Baidu
map

AIM:柏林倡议研究(BIS)方程可能较肾小球滤过率(GFR)评估老年人肾功更**

2013-07-27 张眉 中国医学论坛报

  ■速读   目前,用于评估肾小球滤过率(GFR)的方程并未在老年人群中经过验证且可能导致慢性肾脏病(CKD)分期被错误评估。为此,有学者就针对老年人群GFR评估的新方程进行了开发,并与原有方程进行了比较。   近日,德国学者的研究表明,对于年龄≥70岁且肾功能正常或轻至中度下降的老年人,在评估其GFR时,该研究团队所开发出的柏林倡议研究(BIS)2方程(见上图)的误差最小。若胱

血友病患儿能运动吗?

  ■速读

  目前,用于评估肾小球滤过率(GFR)的方程并未在老年人群中经过验证且可能导致慢性肾脏病(CKD)分期被错误评估。为此,有学者就针对老年人群GFR评估的新方程进行了开发,并与原有方程进行了比较。

  近日,德国学者的研究表明,对于年龄≥70岁且肾功能正常或轻至中度下降的老年人,在评估其GFR时,该研究团队所开发出的柏林倡议研究(BIS)2方程(见上图)的误差最小。若胱抑素C(Cystatin C)的数据缺乏,则BIS1方程可作为替代评估方法。论文发表于《内科学年鉴》[Ann Intern Med 2012,157(7):471]杂志。    

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1690699, encodeId=8bdc16906992b, content=<a href='/topic/show?id=8ac33486ac' target=_blank style='color:#2F92EE;'>#BIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3486, encryptionId=8ac33486ac, topicName=BIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b53a29082458, createdName=neurowu, createdTime=Thu Aug 15 23:47:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808867, encodeId=bc76180886e71, content=<a href='/topic/show?id=9d788252695' target=_blank style='color:#2F92EE;'>#肾小球滤过#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82526, encryptionId=9d788252695, topicName=肾小球滤过)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ffd5416, createdName=bettycmoon, createdTime=Sat Apr 05 17:47:00 CST 2014, time=2014-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440266, encodeId=be86144026662, content=<a href='/topic/show?id=659b8252ebb' target=_blank style='color:#2F92EE;'>#肾小球滤过率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82527, encryptionId=659b8252ebb, topicName=肾小球滤过率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a744719690, createdName=1249897bm38(暂无昵称), createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534214, encodeId=7f8e1534214d4, content=<a href='/topic/show?id=22b3e9887e' target=_blank style='color:#2F92EE;'>#GFR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7988, encryptionId=22b3e9887e, topicName=GFR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0a812532020, createdName=liuyiping, createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=)]
    2013-08-15 neurowu
  2. [GetPortalCommentsPageByObjectIdResponse(id=1690699, encodeId=8bdc16906992b, content=<a href='/topic/show?id=8ac33486ac' target=_blank style='color:#2F92EE;'>#BIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3486, encryptionId=8ac33486ac, topicName=BIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b53a29082458, createdName=neurowu, createdTime=Thu Aug 15 23:47:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808867, encodeId=bc76180886e71, content=<a href='/topic/show?id=9d788252695' target=_blank style='color:#2F92EE;'>#肾小球滤过#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82526, encryptionId=9d788252695, topicName=肾小球滤过)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ffd5416, createdName=bettycmoon, createdTime=Sat Apr 05 17:47:00 CST 2014, time=2014-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440266, encodeId=be86144026662, content=<a href='/topic/show?id=659b8252ebb' target=_blank style='color:#2F92EE;'>#肾小球滤过率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82527, encryptionId=659b8252ebb, topicName=肾小球滤过率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a744719690, createdName=1249897bm38(暂无昵称), createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534214, encodeId=7f8e1534214d4, content=<a href='/topic/show?id=22b3e9887e' target=_blank style='color:#2F92EE;'>#GFR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7988, encryptionId=22b3e9887e, topicName=GFR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0a812532020, createdName=liuyiping, createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1690699, encodeId=8bdc16906992b, content=<a href='/topic/show?id=8ac33486ac' target=_blank style='color:#2F92EE;'>#BIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3486, encryptionId=8ac33486ac, topicName=BIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b53a29082458, createdName=neurowu, createdTime=Thu Aug 15 23:47:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808867, encodeId=bc76180886e71, content=<a href='/topic/show?id=9d788252695' target=_blank style='color:#2F92EE;'>#肾小球滤过#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82526, encryptionId=9d788252695, topicName=肾小球滤过)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ffd5416, createdName=bettycmoon, createdTime=Sat Apr 05 17:47:00 CST 2014, time=2014-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440266, encodeId=be86144026662, content=<a href='/topic/show?id=659b8252ebb' target=_blank style='color:#2F92EE;'>#肾小球滤过率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82527, encryptionId=659b8252ebb, topicName=肾小球滤过率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a744719690, createdName=1249897bm38(暂无昵称), createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534214, encodeId=7f8e1534214d4, content=<a href='/topic/show?id=22b3e9887e' target=_blank style='color:#2F92EE;'>#GFR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7988, encryptionId=22b3e9887e, topicName=GFR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0a812532020, createdName=liuyiping, createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1690699, encodeId=8bdc16906992b, content=<a href='/topic/show?id=8ac33486ac' target=_blank style='color:#2F92EE;'>#BIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3486, encryptionId=8ac33486ac, topicName=BIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b53a29082458, createdName=neurowu, createdTime=Thu Aug 15 23:47:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808867, encodeId=bc76180886e71, content=<a href='/topic/show?id=9d788252695' target=_blank style='color:#2F92EE;'>#肾小球滤过#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82526, encryptionId=9d788252695, topicName=肾小球滤过)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ffd5416, createdName=bettycmoon, createdTime=Sat Apr 05 17:47:00 CST 2014, time=2014-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440266, encodeId=be86144026662, content=<a href='/topic/show?id=659b8252ebb' target=_blank style='color:#2F92EE;'>#肾小球滤过率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82527, encryptionId=659b8252ebb, topicName=肾小球滤过率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a744719690, createdName=1249897bm38(暂无昵称), createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534214, encodeId=7f8e1534214d4, content=<a href='/topic/show?id=22b3e9887e' target=_blank style='color:#2F92EE;'>#GFR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7988, encryptionId=22b3e9887e, topicName=GFR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0a812532020, createdName=liuyiping, createdTime=Mon Jul 29 01:47:00 CST 2013, time=2013-07-29, status=1, ipAttribution=)]
    2013-07-29 liuyiping

