FRBM：练肌肉？你可能需要补充点维生素E

2015-05-26 佚名生物谷

众所周知，维生素E是一种强力抗氧化剂，除此之外，科学家们在最近一项研究中发现，如果没有维生素E，细胞质膜就不能正常愈合，而细胞质膜对于保持细胞完整，控制细胞内外物质进出交流具有非常重要的意义。身体内每个细胞都有细胞质膜，并且每个细胞的细胞质膜都有可能发生破损。科学家们认为了解清楚维生素E在细胞膜损伤修复过程中的重要作用，将会对肌肉萎缩，糖尿病相关的肌无力以及创伤性脑损伤的治

众所周知，维生素E是一种强力抗氧化剂，除此之外，科学家们在最近一项研究中发现，如果没有维生素E，细胞质膜就不能正常愈合，而细胞质膜对于保持细胞完整，控制细胞内外物质进出交流具有非常重要的意义。

身体内每个细胞都有细胞质膜，并且每个细胞的细胞质膜都有可能发生破损。科学家们认为了解清楚维生素E在细胞膜损伤修复过程中的重要作用，将会对肌肉萎缩，糖尿病相关的肌无力以及创伤性脑损伤的治疗提供重要启示。

在该项研究中，研究人员分别给予大鼠正常饮食、去除维生素E的饮食以及去除维生素E后再补充维生素E的饮食。他们将大鼠放在跑步机上进行跑步运动确保大鼠具有正常的肌肉离心收缩能力，这种运动能够帮助拉长肌肉，同时也会因为肌肉的收缩和拉长产生疼痛。

经过一段时间观察，研究人员发现饮食中缺少维生素E的大鼠其跑步能力发生下降，尽管它们停下的时候会受到微弱的电刺激，但与对照组大鼠相比，饮食缺少维生素E的大鼠仍会更多次地停留在跑步机底部的格子里。研究人员还利用一种正常情况下不能渗透进入细胞膜的染料进行了实验研究，结果发现这种染料能够轻易透过缺少维生素E的大鼠的肌肉细胞膜。随后，研究人员又在显微镜下观察了运动后不同饮食大鼠的四头肌肌肉纤维，结果发现饮食中有维生素E的大鼠肌肉纤维很快就恢复正常，而缺乏维生素E的大鼠其大腿中最大的肌肉纤维更加细小并且呈现红肿状态，这表明维生素E的缺乏导致大鼠肌肉发生损伤，并且不能进行正常修复过程。

研究人员认为，由于维生素E是脂溶性分子，其能够插入到细胞膜中防止自由基攻击细胞膜，同时还能使磷脂排列一致，加速细胞膜损伤后的修复过程，进而保持肌肉健康。

近日，这项研究成果发表在国际学术期刊Free Radical Biology and Medicine上。

原始出处：

Mohamed Labazi, Anna K. McNeil, Timothy Kurtz, Taylor C. Lee, Ronald B. Pegg, José Pedro Friedmann Angeli, Marcus Conrad, Paul L. McNeil. The antioxidant requirement for plasma membrane repair in skeletal muscle. Free Radical Biology and Medicine, 2015; 84: 246 DOI: 10.1016/j.freeradbiomed.2015.03.016

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2016-02-19 lishizhe

#练肌肉#

107 0
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2015-06-09 ljjj1053

认真学习了

145 0
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2015-05-31 huaxipanxing

看看

188 0
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2015-05-28 marongnuan

#维生素E#

106 0
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2015-05-27 ktorresjie

还是动物实验研究结果，关注下

202 0
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2015-05-27 jasonuclear

好东西

172 0
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2015-05-26 summer474cn

好东西

187 0
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2015-05-26 Dr.LV

好东西

146 0
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2015-05-26 zhoujianyong8416

太好了

122 0

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FRBM：练肌肉？你可能需要补充点维生素E

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