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Clinica Chimica Acta:孕妇妊娠晚期d -二聚体水平与分娩结局的关系?

2020-03-19 MedSci原创 MedSci原创

本研究目的是探讨中国人群妊娠晚期d -二聚体水平与分娩结局的关系。

本研究目的是探讨中国人群妊娠晚期d -二聚体水平与分娩结局的关系。

研究人员对11570名在同一中心医院分娩的孕妇进行回顾性观察性队列研究。分别从实验室信息系统和医院记录中提取和分析孕妇入院时和妊娠结局时的血浆d -二聚体水平。

研究结果显示,孕妇血浆D-二聚体水平与D-二聚体的最高四分位数(Q)和最低四分位数(Q)的最高胎儿生长指标相关(平均出生体重:145.79 g,平均出生长度:0.11 cm,平均胎龄:0.30周)。 D-二聚体四分位数的增加与较小胎龄(SGA),低出生体重(LBW)和早产(PTB)新生儿的风险降低以及与较大胎龄(LGA)的风险相关,且巨型胎儿(SGA:OR = 0.52,95%CI:0.43,0.64; LBW:OR = 0.58,95%CI:0.38,0.86; PTB:OR = 0.44,95%CI:0.35,0.55; LGA:OR = 2.37 ,95%CI:2.01,2.78;巨型胎儿:OR = 2.59,95%CI,2.06,3.24;Q4与Q1对比)。

研究结果表明,妊娠晚期孕妇血浆d -二聚体水平与分娩结局相关,对这些结局具有风险评估价值。

原始出处:

Xiaosong Yuan,Yanfang Gao,Association of maternal D-dimer level in late pregnancy with birth outcomes in a Chinese cohort

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    2020-12-12 hxj0117
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    2020-07-27 windight
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    2020-03-21 linlin2312
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