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盘点:抑郁重视了但也不可忽视与其同行的焦虑

2016-09-17 MedSci MedSci原创

这两日受乔任梁死亡的影响,抑郁症备受公众关注,但是与此同时切不可忽视焦虑。焦虑和抑郁从本质上是不同的,抑郁的基础是绝望和无助,而焦虑的原因往往是对不确定性的恐惧。事实上,近50%被诊断存在抑郁症的人同时存在焦虑症;反之亦然。这里小M整理了今年以来关于焦虑危害的重要研究进展与大家一同分享。【1】AF患者合并抑郁或焦虑,死亡率较高该研究旨在研究初级护理中抑郁和焦虑是房颤患者各种原因死亡的危险因素。

这两日受乔任梁死亡的影响,抑郁症备受公众关注,但是与此同时切不可忽视焦虑。焦虑和抑郁从本质上是不同的,抑郁的基础是绝望和无助,而焦虑的原因往往是对不确定性的恐惧。事实上,近50%被诊断存在抑郁症的人同时存在焦虑症;反之亦然。这里小M整理了今年以来关于焦虑危害的重要研究进展与大家一同分享。


这里可以进行抑郁小测试:点击进入测试

【1】AF患者合并抑郁或焦虑,死亡率较高

该研究旨在研究初级护理中抑郁和焦虑是房颤患者各种原因死亡的危险因素。

研究包括瑞典75所初级护理中心内被确诊为房颤的45岁及以上患者(n = 12 283)。应用Cox回归分析(HR值和95%CI)来探寻抑郁或焦虑和各种原因死亡之间的相关性。校正混杂因素后,对男性和女性都进行了分析。在二级分析中,探寻背景因素及其与焦虑或抑郁的关联。

结果:与非抑郁患者相比,完全校正后,患有抑郁的男性的各种原因死亡率的风险较高(HR = 1.28, 95% CI 1.08-1.53)。对于患有AF的男性焦虑患者及女性焦虑或抑郁患者,未发现与死亡存在明显关联。抑郁的AF患者中,心血管疾病更加常见。(文章详见——Ann Med:AF患者合并抑郁或焦虑,死亡率较高



【2】研究表明焦虑和皮肤病存在相关性

2016年,美国焦虑和抑郁学会年会称,焦虑症和皮肤病具有相关性。其研究发现有助于促进焦虑和身体健康问题的研究领域。结果强调了对皮肤病患者评估焦虑症状的重要性,并建议对患者进行辅助认知行为治疗可能让其受益。

研究人员对就诊皮肤科门诊的115名患者进行了研究,参与者平均年龄51.77岁,所有参与者完成了关于一般性焦虑、焦虑敏感性和社交焦虑症状的问卷调查。

调查结果显示,精神皮肤病学条件下的患者与非精神皮肤病学条件下的患者相比,焦虑敏感性更高,社交焦虑症状更严重。校正年龄、性别后,焦虑敏感社会问题是区分皮肤病类别的唯一重要因素。(文章详见——ADAA 2016:研究表明焦虑和皮肤病存在相关性

【3】术前抑郁焦虑,直肠癌术后患者预后不佳


该研究旨在于评估直肠癌患者术后2年的生活质量(QoL)、机体健康状况和个人幸福感。 研究人员选取了872名在2010年11月-2012年3月接受直肠癌手术的患者进行调查,并在他们手术后3、9、15、24个月候再次评估他们的生命质量、机体健康状况、幸福感、疾病处理能力(自我效能感)、社会支持、继发疾病、人口统计学特征、临床表现和治疗特点等等。 同时分组进行线性回归分析以评估患者生活质量、机体健康状况和个人幸福感的差异。

通过研究分析确定了4组的预后结果。第1组和第2组表现相似,得分均不低于平均分。70.5%的患者QoL得分提高,33.0%的患者机体健康状况得以明显好转,77.6%的患者幸福感较以往明显增加。第3组患者的表现稍差:24.2%的患者QoL得分增加,59.3%的患者机体健康状况改善,18.2%的患者自诉幸福感增加。第4组患者的表现最差,5.3%的患者QoL得分提高,7.4%的患者机体健康状况改善,4.2%的患者幸福感增加。直肠癌术前患者的焦虑情绪越强、自我效能越低,则术后患者的QoL得分、幸福感得分越低,预后也差。校正疾病特点、社会支持等因素后该关联依旧存在。(文章详见——PLOS one:术前抑郁焦虑,直肠癌术后患者预后不佳



