Baidu
map

Arch Osteoporos:脊柱旁肌肉的脂肪浸润与腰椎骨质密度有关

2020-10-01 MedSci原创 MedSci原创

本研究旨在探讨腰椎旁肌肉脂肪浸润与腰椎骨质密度(BMD)的关系,研究结果已在线发表于Arch Osteoporos。

本研究旨在探讨腰椎旁肌肉脂肪浸润与腰椎骨质密度(BMD)的关系,研究结果已在线发表于Arch Osteoporos。

研究共纳入88名受试者(52名女性,36名男性;年龄,46.6±14.2岁;BMI,23.2±3.49kg/m2)。使用基于化学位移编码的水脂MRI,在L2/3、L3/4和L4/5水平测量脊柱旁肌肉(竖脊肌、多指肌和腰肌)的质子密度脂肪分数(PDFF)。使用定量计算机断层扫描(QCT)评估L1、L2和L3的BMD。使用单因素方差分析检验骨密度正常、骨质疏松和骨质疏松症受试者之间的脊柱旁肌PDFF的差异。采用线性回归与年龄、性别、BMI变量分析了耻骨旁肌PDFF与QCT-BMD的关系。

 

结果显示,骨密度正常的受试者的竖脊肌、多头肌、腰肌的PDFF均显著低于骨质减少和骨质疏松症患者(均P<0.001)。校正了年龄、性别、BMI后,脊柱旁肌PDFF与骨密度呈负相关(标准化β系数,- 0.21~- 0.29;均P < 0.05)。

 

综上所述,该研究结果表明,校正年龄、性别和BMI后,椎旁肌脂肪浸润增加,而腰椎BMD降低。脊柱旁肌肉和椎体是相互作用的组织。脊柱旁肌肉脂肪浸润可能是低腰椎BMD的标志。化学移位成像是一种高效、快速的定量方法,当患者在进行常规腰椎MRI检查时,伴有腰背痛时,可以很容易地将其加入临床方案,以测量腰椎旁肌肉PDFF。

 

原始出处:

 

