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Eur Respir J:胸膜感染患者合并症和结局

2019-08-09 xing.T MedSci原创

由此可见,胸膜感染患者合并症较多,住院时间较长。大多数报告的数据来自高收入地区。需要来自低收入地区的数据,以便更好地了解地区趋势,并实现最佳的资源供应。

胸膜感染仍然是死亡的重要原因。近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,该研究旨在调查胸膜感染患者先前存在的合并症和临床结局。

研究人员通过对Embase和Medline的检索,确定了2000年至2017年间报告有胸膜感染成人的研究。报告了结核、真菌或肺切除术后感染的研究被排除在外。两名评审员评估了20980篇文献。

211项研究符合纳入标准。134篇文献(227898名患者,平均年龄52.8岁)报告了合并症和/或结局数据。大多数研究是回顾性观察队列(n=104,78%),最常见的报告区域是东亚(n=33,24%),其次是北美(n=27,20%)。85篇文献(50756名患者)报告了合并症。任何合并症的中位百分比率为72%(IQR为58-83%),最常见的是呼吸道疾病(20%,16-32%)和心脏病(19%,15-27%)。125篇文献(192 298名患者)报告了结局数据。中位停留时间为19天(IQR为13-27),住院或30天死亡率中位数为4%(IQR为1-11%)。 在高收入(n=100,74%)的地区,患者年龄较大(平均56.5 vs. 42.5岁,p<0.0001),但既往合并症的患病率和住院时间长短或死亡无显著差异。

由此可见,胸膜感染患者合并症较多,住院时间较长。大多数报告的数据来自高收入地区。需要来自低收入地区的数据,以便更好地了解地区趋势,并实现最佳的资源供应。 

原始出处:

Tamsin N. Cargill.A systematic review of comorbidities and outcomes of adult patients with pleural infection.Eur Respir J.2019.https://erj.ersjournals.com/content/early/2019/07/24/13993003.00541-2019

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    2020-02-07 lifestar
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    2019-08-09 龙胆草

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