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阿尔茨海默病(AD)诊断标准指南更新

2011-04-28 MedSci原创 MedSci原创

阿尔茨海默病指南
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　　阿尔茨海默病（AD）新诊断标准于2011年4月19日在线发表于《阿尔茨海默病与痴呆》（Alzheimers Dement）杂志。这是27年来AD诊断标准的首次更新。 　　新诊断标准分为3个部分：AD痴呆诊断标准、AD相关轻度认知障碍（MCI）诊断标准和临床前期AD诊断标准。AD诊断仍主要依靠患者临床表现。 　　新AD痴呆诊断标准具有极大的灵活性。无论是缺乏影像学和脑脊液检查等辅助

　　阿尔茨海默病（AD）新诊断标准于2011年4月19日在线发表于《阿尔茨海默病与痴呆》（Alzheimers Dement）杂志。这是27年来AD诊断标准的首次更新。 　　新诊断标准分为3个部分：AD痴呆诊断标准、AD相关轻度认知障碍（MCI）诊断标准和临床前期AD诊断标准。AD诊断仍主要依靠患者临床表现。 　　新AD痴呆诊断标准具有极大的灵活性。无论是缺乏影像学和脑脊液检查等辅助检查手段的全科医生，还是专业的临床研究人员都可以在实践中以此为依据。新MCI诊断标准基本与过去10年诊断标准相似，但从以下4个层面讨论了生物标志物对明确诊断的作用：① 患者认知功能改变；② 一项或多项认知功能下降证据；③ 患者在日常生活中基本保持功能的独立性；④ 患者无明显痴呆表现。 　　新诊断标准的另一特点是新纳入了仅以研究为目的的临床前期AD诊断标准。设立此项标准的目的为推进AD高风险人群的早期发现，以及在病理生理层面上诊断AD。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2012-03-04 lxg951

    #指南更新#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2012-01-20 ms1948154235210413

    #阿尔茨#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2011-09-06 12498da4m32(暂无昵称)

    #阿尔茨海#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2011-12-20 90isheng

    介绍的动态很及时，可否有链接供详细了解？

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2011-07-14 fuchengqiu

    很好，希望提供更详尽的资料。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2011-06-08 liuhg589

    较简单。

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2011-04-30 spoonycyy

    #诊断标准#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1988192, encodeId=3eac1988192a7, content=<a href='/topic/show?id=327e563967e' target=_blank style='color:#2F92EE;'>#指南更新#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56396, encryptionId=327e563967e, topicName=指南更新)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 04 17:50:00 CST 2012, time=2012-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1816493, encodeId=c968181649327, content=<a href='/topic/show?id=17b59e77626' target=_blank style='color:#2F92EE;'>#阿尔茨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97776, encryptionId=17b59e77626, topicName=阿尔茨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Bnia2EtH2IvyBtniaWHPQOYAicsN3IAL1ZuPV7qyALcdCiawRJdEiafMxWTxzERQW7eeKg8HfCKCRK2CJicy073C4RJg/132, createdBy=464b2500186, createdName=ms1948154235210413, createdTime=Fri Jan 20 16:50:00 CST 2012, time=2012-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1817516, encodeId=03cd181e5167f, content=<a href='/topic/show?id=4c9f9e777ac' target=_blank style='color:#2F92EE;'>#阿尔茨海#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97777, encryptionId=4c9f9e777ac, topicName=阿尔茨海)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Tue Sep 06 14:50:00 CST 2011, time=2011-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3834, encodeId=a14438341e, content=介绍的动态很及时，可否有链接供详细了解？, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/16/cc94593b19031715fb38ccf9a73750d4.jpg, createdBy=d0e252621, createdName=90isheng, createdTime=Tue Dec 20 11:09:00 CST 2011, time=2011-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2583, encodeId=6334258395, content=很好，希望提供更详尽的资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4a142067, createdName=fuchengqiu, createdTime=Thu Jul 14 09:42:00 CST 2011, time=2011-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2353, encodeId=624423539a, content=较简单。, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d04939808, createdName=liuhg589, createdTime=Wed Jun 08 18:15:00 CST 2011, time=2011-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1384956, encodeId=9d8e1384956f2, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1469870, encodeId=00ce14698e000, content=<a href='/topic/show?id=45a79e7788c' target=_blank style='color:#2F92EE;'>#阿尔茨海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97778, encryptionId=45a79e7788c, topicName=阿尔茨海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c5917090900, createdName=yhj-time, createdTime=Sat Apr 30 12:50:00 CST 2011, time=2011-04-30, status=1, ipAttribution=)]
    2011-04-30 yhj-time

    #阿尔茨海默#

    0

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