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2010年中国慢性淋巴细胞白血病诊断与治疗专家共识

2013-11-22 MedSci MedSci原创

近十几年来,国际上在慢性淋巴细胞白血病(CLL)基础研究、新的预后标志、诊断标准及治疗选择方面都取得了巨大进展,我国对CLL的研究也取得较大进展,但与国外研究差距较大,需要进一步规范临床诊断与治疗,促使我们制订中国CLL诊断与治疗专家共识,以促进我国各级血液科医生提高CLL及相关慢性B淋巴细胞增殖性疾病(B—LPD)的诊断和鉴别诊断水平,规范CLL的治疗。CLL是一种B淋巴细胞克隆性增殖的肿瘤性疾

近十几年来,国际上在慢性淋巴细胞白血病(CLL)基础研究、新的预后标志、诊断标准及治疗选择方面都取得了巨大进展,我国对CLL的研究也取得较大进展,但与国外研究差距较大,需要进一步规范临床诊断与治疗,促使我们制订中国CLL诊断与治疗专家共识,以促进我国各级血液科医生提高CLL及相关慢性B淋巴细胞增殖性疾病(B—LPD)的诊断和鉴别诊断水平,规范CLL的治疗。


CLL是一种B淋巴细胞克隆性增殖的肿瘤性疾病,其特点为成熟形态的淋巴细胞在体内积聚,使血液和骨髓中淋巴细胞增多,进而引起淋巴结、肝、脾肿大,并可累及其他组织器官。CLL特指B细胞肿瘤,既往T—CLL现称为T幼稚淋巴细胞白血病(T-PLL)小细胞变异型。CLL的精确诊断主要依据血细胞计数、血涂片细胞形态学和免疫分型,不典型的患者需要结合其他检查进一步明确。

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