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给人造器官供血

2017-07-06 MedSci MedSci原创

Jelena Rnjak-Kovacina和她的团队在美国新南威尔士大学和美国塔夫斯大学,使用蚕丝来培育血管。这项工作使我们在寻找生物工程组织作为供体器官和组织的可行替代品方面的研究更进一步。生物工程师可以在实验室中建立许多组织,如皮肤、骨骼和肌肉,但最大的障碍是缺乏血液供应。在人体中,厚层组织中的细胞依赖于一个广泛的血管网络,它将氧气和营养物质输送到体内的每个细胞,并带走有害的废物。在没有血管的



Jelena Rnjak-Kovacina和她的团队在美国新南威尔士大学和美国塔夫斯大学,使用蚕丝来培育血管

这项工作使我们在寻找生物工程组织作为供体器官和组织的可行替代品方面的研究更进一步。

生物工程师可以在实验室中建立许多组织,如皮肤、骨骼和肌肉,但最大的障碍是缺乏血液供应。

在人体中,厚层组织中的细胞依赖于一个广泛的血管网络,它将氧气和营养物质输送到体内的每个细胞,并带走有害的废物。

在没有血管的人造组织中,氧气和营养物质只能到达大约半毫米的组织。因此,只有少量的、薄的人造组织才能成功构建。我们当然也就不能构建像肝脏和心脏这样的人造器官。

为了解决这一问题,Jelena设计出了蚕丝支架,它模仿天然血管的特征,促进血管生长。她发现,在蚕丝支架上的中空通道可以促进这一过程。

"到目前为止,这是非常令人鼓舞的,"Jelena说。"这些通道可以在细胞被植入体内之前改善氧气和营养物质的传递,同时也为原生血管的生长提供了空间。"
Giving blood to artificial organs

"如果这些新的结构可以植入到人造身体部位,它们不仅可以构造出更大、更厚的人造结构,而且还可以形成更复杂的形状--甚至人造器官。

这项工作受专利保护,并已发表在专业期刊上。

原文出处https://medicalxpress.com/news/2017-07-blood-artificial.html

此文系梅斯医学(MedSci)原创整理编译,转载须授权!

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    2017-07-07 李东泽

    很好,不错,以后会多学习

    0

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    2017-07-07 qingfengqishi5

    学习了,学习了

    0

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    2017-07-07 杨利洪

    学习了,提高了

    0

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    2017-07-07 1771ae4158m

    学习一下很不错

    0

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    2017-07-07 飛歌

    厉害了我的哥

    0

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    2017-07-06 清风拂面

    谢谢分享,学习了

    0

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    2017-07-06 有备才能无患

    如果这些新的结构可以植入到人造身体部位,它们不仅可以构造出更大、更厚的人造结构,而且还可以形成更复杂的形状--甚至人造器官。

    0

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    2017-07-06 1e14ffd0m25(暂无匿称)

    学习的

    0

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