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Nano Converg:植物来源制备的金-共轭纳米粒子可有效促进癌细胞的凋亡

2018-05-01 MedSci MedSci原创

本研究中,研究人员成功使用夹竹桃夹竹桃茎提取物中的植物化学物质(通常称为Karabi)在非常温和的条件下室温绿色合成稳定的金-缀合的纳米颗粒。通过表面等离子体共振光谱,高分辨率透射电子显微镜,X射线衍射研究和动态光散射来表征绿色合成的金缀合的纳米颗粒。深入探究了合成和稳定金-共轭纳米粒子(AuNPs)的机制。AuNPs对MCF-7乳腺癌细胞系的抗癌活性研究表明,AuNPs可高度有效对抗癌细胞的选择

本研究中,研究人员成功使用夹竹桃夹竹桃茎提取物中的植物化学物质(通常称为Karabi)在非常温和的条件下室温绿色合成稳定的金-缀合的纳米颗粒。通过表面等离子体共振光谱,高分辨率透射电子显微镜,X射线衍射研究和动态光散射来表征绿色合成的金缀合的纳米颗粒。

深入探究了合成和稳定金-共轭纳米粒子(AuNPs)的机制。AuNPs对MCF-7乳腺癌细胞系的抗癌活性研究表明,AuNPs可高度有效对抗癌细胞的选择性凋亡。其抗氧化活性方面,研究人员探究了夹竹桃的茎皮提取物在室温下对2,2-二苯基吡嗪基肼基的作用。此外,研究人员还证实AuNPs作为催化剂的使用。

原始出处:

Abir Chandan Barai, Koushik Paul, et al., Green synthesis of Nerium oleander-conjugated gold nanoparticles and study of its in vitro anticancer activity on MCF-7 cell lines and catalytic activity. Nano Converg. 2018; 5(1): 10. doi:  10.1186/s40580-018-0142-5

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    2018-07-20 xuyong535
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    2018-05-03 yxch36
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    2018-05-01 semrour

    医学的进步就是抗癌.灭癌.防癌.真正到了实现的那一天.人类就幸福啦

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1745286, encodeId=292b1e45286e4, content=<a href='/topic/show?id=bdc262694bb' target=_blank style='color:#2F92EE;'>#植物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62694, encryptionId=bdc262694bb, topicName=植物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a5e35527958, createdName=xuyong535, createdTime=Fri Jul 20 18:10:00 CST 2018, time=2018-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1772956, encodeId=92f21e7295618, content=<a href='/topic/show?id=89f3e742947' target=_blank style='color:#2F92EE;'>#纳米粒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77429, encryptionId=89f3e742947, topicName=纳米粒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8ae38449394, createdName=zjubiostat, createdTime=Sun Jul 08 01:10:00 CST 2018, time=2018-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252501, encodeId=3b0812525013f, content=<a href='/topic/show?id=3efee1519b2' target=_blank style='color:#2F92EE;'>#癌细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71519, encryptionId=3efee1519b2, topicName=癌细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cea26, createdName=yxch36, createdTime=Thu May 03 04:10:00 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580633, encodeId=c1cb158063386, content=<a href='/topic/show?id=d4c6e7430be' target=_blank style='color:#2F92EE;'>#纳米粒子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77430, encryptionId=d4c6e7430be, topicName=纳米粒子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eedc16636878, createdName=ms920641618706883, createdTime=Thu May 03 04:10:00 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311017, encodeId=effe31101e6b, content=医学的进步就是抗癌.灭癌.防癌.真正到了实现的那一天.人类就幸福啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cabb1969833, createdName=semrour, createdTime=Tue May 01 18:55:05 CST 2018, time=2018-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310987, encodeId=db7531098eb7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue May 01 13:30:29 CST 2018, time=2018-05-01, status=1, ipAttribution=)]
    2018-05-01 惠映实验室

    学习了.谢谢分享.

    0

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