Baidu
map

Radiology:吸入超极化129Xe MRI在人脑灌注成像的价值。

2017-09-21 shaosai MedSci原创

氙是一种化学元素,它的元素符号是Xe,它的原子序数是54,是一种无色无味的稀有气体,放电时呈蓝色。在地球大气层中存在痕量的氙。除了个别化合物外,氙化合物都是无色的。已知的氙的稳定同位素有9种(参见氙的同位素)。它还有40种不稳定的放射性同位素。氙的放射性同位素是研究太阳系早期历史的重要工具。氙-135是核裂变的产物之一,并用作核反应堆的中子吸收剂。氙可以用于制造氙光灯和氙弧灯,也是一种全身麻醉剂。

氙是一种化学元素,它的元素符号是Xe,它的原子序数是54,是一种无色无味的稀有气体,放电时呈蓝色。在地球大气层中存在痕量的氙。除了个别化合物外,氙化合物都是无色的。已知的氙的稳定同位素有9种(参见氙的同位素)。它还有40种不稳定的放射性同位素。氙的放射性同位素是研究太阳系早期历史的重要工具。氙-135是核裂变的产物之一,并用作核反应堆的中子吸收剂。氙可以用于制造氙光灯和氙弧灯,也是一种全身麻醉剂。本研究旨在评价利用磁共振(MR)成像结合吸入超极化氙129(129Xe)在直接行人脑灌注成像的可能性,并将结果发表在Radiology上。

本研究共纳入了3名健康志愿者,并在体行 129XeMRI检查。联合高产旋转交换泵129Xe偏振器、常规射频脉冲线圈和优化的梯度回波MRI序列来获得有足够信号灵敏度来进行人脑超极化129Xe成像。传统T1加权质子(氢质子1 [ 1H])图像和动脉自旋标记灌注图像作为对照组。

结果为,129Xe摄入图像的信噪比为31 ± 9,与传统T1加权图像和ASL灌注图像相比能够获得灰质相似的结构效果。

本研究表明,超极化129XeMRI是一种无须注射进行脑组织灌注成像的方法。该方法对通过完整血脑屏障血管外脑组织摄入的129Xe气体进行成像。

原始出处:

Rao MR, Stewart NJ, Griffiths PD, et al,Imaging Human Brain Perfusion with Inhaled Hyperpolarized 129Xe MR Imaging. Radiology. 2017.DOI: 10.1148/radiol.2017162881

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1988441, encodeId=62a41988441e7, content=<a href='/topic/show?id=7d62668e678' target=_blank style='color:#2F92EE;'>#灌注成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66876, encryptionId=7d62668e678, topicName=灌注成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7460166, createdName=zhang92560, createdTime=Thu Jun 14 00:46:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1751373, encodeId=d40d1e51373a4, content=<a href='/topic/show?id=42988492ec0' target=_blank style='color:#2F92EE;'>#脑灌注#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84927, encryptionId=42988492ec0, topicName=脑灌注)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a4236283426, createdName=hywen7338, createdTime=Thu Dec 21 08:46:00 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246396, encodeId=447424639695, content=很好的文章.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Sep 21 21:29:38 CST 2017, time=2017-09-21, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1988441, encodeId=62a41988441e7, content=<a href='/topic/show?id=7d62668e678' target=_blank style='color:#2F92EE;'>#灌注成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66876, encryptionId=7d62668e678, topicName=灌注成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7460166, createdName=zhang92560, createdTime=Thu Jun 14 00:46:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1751373, encodeId=d40d1e51373a4, content=<a href='/topic/show?id=42988492ec0' target=_blank style='color:#2F92EE;'>#脑灌注#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84927, encryptionId=42988492ec0, topicName=脑灌注)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a4236283426, createdName=hywen7338, createdTime=Thu Dec 21 08:46:00 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246396, encodeId=447424639695, content=很好的文章.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Sep 21 21:29:38 CST 2017, time=2017-09-21, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1988441, encodeId=62a41988441e7, content=<a href='/topic/show?id=7d62668e678' target=_blank style='color:#2F92EE;'>#灌注成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66876, encryptionId=7d62668e678, topicName=灌注成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7460166, createdName=zhang92560, createdTime=Thu Jun 14 00:46:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1751373, encodeId=d40d1e51373a4, content=<a href='/topic/show?id=42988492ec0' target=_blank style='color:#2F92EE;'>#脑灌注#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84927, encryptionId=42988492ec0, topicName=脑灌注)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a4236283426, createdName=hywen7338, createdTime=Thu Dec 21 08:46:00 CST 2017, time=2017-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246396, encodeId=447424639695, content=很好的文章.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Sep 21 21:29:38 CST 2017, time=2017-09-21, status=1, ipAttribution=)]
    2017-09-21 清风拂面

    很好的文章.谢谢分享

    0

相关资讯

JAMA:氙气可减少昏迷患者的脑损伤

来自临床前模型的证据表明,氙气可以防止急性全缺氧缺血性脑损伤后发展为脑损伤,但迄今为止,这些假定的神经保护性质尚未在人类研究中报道。原始出处:Ruut Laitio,Marja Hynninen,Olli Arola,et al.Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-

Baidu
map
Baidu
map
Baidu
map