相关资讯

Ann Oncol:老年肺癌患者术后化疗不影响生存质量

  韩国学者的一项研究显示,老年非小细胞肺癌(NSCLC)患者可能存在其它共存病,以及身体机能下降,术后的辅助化疗对老年病人的健康相关生存质量(HRQOL)无显著影响,且治疗前后的HRQOL无显著差别。   该研究于2008年10月到2011年10月期间纳入65岁以上(N=66)和65以下(N=73)的NSCLC患者,比较其化疗后的HRQOL。   结果显示,术后的辅助化疗对老年病人的健康相关

JCE:导管消融较药物治疗对老年性持续性房颤具有更好的疗效

心房颤动是临床上常见的心律失常,它是患者致死、致残及住院的独立预测因素。统计资料表明房颤的发病率随年龄的增加而增加,年龄小于70岁的发病率为1.2%-2.8%,年龄大于80岁的发病率为7.3%-13.7%,房颤的平均发病年龄为75岁,70%的房颤患者年龄大于65岁。转复窦性心律和华法林的使用是改善房颤生存率的两个独立预测因素,然而对于老年患者口服抗凝药物存在较大的风险,首先老年人对华法林较为敏感,

Circulation:老年患者生物瓣和机械瓣置换治疗的长期安全性和有效性

图注:机械瓣和生物瓣患者死亡率(危险因素校正后),主动脉瓣膜置入初,生物瓣治疗患者较机械瓣膜患者再手术风险高。尽管两组总体死亡率相似,超过9年的生物瓣患者相对死亡风险高于机械瓣患者。AV表示主动脉瓣;AVRR表示主动脉瓣修复或置换;Bio代表生物瓣;Mech代表机械瓣。 近年来越来越多老年人接受主动脉瓣置换术治疗,由于机械瓣的血栓风险,生物瓣膜是一个替代选择方案。当前在老年患者中比较生物瓣和机械

Aging Cell:研究发现糖尿病与​​老年痴呆症发病相关

越来越多的证据表明,糖尿病和阿尔茨海默氏病有可能存在某种联系,但糖尿病影响大脑功能和认知的生理机制尚不完全清楚。在一项新的发表在Aging Cell杂志上研究中,索尔克生物研究所研究人员研究表明,糖尿病会加快老化发展,依据阿尔茨海默氏症早在的病理事件。 具体而言,索尔克研究小组发现阿尔茨海默病两个标志,β淀粉样蛋白和tau蛋白存在于糖尿病小鼠大脑中,尤其是在血管周围的细胞中。β淀粉样蛋白的积累被

老年患者围手术期的评估与管理,结合案例分析

典型病例 患者男性,82岁,上楼时跌倒后出现左髋部疼痛,次日发现左腿活动不便。4天后收入北京协和医院骨科。 既往史 慢性胃炎40年,常有反酸症状;持续房颤10余年、未抗凝治疗。否认高血压、冠心病、糖尿病。吸烟40年,2包/天,已戒烟20年。平时未服用特殊药物。 入院诊断 左侧股骨颈骨折。 入院后第3天老年医学组应邀会诊。 查体 体

老年男性残胃癌1例报道及多学科分析

  病例简介   病史及既往史   男性,77岁,因“进食哽噎感1个月”于2010年9月就诊。 既往史: 36年前因良性胃穿孔行远端胃切除毕罗氏I式吻合。   入院检查及诊断   辅助检查   实验室检查异常结果:血红蛋白96 g/L(120~160 g/L),肿瘤标志物糖类抗原(CA19-9)138.9 U/ml。   内

Baidu
map
Baidu
map
Baidu
map