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NEJM:鼻孢子虫病-病例报道

2019-04-04 xing.T 网络

鼻孢子虫病是一种慢性肉芽肿性疾病,由水生的抗原寄生虫西伯鼻孢子菌引起。典型的表现是红色的、易碎的粘膜息肉,通常涉及鼻腔,在触摸时大量出血。口咽,结膜,直肠和外生殖器也可能受到影响。这种疾病在印度和斯里兰卡流行,尽管这种感染也发生在世界其他地区,包括非洲和南美洲。

患者为一名27岁的男性,因进展性梗阻和右鼻孔出血3个月而到耳鼻咽喉科门诊就诊。

体格检查显示红色、颗粒状、带蒂、非脉动性肿块阻塞右鼻腔,并在触摸时出血(如图A所示)。患者报告经常在当地池塘洗澡。切除肿块,并将病灶的基底部进行烧灼。组织病理学检查显示在不同成熟阶段的多个厚壁孢子囊,被致密的炎症(如图B所示,苏木精和伊红染色)包围。诊断为鼻孢子虫病。



鼻孢子虫病是一种慢性肉芽肿性疾病,由水生的抗原寄生虫西伯鼻孢子菌引起。典型的表现是红色的、易碎的粘膜息肉,通常涉及鼻腔,在触摸时大量出血。口咽,结膜,直肠和外生殖器也可能受到影响。这种疾病在印度和斯里兰卡流行,尽管这种感染也发生在世界其他地区,包括非洲和南美洲。

该患者在8个月后的随访中,鼻咽部复发区域被切除。

原始出处:


Chirom A. Singh,et al.Rhinosporidiosis.N Engl J Med 2019;https://www.nejm.org/doi/full/10.1056/NEJMicm1811820

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  1. [GetPortalCommentsPageByObjectIdResponse(id=364781, encodeId=f890364e81da, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqYPFHuMA3bhYQrHvycmum7IJoCsLK0FP6X56Eoj9PZAECDke8zLCKxZZvk9q7B6rZmPuFgN5YCfw/132, createdBy=00912551888, createdName=12543c13m83暂无昵称, createdTime=Wed Apr 17 08:57:38 CST 2019, time=2019-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364145, encodeId=8e09364145c1, content=哎, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Fri Apr 05 08:32:42 CST 2019, time=2019-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034777, encodeId=84ba1034e7749, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Apr 04 11:09:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
    2019-04-17 12543c13m83暂无昵称

    谢谢分享

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  2. [GetPortalCommentsPageByObjectIdResponse(id=364781, encodeId=f890364e81da, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqYPFHuMA3bhYQrHvycmum7IJoCsLK0FP6X56Eoj9PZAECDke8zLCKxZZvk9q7B6rZmPuFgN5YCfw/132, createdBy=00912551888, createdName=12543c13m83暂无昵称, createdTime=Wed Apr 17 08:57:38 CST 2019, time=2019-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364145, encodeId=8e09364145c1, content=哎, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Fri Apr 05 08:32:42 CST 2019, time=2019-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034777, encodeId=84ba1034e7749, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Apr 04 11:09:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
    2019-04-05 smartxiuxiu

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  3. [GetPortalCommentsPageByObjectIdResponse(id=364781, encodeId=f890364e81da, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqYPFHuMA3bhYQrHvycmum7IJoCsLK0FP6X56Eoj9PZAECDke8zLCKxZZvk9q7B6rZmPuFgN5YCfw/132, createdBy=00912551888, createdName=12543c13m83暂无昵称, createdTime=Wed Apr 17 08:57:38 CST 2019, time=2019-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=364145, encodeId=8e09364145c1, content=哎, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Fri Apr 05 08:32:42 CST 2019, time=2019-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034777, encodeId=84ba1034e7749, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Apr 04 11:09:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
    2019-04-04 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

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