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J Thorac Dis:肺移植后的眼科并发症

2019-01-19 MedSci MedSci原创

美国俄亥俄州阿克伦市克利夫兰诊所Akron General内科的Dhal U及Cole眼科研究所的Raju S等人近日在J Thorac Dis杂志上发表了一篇重要综述文章,作者系统论述了肺移植后的眼科并发症。

美国俄亥俄州阿克伦市克利夫兰诊所Akron General内科的Dhal U及Cole眼科研究所的Raju S等人近日在J Thorac Dis杂志上发表了一篇重要综述文章,作者系统论述了肺移植后的眼科并发症。

肺移植人群中的眼科并发症是鲜为人知的。这包括一系列疾病,从巨细胞病毒(CMV)视网膜炎、疱疹性角膜炎、假性疟原虫感染到非感染性并发症如后囊下白内障(PSCs)、环孢菌素视网膜病变和移植后淋巴组织增生性疾病(PTLD)等。这些疾病可能是由于高水平的免疫抑制、高龄和药物特异性副作用等原因造成。糖尿病等潜在的并发症也可能在发病机制中发挥了重要作用。患者可能出现各种症状,如视力模糊、混浊物或眼睛疼痛等。

只有高度警觉性的患者才能及时就医诊断。作者提醒,随着越来越多的移植手术在全球范围内进行,肺病专家和移植医生必须认识到这些常常是微妙的症状。任何视觉症状都应进行眼科检查,以便控制这些并发症,因为其中一些会带来系统性扩散和重大发病率的风险。

文章深入回顾了与肺移植后常见眼科并发症相关的常见症状、治疗方法和最新进展。虽然本文侧重于肺移植的患者群体,但作者指出,其他一些类似免疫抑制疗法治疗的实体器官移植病例,也可以借鉴其中一些并发症。

原文出处:

Dhal, U., et al., "For your eyes only": ophthalmic complications following lung transplantation. J Thorac Dis, 2018. 10(11): p. 6285-6297.

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    2019-06-23 yyj062
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    2019-03-14 丁鹏鹏
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    2019-01-19 若轩

    很新颖的研究点

    0

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