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Diabetic Med:儿童时期移民到以色列与青少年时期的糖尿病有关

2017-11-30 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于对270万青少年的研究,研究发现儿童时期移民到以色列与青少年时期的糖尿病有关。移民研究可以揭示糖尿病的发病机制和风险因素。为此,研究人员调查了移民以色列年龄与青少年糖尿病发病之间的关系。

近日,国际杂志 《Diabetic Med》上在线发表一项关于对270万青少年的研究,研究发现儿童时期移民到以色列与青少年时期的糖尿病有关。移民研究可以揭示糖尿病的发病机制和风险因素。为此,研究人员调查了移民以色列年龄与青少年糖尿病发病之间的关系。

研究人员分析了1967年至2014年间义务服兵役的犹太17岁青少年的横断面数据。研究人口包括来自埃塞俄比亚,前苏联,中东,北非(ME / NA)和西方国家的430 176名移民。计算男性和女性糖尿病的OR值,根据移民年龄分组,以以色列出生的参与者作为对照。未经校正和完全校正的模型是为了解释可能的混杂因素。此外,研究人群按来源地分层,每个移民小组都参考同一来源地的以色列出生的参与者。

在全面校正的模型中,各研究组的糖尿病OR值均呈下降趋势。年龄0-5岁的移民与以色列出生的对照组的糖尿病具有可比性;年龄在6-11岁之间移民的OR值为0.8295CI 0.70,0.97; P=0.017),12-19岁的移民最低OR0.6595CI0.54,0.77 ; p <0.0001)。当移民年龄被视为连续变量时,糖尿病发生校正风险为0.9795CI 0.96,0.99; p=0.001)每年递增。在未校正的模型中最近移民中糖尿病的风险较低,并且当研究样本按性别和来源分层时,除了来自ME/NA的移民外,风险持续存在。值得注意的是,在以色列出生的埃塞俄比亚人比5岁以后到达以色列的埃塞俄比亚移民的糖尿病患病率高6倍。

不同种族儿童早期到达的移民相对于在以色列出生的儿童,在青春期失去了不患糖尿病的保护。这可能是由于环境和生活方式的改变,特别是那些从小就开始的改变。

原始出处:

Alon Peled, Barak Gordon, Gilad Twig,et al. Immigration to Israel during childhood is associated with diabetes at adolescence: a study of 2.7 million adolescents

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    2017-12-03 虈亣靌

    学习了谢谢作者分享!

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=1970555, encodeId=82f519e055593, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Tue Dec 19 12:36:00 CST 2017, time=2017-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638229, encodeId=85be163822991, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Mon Sep 03 10:36:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760374, encodeId=5e6f1e603742b, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sun Oct 07 14:36:00 CST 2018, time=2018-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981366, encodeId=5b4c19813663f, content=<a href='/topic/show?id=f78e28313c1' target=_blank style='color:#2F92EE;'>#儿童时期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28313, encryptionId=f78e28313c1, topicName=儿童时期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Sat Apr 28 12:36:00 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266465, encodeId=0b9426646530, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Dec 03 13:10:40 CST 2017, time=2017-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608307, encodeId=125e160830e9c, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Dec 02 13:36:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266150, encodeId=c39026615044, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Dec 02 09:48:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265797, encodeId=0cc4265e97c0, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Dec 01 00:06:44 CST 2017, time=2017-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265789, encodeId=1c46265e89be, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Nov 30 23:10:11 CST 2017, time=2017-11-30, status=1, ipAttribution=)]
    2017-12-02 半夏微凉

    学习了谢谢分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1970555, encodeId=82f519e055593, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Tue Dec 19 12:36:00 CST 2017, time=2017-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638229, encodeId=85be163822991, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Mon Sep 03 10:36:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760374, encodeId=5e6f1e603742b, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sun Oct 07 14:36:00 CST 2018, time=2018-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981366, encodeId=5b4c19813663f, content=<a href='/topic/show?id=f78e28313c1' target=_blank style='color:#2F92EE;'>#儿童时期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28313, encryptionId=f78e28313c1, topicName=儿童时期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Sat Apr 28 12:36:00 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266465, encodeId=0b9426646530, content=学习了谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sun Dec 03 13:10:40 CST 2017, time=2017-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608307, encodeId=125e160830e9c, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Dec 02 13:36:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=266150, encodeId=c39026615044, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Dec 02 09:48:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265797, encodeId=0cc4265e97c0, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Dec 01 00:06:44 CST 2017, time=2017-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=265789, encodeId=1c46265e89be, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Nov 30 23:10:11 CST 2017, time=2017-11-30, status=1, ipAttribution=)]
    2017-12-01 1209e435m98(暂无昵称)

    学习了.谢谢分享!

    0

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    2017-11-30 清风拂面

    学习了.谢谢分享

    0

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