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JCO:左肺癌4L淋巴结清扫的临床意义

2018-08-28 MedSci MedSci原创

JCO近期发表了一篇文章,研究左肺癌4L淋巴结清扫对预后的影响以及4L淋巴结转移的相关危险因素。

JCO近期发表了一篇文章,研究左肺癌4L淋巴结清扫对预后的影响以及4L淋巴结转移的相关危险因素。

作者收集了2005年至2009年间原发左肺癌且接受手术切除的657例患者数据。其中139例患者进行了4L淋巴结清扫(4L D+组),另外518例患者未接受4L淋巴结清扫(4L D-组)。研究终点为无进展生存和总生存情况。研究结果表明,4L站淋巴结转移率为20.9%,显着高于7站(14%)和9站(9.8%)。单因素分析中4L站淋巴结转移与其它站淋巴结转移相关,但在logistic分析中只有10站淋巴结转移是4L站淋巴结转移的独立危险因素。4L站淋巴结清扫组患者生存显着优于未清扫组。调整了潜在混杂因素后,4L淋巴结清扫依然是无病生存和总生存独立有利因素。

文章最后认为,左肺癌4L站淋巴结转移并不少见,4L淋巴结清扫与患者预后改善有关。

原始出处:
Ya-Nan Wang,Shuang Yao,et al.Clinical Significance of 4L Lymph Node Dissection in Left Lung Cancer.JCO.August 2018 doi:10.1200/JCO.2018.78.7101

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    2019-01-03 lidong40
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    2018-08-30 sodoo
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    2018-08-30 amyloid
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    2018-08-29 183****7028

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