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Lancet Diabetes Endo:热量摄入限制与心脏代谢风险研究

2019-07-13 MedSci MedSci原创

中度热量限制显著降低中青年非肥胖人群的多种心脏代谢危险因素

近日研究人员比较了健康、瘦或稍微超重的年轻和中年人中,热量限制和充足营养对心血管代谢危险因素的短期和长期影响。

CALERIE研究在美国开展,21-50岁,BMI22-27.9对的健康非肥胖人群参与,接受25%的限制卡路里饮食或随意对照饮食。评估了25%热量限制饮食对两年内心血管代谢危险因素的影响,包括收缩压、舒张压和平均血压、血脂、高敏感性C-反应蛋白、代谢综合征评分、空腹胰岛素、葡萄糖、胰岛素抵抗和2-h葡萄糖、葡萄糖曲线下面积和口服糖耐量试验。

238名受试者中,218名被随机分配到25%热量限制饮食(n=143,66%)或随意饮食(n=75,34%)。卡路里限制组的个体卡路里摄入量平均减少11.9%,对照组为0.8%;限制组体重减轻7.5千克,对照组为0.1千克,其中71%为脂肪质量减少。热量限制导致传统心脏代谢危险因素2年内显著下降,包括低密度脂蛋白胆固醇、总胆固醇与高密度脂蛋白胆固醇比值、收缩压和心脏舒张压。此外,与对照组相比,热量限制导致2年时C反应蛋白、胰岛素敏感性指数和代谢综合征评分显著改善。

研究认为,中度热量限制显著降低中青年非肥胖人群的多种心脏代谢危险因素。

原始出处:


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    2020-03-05 jyzxjiangqin

    热量摄入量的影响。

    0

  3. 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    2019-09-19 howi
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    2019-08-19 jyzxjiangqin

    心脏代谢风险研究进展。

    0

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  8. 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    2019-08-05 jyzxjiangqin

    热量摄入限制。

    0

  9. 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Circulation:评估心血管风险不必检测“坏胆固醇”,只需要查总胆固醇和“好胆固醇”!

近日,Circulation在线发表的一项针对英国生物样本库的最新数据分析提示,在用血脂指标对无已知心血管病的人群进行心血管风险评估时,仅检测非空腹状态下的总胆固醇和高密度脂蛋白胆固醇(HDL-C,俗称“好胆固醇”)就行,低密度脂蛋白胆固醇(LDL-C,俗称“坏胆固醇”)和近年来比较热门的载脂蛋白(ApoB、ApoA1)水平并无额外的预测价值。

JAMA Inter Med:抽血验血脂,早餐到底吃不吃?

又一项研究指出,对于大多数患者来说,胆固醇测试前没必要禁食。

普通人每天可放心吃一个鸡蛋,胆固醇代谢有问题的人也没事

关于鸡蛋或膳食胆固醇与心血管病之间的关系,近期多项研究结果并不一致。

美专家称:有氧运动降低“坏胆固醇”,运动强度决定“好胆固醇”

在近日召开的美国国家脂质协会(NLA)科学会议上,来自美国康涅狄格大学的血脂专家BethA.Taylor指出,根据近期发布的美国运动指南和心血管病预防指南,医疗人员要着重建议血脂异常患者加强运动,以降低“坏胆固醇”——低密度脂蛋白胆固醇水平。

JAHA:大豆蛋白能够通过降低胆固醇起到心脏保护作用

大豆蛋白食品作为一种有用的植物蛋白食品,具有温和的降胆固醇作用,

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