Yinxia ZhaoMingqian Huang, et al., Fatty infiltration of paraspinal muscles is associated with bone mineral density of the lumbar spine. Arch Osteoporos. 2019 Oct 15;14(1):99. doi: 10.1007/s11657-019-0639-5.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1810264, encodeId=1879181026471, content=<a href='/topic/show?id=bdfe8436088' target=_blank style='color:#2F92EE;'>#脂肪浸润#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84360, encryptionId=bdfe8436088, topicName=脂肪浸润)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfa576, createdName=wfang545, createdTime=Sun Dec 20 13:46:44 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1810562, encodeId=7515181056200, content=<a href='/topic/show?id=7e4d854e267' target=_blank style='color:#2F92EE;'>#腰椎骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85472, encryptionId=7e4d854e267, topicName=腰椎骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3e9205, createdName=tidiq, createdTime=Thu Feb 25 10:46:44 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272148, encodeId=a97012e21481f, content=<a href='/topic/show?id=cd1a854340b' target=_blank style='color:#2F92EE;'>#腰椎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85434, encryptionId=cd1a854340b, topicName=腰椎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364659, encodeId=412e13646590d, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1592642, encodeId=4373159264299, content=<a href='/topic/show?id=6dc2101853ed' target=_blank style='color:#2F92EE;'>#骨质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101853, encryptionId=6dc2101853ed, topicName=骨质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1d018108513, createdName=Eleven17, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1810264, encodeId=1879181026471, content=<a href='/topic/show?id=bdfe8436088' target=_blank style='color:#2F92EE;'>#脂肪浸润#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84360, encryptionId=bdfe8436088, topicName=脂肪浸润)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfa576, createdName=wfang545, createdTime=Sun Dec 20 13:46:44 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1810562, encodeId=7515181056200, content=<a href='/topic/show?id=7e4d854e267' target=_blank style='color:#2F92EE;'>#腰椎骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85472, encryptionId=7e4d854e267, topicName=腰椎骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3e9205, createdName=tidiq, createdTime=Thu Feb 25 10:46:44 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272148, encodeId=a97012e21481f, content=<a href='/topic/show?id=cd1a854340b' target=_blank style='color:#2F92EE;'>#腰椎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85434, encryptionId=cd1a854340b, topicName=腰椎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364659, encodeId=412e13646590d, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1592642, encodeId=4373159264299, content=<a href='/topic/show?id=6dc2101853ed' target=_blank style='color:#2F92EE;'>#骨质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101853, encryptionId=6dc2101853ed, topicName=骨质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1d018108513, createdName=Eleven17, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2021-02-25 tidiq
  3. [GetPortalCommentsPageByObjectIdResponse(id=1810264, encodeId=1879181026471, content=<a href='/topic/show?id=bdfe8436088' target=_blank style='color:#2F92EE;'>#脂肪浸润#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84360, encryptionId=bdfe8436088, topicName=脂肪浸润)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfa576, createdName=wfang545, createdTime=Sun Dec 20 13:46:44 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1810562, encodeId=7515181056200, content=<a href='/topic/show?id=7e4d854e267' target=_blank style='color:#2F92EE;'>#腰椎骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85472, encryptionId=7e4d854e267, topicName=腰椎骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3e9205, createdName=tidiq, createdTime=Thu Feb 25 10:46:44 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272148, encodeId=a97012e21481f, content=<a href='/topic/show?id=cd1a854340b' target=_blank style='color:#2F92EE;'>#腰椎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85434, encryptionId=cd1a854340b, topicName=腰椎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364659, encodeId=412e13646590d, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1592642, encodeId=4373159264299, content=<a href='/topic/show?id=6dc2101853ed' target=_blank style='color:#2F92EE;'>#骨质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101853, encryptionId=6dc2101853ed, topicName=骨质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1d018108513, createdName=Eleven17, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1810264, encodeId=1879181026471, content=<a href='/topic/show?id=bdfe8436088' target=_blank style='color:#2F92EE;'>#脂肪浸润#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84360, encryptionId=bdfe8436088, topicName=脂肪浸润)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfa576, createdName=wfang545, createdTime=Sun Dec 20 13:46:44 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1810562, encodeId=7515181056200, content=<a href='/topic/show?id=7e4d854e267' target=_blank style='color:#2F92EE;'>#腰椎骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85472, encryptionId=7e4d854e267, topicName=腰椎骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3e9205, createdName=tidiq, createdTime=Thu Feb 25 10:46:44 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272148, encodeId=a97012e21481f, content=<a href='/topic/show?id=cd1a854340b' target=_blank style='color:#2F92EE;'>#腰椎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85434, encryptionId=cd1a854340b, topicName=腰椎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364659, encodeId=412e13646590d, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1592642, encodeId=4373159264299, content=<a href='/topic/show?id=6dc2101853ed' target=_blank style='color:#2F92EE;'>#骨质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101853, encryptionId=6dc2101853ed, topicName=骨质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1d018108513, createdName=Eleven17, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2020-10-03 lsndxfj
  5. [GetPortalCommentsPageByObjectIdResponse(id=1810264, encodeId=1879181026471, content=<a href='/topic/show?id=bdfe8436088' target=_blank style='color:#2F92EE;'>#脂肪浸润#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84360, encryptionId=bdfe8436088, topicName=脂肪浸润)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cfa576, createdName=wfang545, createdTime=Sun Dec 20 13:46:44 CST 2020, time=2020-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1810562, encodeId=7515181056200, content=<a href='/topic/show?id=7e4d854e267' target=_blank style='color:#2F92EE;'>#腰椎骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85472, encryptionId=7e4d854e267, topicName=腰椎骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3e9205, createdName=tidiq, createdTime=Thu Feb 25 10:46:44 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1272148, encodeId=a97012e21481f, content=<a href='/topic/show?id=cd1a854340b' target=_blank style='color:#2F92EE;'>#腰椎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85434, encryptionId=cd1a854340b, topicName=腰椎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364659, encodeId=412e13646590d, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1592642, encodeId=4373159264299, content=<a href='/topic/show?id=6dc2101853ed' target=_blank style='color:#2F92EE;'>#骨质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101853, encryptionId=6dc2101853ed, topicName=骨质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1d018108513, createdName=Eleven17, createdTime=Sat Oct 03 12:46:44 CST 2020, time=2020-10-03, status=1, ipAttribution=)]
    2020-10-03 Eleven17

相关资讯

JCEM:口服双膦酸盐可减少骨密度异常患者的心血管事件

口服BP用户的CV事件风险降低了33%。这项观察性现实世界研究为口服BP进行心脏保护提供了越来越多的证据,因此有必要在随机试验中进行进一步评估。

糖尿病易致骨质疏松,这7类人群需测骨密度

众所周知,糖尿病可导致多种的代谢异常。不仅有糖、蛋白质、脂肪代谢的紊乱, 还有钙代谢负平衡和骨代谢异常。糖尿病性骨质疏松症是糖尿病在骨骼系统出现的严重并发症。

Arthritis Rheumatol:银屑病的结构性肌腱附着点病变与出现银屑病关节炎的风险升高相关

在银屑病患者中,存在结构性附着点病变和附着点皮质vBMD低与出现PsA的风险升高相关。

Lancet Gastroen Hepatol:替诺福韦艾拉酚胺治疗HBV感染

与替诺福韦二吡呋酯相比,替诺福韦艾拉酚胺的疗效相当,且更为安全

Bone Research :骨密度和非骨表型之间多效性的全基因组相关性研究

骨质疏松症是全球最常见的代谢性骨病,可引起低创伤性骨折,从而导致较高的发病率和死亡率。特别是在高收入国家,骨质疏松性骨折导致老年人的健康寿命大大减少。

JCEM:甲状旁腺激素与骨密度的关系

这项研究表明血清PTH浓度与几处骨骼的BMD呈负相关。进一步的分析显示,血清PTH水平与BMD之间存在部位和年龄的相关性,这意味着血清高PTH水平促进骨质疏松症的发生发展。

Baidu
map
Baidu
map
Baidu
map