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Sci Rep：Bio-Gide膜与钛网结合可有效修复种植体周围牙槽骨缺损

2018-11-18 MedSci MedSci原创

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为了指导选择屏障膜治疗种植体周围牙槽骨缺损，我们评估了钛（Ti）网或Bio-Gide膜，单独或组合引导骨再生（GBR）以修复Beagle犬的牙槽骨缺损的效果。拔除三个小猎兔犬的下颌臼齿和第一臼齿后六个月，植入种植体，并分别覆盖有下列膜：A组：种植体+ BIO-Oss + Ti基网，B组：种植体+BIO-Oss + Bio-Gide和C组：植入物+ Bio-Oss + Ti-mesh + Bio-G

为了指导选择屏障膜治疗种植体周围牙槽骨缺损，我们评估了钛（Ti）网或Bio-Gide膜，单独或组合引导骨再生（GBR）以修复Beagle犬的牙槽骨缺损的效果。

拔除三个小猎兔犬的下颌臼齿和第一臼齿后六个月，植入种植体，并分别覆盖有下列膜：A组：种植体+ BIO-Oss + Ti基网，B组：种植体+BIO-Oss + Bio-Gide和C组：植入物+ Bio-Oss + Ti-mesh + Bio-Gide。

在6个月时，micro-CT显示C组的骨量/总体积（BV / TV），小梁数（Tb.N）和小梁厚度（Tb.Th）明显高于其他两组，而小梁分离（Tb.Sp）显著降低，表明骨再生得到改善。C组中三种荧光追踪染料的条带之间的距离明显更大，表明新骨的沉积更快。Bio-Oss颗粒与新沉积的骨骼完美结合，C组骨厚度明显增大。

综上所述，这些研究结果表明，与单独使用钛网或Bio-Gide相比，Bio-Gide膜与钛网结合可有效修复种植体周围牙槽骨缺损，实现骨再生增强，为临床种植手术提供了一种新的治疗理念。

原始出处：

HuiPing Li, JiSi Zheng, et al., Experiment of GBR for repair of peri-implant alveolar defects in beagle dogs. Sci Rep. 2018; 8: 16532.


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    2018-12-19 huangdf

    #种植#

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    2019-08-31 sunylz

    #Bio#

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    2019-06-17 30397613

    #钛#

    0

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    2019-03-28 mei540

    #牙槽骨#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1702011, encodeId=fdc51e020117e, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Wed Dec 19 09:14:00 CST 2018, time=2018-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918401, encodeId=dc6719184015d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat Aug 31 23:14:00 CST 2019, time=2019-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679732, encodeId=058516e9732f6, content=<a href='/topic/show?id=d4ac9639efa' target=_blank style='color:#2F92EE;'>#钛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96397, encryptionId=d4ac9639efa, topicName=钛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=927227807332, createdName=30397613, createdTime=Mon Jun 17 09:14:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1667903, encodeId=c7e0166e903c9, content=<a href='/topic/show?id=64596e594d8' target=_blank style='color:#2F92EE;'>#牙槽骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67594, encryptionId=64596e594d8, topicName=牙槽骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87b426195956, createdName=mei540, createdTime=Thu Mar 28 03:14:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998828, encodeId=9b80199882877, content=<a href='/topic/show?id=26276e60301' target=_blank style='color:#2F92EE;'>#牙槽骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67603, encryptionId=26276e60301, topicName=牙槽骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Sat Jul 06 23:14:00 CST 2019, time=2019-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343846, encodeId=3fb913438464a, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74785, encryptionId=d512e47853f, topicName=种植体)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Tue Nov 20 06:14:00 CST 2018, time=2018-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419280, encodeId=451c1419280ac, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Tue Nov 20 06:14:00 CST 2018, time=2018-11-20, status=1, ipAttribution=)]
    2019-07-06 Smile2680

    #牙槽骨缺损#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1702011, encodeId=fdc51e020117e, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Wed Dec 19 09:14:00 CST 2018, time=2018-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918401, encodeId=dc6719184015d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat Aug 31 23:14:00 CST 2019, time=2019-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679732, encodeId=058516e9732f6, content=<a href='/topic/show?id=d4ac9639efa' target=_blank style='color:#2F92EE;'>#钛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96397, encryptionId=d4ac9639efa, topicName=钛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=927227807332, createdName=30397613, createdTime=Mon Jun 17 09:14:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1667903, encodeId=c7e0166e903c9, content=<a href='/topic/show?id=64596e594d8' target=_blank style='color:#2F92EE;'>#牙槽骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67594, encryptionId=64596e594d8, topicName=牙槽骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87b426195956, createdName=mei540, createdTime=Thu Mar 28 03:14:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998828, encodeId=9b80199882877, content=<a href='/topic/show?id=26276e60301' target=_blank style='color:#2F92EE;'>#牙槽骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67603, encryptionId=26276e60301, topicName=牙槽骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Sat Jul 06 23:14:00 CST 2019, time=2019-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343846, encodeId=3fb913438464a, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74785, encryptionId=d512e47853f, topicName=种植体)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Tue Nov 20 06:14:00 CST 2018, time=2018-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419280, encodeId=451c1419280ac, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Tue Nov 20 06:14:00 CST 2018, time=2018-11-20, status=1, ipAttribution=)]
    2018-11-20 ms6279672939590805

    #种植体#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1702011, encodeId=fdc51e020117e, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Wed Dec 19 09:14:00 CST 2018, time=2018-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918401, encodeId=dc6719184015d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat Aug 31 23:14:00 CST 2019, time=2019-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1679732, encodeId=058516e9732f6, content=<a href='/topic/show?id=d4ac9639efa' target=_blank style='color:#2F92EE;'>#钛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96397, encryptionId=d4ac9639efa, topicName=钛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=927227807332, createdName=30397613, createdTime=Mon Jun 17 09:14:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1667903, encodeId=c7e0166e903c9, content=<a href='/topic/show?id=64596e594d8' target=_blank style='color:#2F92EE;'>#牙槽骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67594, encryptionId=64596e594d8, topicName=牙槽骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87b426195956, createdName=mei540, createdTime=Thu Mar 28 03:14:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998828, encodeId=9b80199882877, content=<a href='/topic/show?id=26276e60301' target=_blank style='color:#2F92EE;'>#牙槽骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67603, encryptionId=26276e60301, topicName=牙槽骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Sat Jul 06 23:14:00 CST 2019, time=2019-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343846, encodeId=3fb913438464a, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74785, encryptionId=d512e47853f, topicName=种植体)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Tue Nov 20 06:14:00 CST 2018, time=2018-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419280, encodeId=451c1419280ac, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Tue Nov 20 06:14:00 CST 2018, time=2018-11-20, status=1, ipAttribution=)]
    2018-11-20 lfcmxl

    #骨缺损#

    0

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