癌的治疗方面,今年的重磅研究当属ATTRACTION-3研究,这是首个证实无论PD-L1是否表达阳性,PD-1单抗对比化疗二线

PACIFIC研究影响NSCLC免疫治疗临床实践,获益或不止步于Ⅲ期患者

Ⅲ期非小细胞肺癌(NSCLC)患者数量庞大,占所有NSCLC患者人数的1/3左右,其诊断相对复杂,治疗方式也多种多样。Ⅲ期不可手术NSCLC的5年生存率为约20%左右,其标准治疗为以铂类药物为基础的同步放化疗,然而在相当长一段时间内,大多数患者的临床结局未得到改善。PACIFIC研究的成功,打破了治疗的困局。广东省人民医院的乔贵宾教授对Ⅲ期NSCLC诊疗现状和免疫治疗临床实践等热点问题进行解读。

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