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Nature Communications:瑞德西韦联合疗法可治疗晚期马尔堡病毒病

2021-03-27 Allan MedSci原创

德克萨斯大学加尔维斯顿分校的加尔维斯顿国家实验室(UTMB)进行的一项新研究表明,单克隆抗体联合抗病毒药物瑞德西韦治疗晚期马尔堡病毒感染症具有巨大益处。

马尔堡病毒引致的疾病起病很急,伴有严重头痛和严重不适。许多患者在5至7天内出现严重出血。致命病例通常出现某种形式的出血,经常是多个部位出血。而1998年-2000年在刚果民主共和国和2005年在安哥拉暴发的疫情中病死率高达80%以上。

德克萨斯大学加尔维斯顿分校的加尔维斯顿国家实验室(UTMB)进行的一项新研究表明,单克隆抗体联合抗病毒药物瑞德西韦治疗晚期马尔堡病毒感染症具有巨大益处。该研究今天发表在《Nature Communications》之上。

UTMB的微生物学和免疫学系教授,这项研究的主要研究者Geisbert表示:“与引起埃博拉病毒的病毒一样,马尔堡病毒也属于高致病性病毒。我们的数据表明,瑞德西韦联合疗法有助于晚期患者的康复”。

UTMB团队和Gilead公司一直在开发单克隆抗体(mAb)治疗方法,以治疗像马尔堡病毒和埃博拉病毒这样的极其危险的病毒感染。事实证明,这些疗法在实验室研究和紧急使用中非常有效。

 

原始出处:

https://www.firstwordpharma.com/node/1813512?tsid=4

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    2022-02-21 liye789132251
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    2021-06-18 liuli5079
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    2021-03-28 1436749007

    我学到了很多东西谢谢老师

    0

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