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Sci Rep:冬虫夏草的另一个重大作用!

2017-03-22 MedSci MedSci原创

佐剂是许多疫苗的常见组成部分,但是由于其疗效较低或是相关副作用,被许可使用人体的几乎没有。目前,一些研究通过采用系统药理学分析作为筛选中药佐剂的新策略。在中国和其他一些亚洲国家已经使用了多年“冬虫夏草”,但其药理学机制还没有完全阐明。近期,一项发表在杂志Sci Rep上的研究回顾了冬虫夏草中17种活性化合物中190种假定的物质,并采用系统药理学方法,为药物的药理作用提供新的见解。途径浓缩分析发现,

佐剂是许多疫苗的常见组成部分,但是由于其疗效较低或是相关副作用,被许可使用人体的几乎没有。目前,一些研究通过采用系统药理学分析作为筛选中药佐剂的新策略。在中国和其他一些亚洲国家已经使用了多年“冬虫夏草”,但其药理学机制还没有完全阐明。


近期,一项发表在杂志Sci Rep上的研究回顾了冬虫夏草中17种活性化合物中190种假定的物质,并采用系统药理学方法,为药物的药理作用提供新的见解。

途径浓缩分析发现,目标物质参与了若干免疫过程。基于此,研究者们选择虫草素作为目标化合物以研究其作为乙型肝炎疫苗的佐剂(因为现有的疫苗通常不能在受试者中诱导有效的免疫应答)。

最终,动物和细胞实验证实,新疫苗同时改善了BALB / c小鼠的体液免疫和细胞免疫并且没有副作用。

此项研究结果表明,虫草素可以作为乙型肝炎疫苗的佐剂,并且系统药理学分析可以用作选择佐剂的新方法。

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    2017-04-29 laoli

    谢谢分享!

    0

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    2017-03-25 6888

    hi咯now将近酒

    0

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    2017-03-23 6888

    好好个咯啦咯啦咯

    0

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    2017-03-23 中维2015

    虫草不是刚被踢出保健品么?

    0

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    2017-03-23 ylzr123

    虫草素可以作为乙型肝炎疫苗的佐剂,并且系统药理学分析可以用作选择佐剂的新方法。

    0

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    2017-03-22 爱的天使

    想不到冬虫夏草有这功效

    0

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    2017-03-22 yafeiliutjh

    博大精深文化

    0

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    2017-03-22 Albert Wu

    此项研究结果表明,虫草素可以作为乙型肝炎疫苗的佐剂,并且系统药理学分析可以用作选择佐剂的新方法

    0

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