【4】焦虑是心血管疾病的危险因素


焦虑是否是一系列心血管疾病的危险因素目前还不清楚。本研究旨在确定焦虑和一系列心血管疾病的相关性。结果发现,焦虑症与一系列不同的心血管事件的风险升高相关,包括卒中,冠心病,心脏衰竭,心血管死亡。但是这些关联是否是因果关系尚不清楚。

搜索MEDLINE和EMBASE中相关研究,最后确定了46个队列研究,包含2017276例受试者和222253例焦虑患者。焦虑与心血管死亡率风险增高显著相关(冠心病、卒中、心力衰竭)。焦虑与主要心血管事件或房颤不相关,虽然CI范围较广。恐怖性焦虑比其他焦虑症与冠状动脉心脏疾病的发生风险较高更相关,创伤后应激障碍与卒中风险增加相关。灵敏度分析结果是大致一致。(文章详见——Am J Cardiol:荟萃分析显示焦虑是心血管疾病的危险因素

【5】产前暴露双酚A会增加儿子焦虑和抑郁风险

根据最近的研究结果,产前暴露双酚A与10-12岁男孩的抑郁和焦虑症状有关。来自哥伦比亚大学的研究人员对241名居住在曼哈顿北部的女性进行了研究,从妊娠直到后代10-12岁。根据孕晚期尿液和儿童3岁和5岁时尿液检测双酚A含量。

发现对于男孩,产前暴露双酚A最高含量组与最低组相比,表现出更多的抑郁症状。产前暴露双酚A最高含量组男孩的平均CDRS得分为29.5。接近13.2%的最高浓度组男孩CDRS得分≥40分,而最低浓度组和中等浓度暴露组所占比例分别只有3%和2.6%。对于男孩,产前暴露双酚A与RCMAS总分数和社会关系量表有关,但是对于女孩,没有发现类似的关联。校正潜在混杂因素后,产前暴露双酚A与男孩CDRS、RCMAS分数之间的关系仍存在。

无论男女,产后暴露双酚A与CDRS、RCMAS分数之间不具有相关性。(文章详见——Environ Res:产前暴露双酚A会增加儿子焦虑和抑郁风险



最后一图读懂焦虑如何影响你的健康


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    2016-10-12 1e10c84am36(暂无匿称)

    好文章,受益

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    2016-09-27 童小孩

    学习了,很受益,谢谢分享,继续关注中!

    0

  3. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sun Sep 18 10:51:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129982, encodeId=c4ac1299826f, content=心理疾病越来越多,影响生活质量,临床必须关注。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Sun Sep 18 08:42:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129896, encodeId=6b921298967e, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-25 舒心和人

    良好的心情同样很重要,感谢分享

    0

  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sun Sep 18 10:51:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129982, encodeId=c4ac1299826f, content=心理疾病越来越多,影响生活质量,临床必须关注。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Sun Sep 18 08:42:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129896, encodeId=6b921298967e, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-19 李东泽

    很好,不错,以后会多学习

    0

  5. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-19 邓启付

    抑郁症是一个全社会必须重视和关心的问题,要及时发现身边的人并给予关心和治疗。

    0

  6. 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likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Sun Sep 18 10:54:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=130056, encodeId=fb7c130056b6, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Sun Sep 18 10:53:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=130055, encodeId=87de130055f2, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sun Sep 18 10:51:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129982, encodeId=c4ac1299826f, content=心理疾病越来越多,影响生活质量,临床必须关注。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Sun Sep 18 08:42:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129896, encodeId=6b921298967e, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-18 知难而进

    继续关注!

    0

  7. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-18 知难而进

    谢谢分享!

    0

  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-18 xiaotaiyang1

    了解一下

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sun Sep 18 10:51:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129982, encodeId=c4ac1299826f, content=心理疾病越来越多,影响生活质量,临床必须关注。, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Sun Sep 18 08:42:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129896, encodeId=6b921298967e, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Sun Sep 18 08:06:00 CST 2016, time=2016-09-18, status=1, ipAttribution=)]
    2016-09-18 言西早

    心理疾病越来越多,影响生活质量,临床必须关注。

    0

  10. 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    2016-09-18 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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